Dental Membrane and Bone Graft Substitutes Market Size & Share, by Type (Dental Membrane, Bone Graft Substitutes); Material {Allograft (Demineralized Bone Matrix), Xenograft, Synthetic, Autograft}; Product Type (Bio OSS, OsteoGraf, Grafton); Application (Ridge Augmentation, Sinus Lift, Periodontal Defect Regeneration, Implant Bone Regeneration); End-user (Hospitals, Dental Clinics) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2023-2033

  • Report ID: 4273
  • Published Date: Mar 06, 2023
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2023-2035

Dental Membrane and Bone Graft Substitute Market size is anticipated to surpass USD 1,565 Million by the end of 2033, witnessing around 9% CAGR during the forecast period, i.e., 2023-2033. In the year 2022, the industry size of dental membrane and bone graft substitute was USD 645 Million. The primary growth factor of the dental membrane and bone graft substitutes market is increasing demand from DHO (dental homeopaths) and orthodontists owing to their use in treating certain oral health issues such as GERD, gum disease, TMJ problems, and tooth extraction/reconstruction surgeries. Additionally, the increasing number of dental implant surgeries around the world is also boosting this market. Dental implants are becoming increasingly popular as they offer greater stability and aesthetics for patients compared to traditional crowns or dentures. For instance, in the United States, there were more than 2.9 million dental implant procedures performed in 2019 before the COVID-19 outbreak.

Dental membranes and bone graft substitutes facilitate dental bone replacement treatments in patients suffering from dental diseases such as cavities, gum diseases, and oral cancer. Bone grafting for dental implants is performed by placing a dental membrane over the bone and underneath the gums. It prevents the gum from expanding into bones during healing by acting as a barrier. Moreover, the rising prevalence of oral disorders such as periodontal diseases, tooth loss, and decay among the population is expected to augment the growth of the global dental membrane and bone graft substitutes market during the forecast period. As per the statistics by the Centers for Disease Control and Prevention, the prevalence of the periodontal disease among adults aged 30 and older is 47.2% globally. The occurrence of this disease increases with age, with 70.1% of those 65 and older suffering from periodontal disease. Furthermore, increasing awareness of oral health, escalating oral disease, increased research and development (R&D) operations along with increased use of resorbable dental membranes and bone graft biomaterials are other factors expected to fuel the global dental membrane and bone graft substitutes market over the forecast period.

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Dental Membrane and Bone Graft Substitute Sector: Growth Drivers and Challenges

Growth Drivers

  • Increasing Elderly Population Around the World - As of the end of 2021, there were 747,238,580 people over 60 around the world, according to the World Bank. The number is expected to increase in the coming years. Oral health problems are more prevalent in older adults. A greater number of older people suffer from dental diseases, such as edentulism. Thus, the growing adoption of dental implants among the escalating elderly population is expected to enlarge the global dental membrane and bone graft substitutes market size during the forecast period.

  • Increasing Spending on Dental Services Worldwide - According to the Centers for Medicare & Medicaid Services, dental services accounted for a 3% share of overall healthcare spending in the United States. Also, the spending on dental services amounted to USD 142.4 billion in the year 2020. 

  • Growing Consumption of E-Cigarettes and Vaporizer Among Millennials - According to the Centers for Disease Control and Prevention, in 2021, about 2.8% of middle school students and 11.3% of high school students reported that they had used electronic cigarettes and vaporizers around the globe.

  • Rising Per Capita Income Worldwide – Throughout the world, per capita income in 2021 has increased by a total of 4.8% as compared to the global annual per capita income in 2020, which was down by -4.3%. 

  • Growing Trend of Dental Tourism - such as in China and India, owing to the availability of cost-effective dental implants which is expected to fuel dental membrane and bone graft substitutes market growth in the region. For instance, the cost of a dental implant in the United States is approximately USD 4,000 to USD 5,000. A similar dental implant in India costs around USD 550 on average.


  • Higher Cost Associated with Bone Graft Surgeries - Autografts are only used for very minor bone abnormalities owing to their higher surgical expenses and greater surgical risks, such as excessive bleeding, infection, inflammation, and discomfort. According to current data, 2.2 million bone transplant surgeries are projected to be conducted yearly globally, costing an estimated USD 664 million by 2021, with the number of surgical procedures for treating bone abnormalities predicted to increase by almost 13% annually.
  • Complications Involved in Bone Grafting Procedures
  • Lack of Dental Professionals and Specialists

Dental Membrane and Bone Graft Substitute Market: Key Insights

Base Year


Forecast Year




Base Year Market Size (2022)

~ USD 645 Million

Forecast Year Market Size (2033)

~ USD 1,565 Million

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)
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Dental Membrane and Bone Graft Substitute Segmentation

Type (Dental Membrane, Bone Graft Substitutes)

The global dental membrane and bone graft substitutes market is segmented and analyzed for demand and supply by type into the dental membrane and bone graft substitutes. Among these, the dental membrane segment captured the largest market size in the global dental membrane and bone graft substitutes market, owing to the increased number of dental graft surgeries performed each year in dental clinics. For instance, in 2019, the professionals collectively operated in more than 1250 dental clinics and placed over 320,000 dental implants a year globally. Moreover, the number of surgical procedures to restore bone defects is expected to increase by approximately 12% per year. Furthermore, the convenience of clinics, safer, faster same-day procedures, as well as the easy availability of surgeons along with increasing awareness of oral health are expected to augment segment growth during the forecast period.

End-user (Hospitals, Dental Clinics)

The global dental membrane and bone graft substitutes market is also segmented and analyzed for demand and supply by end user into hospitals and dental clinics. Out of these the dental clinics segment is expected to achieve the largest market share by 2033. This can be owed to the fact that dentists are usually well equipped to perform various dental treatments and operations in their clinics. For instance, there were over 200,000 dentists in the U.S. in 2020.

Our in-depth analysis of the global market includes the following segments:

          By Type

  • Dental Membrane
  • Bone Graft Substitutes

           By Material

  • Allograft
  • Xenograft
  • Synthetic
  • Autograft

           By Product Type

  • Bio OSS
  • OsteoGraf
  • Grafton

          By Application

  • Ridge Augmentation
  • Sinus Lift
  • Periodontal Defect Regeneration
  • Implant Bone Regeneration
  • Others

             By End-User

  • Hospitals
  • Dental Clinics

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Dental Membrane and Bone Graft Substitute Industry - Regional Synopsis

North American Market Forecast   

The North America dental membrane and bone graft substitutes market, amongst the market in all the other regions, is projected to hold the largest market share by the end of 2033, owing to the surge in the cases of dental problems and injuries along with the increasing number of people visiting the dentist in the region. For instance, more than 65% of the population aged between 18 and 64 went for dental visits in 2019 in North America. Moreover, the availability of surgeons, an increase in the number of geriatric patients suffering from dental problems, and the increasing use of bone graft substitutes are projected to drive market growth in the region during the forecast period.

Europe Market Forecast

The market in Europe is estimated to witness noteworthy growth over the forecast period owing to a developed healthcare system and rising government spending on dental treatment, in the region. For instance, there were about 6 million tooth implants in Europe in 2020. The market's expansion is also attributable to the presence of numerous pharmaceutical and biotechnology companies, an increase in the volume of surgeries, and growing public knowledge about periodontology.

Research Nester
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Companies Dominating the Dental Membrane and Bone Graft Substitute Landscape

    • Dentsply Sirona
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Straumann AG
    • Zimmer Biomet Inc.
    • Biohorizons Inc
    • Geistlich Pharma Ag
    • Rti Surgicals
    • Dentium Co, Ltd.
    • Lifenet Health
    • Medtronic plc
    • Orthogen AG


In The News

  • Straumann AG - PlusDental, a doctor-led-clear-aligner and provider of orthodontic treatment solutions has been acquired by Straumann Group.

  • Medtronic plc - launched the Grafton (TM) Demineralized Bone Matrix (DBM) bone grafting product for spine and orthopedic procedures, which is the first and only demineralized bone matrix product available in Japan.

Author Credits:  Radhika Gupta, Shivam Bhutani

  • Report ID: 4273
  • Published Date: Mar 06, 2023
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

Rising prevalence of oral diseases, increasing geriatric population along with increasing awareness about oral health are the major factors driving the growth of the dental membrane and bone graft substitutes market.

The market is anticipated to attain a CAGR of 9% over the forecast period, i.e., 2023-2033.

Higher cost associated with bone graft surgeries along with lack of dental professionals and specialists are the challenges affecting the market growth.

The market in North America holds the largest market share in 2033 and provides more business opportunities in the future

The major players in the market are Dentsply Sirona, Straumann AG, Zimmer Biomet, Biohorizons Inc, Geistlich Pharma Ag, Rti Surgicals, Dentium Co, Ltd., Lifenet Health, Medtronic plc, Orthogen, and others.

The company profiles are selected based on the revenues generated from the product segment, the geographical presence of the company which determines the revenue generating capacity as well as the new products being launched into the market by the company.

The market is segmented by type, material, product type, application, end-user, and by region.

The dental membrane segment captures the largest market size in 2033 and displays significant growth opportunities.
Dental Membrane and Bone Graft Substitutes Market Report Scope

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