Tangential Flow Filtration Market Analysis by Product (Systems, Membrane Filters, and Accessories); by Material {Polyether Sulfone (PS), Polyvinylidene Difluoride (PVDF), Regenerated Cellulose, and Others}; by Technique (Ultrafiltration, Microfiltration, and Others), and by Application (Bioprocess, Viral Vector, Vaccine Purification, and Others) – Global Supply & Demand Analysis & Opportunity Outlook 2023-2035
Buy Now Report ID: 4839 | Published Date: Apr 17, 2023
The global tangential flow filtration market size is estimated to reach ~USD 15 Billion by the end of 2035 by growing at a CAGR of ~16.20% over the forecast period, i.e., 2023 – 2035. In addition to this, in the year 2022, the market size of the tangential flow filtration market was ~USD 3 Billion. The growth of the market can be attributed to the advances in biological science as well as the booming biotechnology sector along with the accelerating bio revolution globally. As per researchers, biological applications alone are anticipated to have a direct positive economic impact of up to ~USD 4 trillion a year over the next ten to 20 years.
In addition to these, factors that are believed to fuel the market growth of tangential flow filtration include the rise in biological innovations as well as the rapid introduction of clinical trials of vaccines, besides the search for effective therapies along with genome sequencing, and a deep investigation of both the origins and the transmission patterns of the virus. For instance, responses to the novel coronavirus—SARS-CoV-2, worldwide, illustrated substantial advances in biological science in just the past few years post-COVID-19. The speedy genome sequencing of the virus in a few weeks is a witness to the new world of biology. All these research and developments in the field of protein chemistry, immunology, molecular biology, biochemistry, and microbiology are predicted to present the potential for market expansion over the projected period.
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Base Year |
2022 |
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Forecast Year |
2023-2035 |
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CAGR |
~16.20% |
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Base Year Market Size (2022) |
~ USD 3 Billion |
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Forecast Year Market Size (2035) |
~ USD 15 Billion |
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Regional Scope |
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Growth Drivers
Challenges
The global tangential flow filtration market is segmented and analyzed for demand and supply by technique into ultrafiltration, microfiltration, and other techniques. Out of these techniques of tangential flow filtration, the ultrafiltration segment is estimated to gain the largest market share of about ~38% in the year 2035. The growth of the segment can be attributed to the rising prevalence of infectious diseases globally, including coronavirus, influenza A virus, and others as well as the increasing investment in research and development (R&D) in the field of biomedicine. According to the World Health Organization, the annual epidemics of seasonal influenza are responsible for about 3 to 5 million cases of severe illness, and nearly 290 000 to 650 000 respiratory deaths.
The global tangential flow filtration market is also segmented and analyzed for demand and supply by application into bioprocess, viral vector, vaccine purification, and others. Amongst these segments, the viral vector segment is expected to garner a significant share of around ~46% in the year 2035. The expanding R&D in the field of molecular biology as well as the rising clinical trials of cell therapies are anticipated to boost the segment growth over the forecast period. On the other hand, the bioprocess segment is projected to witness a massive CAGR during the forecast period, owing to the rapidly rising demand for biological products with the growing biotechnology and biopharmaceutical industries. This, as a result, is anticipated to create numerous opportunities for the growth of the segment in the coming years.
Our in-depth analysis of the global tangential flow filtration market includes the following segments:
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By Product |
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By Material |
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By Technique |
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By Application |
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The market share of tangential flow filtration in North America, amongst the market in all the other regions, is projected to be the largest with a share of about ~35% by the end of 2035. The growth of the market can be attributed majorly to the increasing growing investment in R&D in the biopharmaceutical sector as well as growing advancements in the field of biotechnology along with rising employment of tangential flow filtration methods for the separation and purification of biomolecules in the area of biological fields. For instance, it was found that the biopharmaceutical industry in the U.S. invested around USD 102 billion into R&D in 2018.
The Asia Pacific tangential flow filtration. The market is estimated to be the second largest, registering a share of about ~30% by the end of 2035. The growth of the market can be attributed majorly to the growing existence of giant pharmaceutical manufacturers as well as increasing R&D in the field of biopharmaceuticals along with the rising inventions as well as innovations in the field of biologics and vaccines. The increase of CMOs in developing nations like China, Japan, and South Korea is another driving factor that leads to the market growth, as is the rising demand for biologics and pharmaceuticals, a sizable infusion of capital from domestic and foreign businesses, and these factors together. The desire for low-cost therapies, the modernization of medical procedures, and these factors will all contribute to the expansion of the TFF market in the region. Moreover, the uptrend installations of smaller bioreactors and multiproduct manufacturing facilities that have increased the demand for plug-and-play single-use TFF devices are also expected to boost the market growth in the region.
Further, the market in Europe, amongst the market in all the other regions, is projected to hold a majority of the share by the end of 2035. The increasing level of funding and investment by the government as well as the widening scope of biopharmaceuticals with the development of novel biological products are factors attributed to the growth of the market in the European region in the upcoming years.
Merck KGaA, the vibrant science and technology company, introduced three new products to support the flexible manufacturing of biologics, including first-of-its-kind single-use tangential flow filtration capsules for bioprocessing of antibody-drug conjugates and monoclonal antibodies.
Donaldson Company, a leading provider of innovative filtration products and solutions worldwide, acquired Solaris Biotechnology Srl. The lateral company designs and manufactures bioprocessing equipment, including bioreactors, fermenters, and tangential flow filtration systems for use in food and beverage, biotechnology, and other life sciences markets.
In 2023, market players might incur losses due to huge gap in currency translation followed by contracting revenues, shrinking profit margins & cost pressure on logistics and supply chain.
Controlling Inflation has become the first priority for global economies from last quarter of 2022 and to be followed in 2023. With skewed economic situations, rise in interest rate by governments to control spending and inflation, spiked oil and gas prices, high inflation, geo-political issues including U.S. & China trade war, Russia-Ukraine conflict to intensify the global economic issues.
The interest rates in the U.S. may be less sensitive in 2023 as compared to 2022; sigh of relief for businesses. Positive business sentiments, healthy business balance sheets, growth in construction spending (private construction value in 2022 stood at $1,429.2 billion, 11.7 percent (±1.0 percent) above the $1,279.5 billion spent in 2021, Residential construction in 2022 was $899.1 billion, up by 13.3 percent (±2.1 percent) from $793.7 billion in 2021, non-residential construction touched $530.1 billion, 9.1 percent (±1.0 percent) above the $485.8 billion in 2021.) showcases minimal impact of recession in the country.
Similarly, spiked spending in the European and major Asia economics including, India, China & Japan to showcase less impact on the global demand.
Author Credits: Radhika Gupta, Shivam Bhutani
Ans: The increasing spending in the field of protein chemistry, immunology, molecular biology, biochemistry, and microbiology are the major factors driving the market growth.
Ans: The market size of tangential flow filtration is anticipated to attain a CAGR of ~16.20% over the forecast period, i.e., 2023 – 2035.
Ans: The requirement of the huge cost of capital as well as changing market demand are estimated to be the growth hindering factors for the market expansion.
Ans: The market in the North American region is projected to hold the largest market share by the end of 2035 and provide more business opportunities in the future.
Ans: The major players in the market are Merck KGaA, Solaris Biotechnology Srl., Sartorius AG, Repligen Corporation, Sterlitech Corporation, and Parker Hannifin Corp.
Ans: The company profiles are selected based on the revenues generated from the product segment, the geographical presence of the company which determines the revenue generating capacity as well as the new products being launched into the market by the company.
Ans: The market is segmented by product, material, technique, application, and by region.
Ans: The ultrafiltration segment is anticipated to garner the largest market size by the end of 2035 and display significant growth opportunities.
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