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Tooth Regeneration Market Size and Forecast, by Application (Enamel, Dentin, Pulp); Demographic (Geriatric, Adults, Middle-aged); Type (Hard, Soft Tissue) - Growth Trends, Key Players, Regional Analysis 2026-2035

  • Report ID: 6197
  • Published Date: Sep 17, 2025
  • Report Format: PDF, PPT

Tooth Regeneration Market Outlook:

Tooth Regeneration Market size was over USD 5.03 billion in 2025 and is anticipated to cross USD 9.09 billion by 2035, witnessing more than 6.1% CAGR during the forecast period i.e., between 2026-2035. In the year 2026, the industry size of tooth regeneration is assessed at USD 5.31 billion.

Tooth Regeneration Market Size
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The growing number of dental health issues affect people throughout their lifetime causing pain, discomfort, disfigurement, and even death in extreme cases is driving the market growth of the tooth regeneration market. According to a WHO report issued in 2023, oral diseases affect nearly 3.5 billion people across the world in 2022 and around 2 billion people suffer from permanent teeth caries. The rate at which this disease is growing is due to urbanization and lifestyle changes, majorly due to inadequate exposure to fluoride present in the water supply and oral hygiene products such as toothpaste, food with high sugar content, and poor access to oral health care.

Key Tooth Regeneration Market Insights Summary:

  • Regional Highlights:

    • North America tooth regeneration market will hold more than 34% share by 2035, driven by higher adoption rates of tooth regeneration due to dental health concerns.
    • Asia Pacific market will secure the second largest share by 2035, driven by the high prevalence of oral cancer and increasing demand for cosmetic dentistry.

  • Segment Insights:

    • The hard tissue segment in the tooth regeneration market is projected to hold a 62% share by 2035, fueled by rising cases of enamel hypoplasia, dental caries, and periodontitis.
    • The geriatric segment in the tooth regeneration market is projected to capture a 42% share by 2035, driven by tooth loss among the elderly impacting systemic health.

  • Key Growth Trends:

    • Growing cases of permanent tooth loss 
    • Increasing demand for dental regenerative therapies

  • Major Challenges:

    • Expensive cost of tooth regenerative therapies 
    • Unavailability of skilled people and infrastructure 

  • Key Players: Zimmer Biomet, Dentsply Sirona, Institut Straumann AG, CAMLOG Biotechnologies GmbH, BioHorizons, Keystone Dental Group, Clove Dental, STEMCELL Technologies, Integra LifeSciences, Cyro life.

Global Tooth Regeneration Market Forecast and Regional Outlook:

  • Market Size & Growth Projections:

    • 2025 Market Size: USD 5.03 billion
    • 2026 Market Size: USD 5.31 billion
    • Projected Market Size: USD 9.09 billion by 2035
    • Growth Forecasts: 6.1% CAGR (2026-2035)

  • Key Regional Dynamics:

    • Largest Region: North America (34% Share by 2035)
    • Fastest Growing Region: Asia Pacific
    • Dominating Countries: United States, Japan, Germany, China, United Kingdom
    • Emerging Countries: China, Japan, South Korea, India, Brazil

    • Last updated on : 17 September, 2025

Growth Drivers

  • Growing cases of permanent tooth loss - Dental caries and periodontal disease are the most common reasons for tooth loss among the population. It majorly happens due to improper cleaning of teeth and gums which leads to them harboring bacteria which can destabilize teeth. After losing a tooth and not replacing it with an artificial one, the supporting bone will start to degrade slowly and melt away.

    The remaining teeth then start to shift to fill the space. To prevent such situations, tooth regeneration therapies are introduced to the people. As per the WHO report issued in 2023, periodontal diseases are anticipated to affect around 19% of the global adult population, representing more than 1 billion cases worldwide. The global average frequency of complete tooth loss is almost 7% among people aged 20 years or older.
  • Increasing demand for dental regenerative therapies -Regenerative therapy is an innovative approach for dental procedures. These procedures use advanced technologies such as digital dental impression and materials to utilize the human body’s natural healing potential, due to which dentists prefer these treatments for patients to recover rapidly.  This therapy helps with restoring damaged tissue such as bone and gums to promote better oral health as it addresses the root cause and aims to stimulate true healing.  

    These therapies include guided tissue regeneration, bone grafting, and platelet-rich plasma. As per the latest report published in 2023, around 2.2 million bone graft procedures, costing an estimated USD 664 million were performed in 2021 worldwide. The number of operative procedures for repairing bony defects is foreseen to grow by 13% annually.

Challenges

  • Expensive cost of tooth regenerative therapies - Tooth regenerative therapies are highly unaffordable to people which can hinder the growth of the tooth regeneration market. The high cost of materials that are required during the therapy is the primary factor that is making these therapies uneconomical due to which common people are unable to access these treatments.
  • Unavailability of skilled people and infrastructure - A significant obstacle in the market expansion for tooth regeneration is the lack of infrastructure and experience required to perform regenerative therapies. Specialized knowledge and skills are required for these therapies, which are generally not accessible to everyone. Additionally, the infrastructure is not easily accessible to people, making it difficult for them to opt for these treatments.

Tooth Regeneration Market Size and Forecast:

Report Attribute Details

Base Year

2025

Forecast Period

2026-2035

CAGR

6.1%

Base Year Market Size (2025)

USD 5.03 billion

Forecast Year Market Size (2035)

USD 9.09 billion

Regional Scope

  • North America (U.S. and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC, North Africa, South Africa, Rest of the Middle East and Africa)
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Tooth Regeneration Market Segmentation:

Type Segment Analysis

Hard tissue segment is projected to dominate around 62% tooth regeneration market share by the end of 2035. The segment growth can be attributed to the growing cases of enamel hypoplasia, dental caries, and periodontitis.

Moreover, several studies have been conducted which say that hard dental tissues are used to determine the Rh factor and ABO blood grouping in humans. According to the World Health Organization report issued in 2023, periodontal diseases are evaluated to affect around 19% of the global adult population, which means more than 1 billion cases worldwide. 

Application Segment Analysis

By 2035, enamel segment is expected to account for around 37% tooth regeneration market share. The growth of the segment can be impelled by the advancements in the regenerative medicine sector and dental equipment. Enamel provides the overall shape of the tooth and the enamel cells are arranged in programmed temporal and spatial sequence.

Additionally, enamel is not made up of living cells which means it does not grow back and repair naturally in case of any damage. According to the latest report issued in 2020 states, enamel is a mixture of inorganic particles. It consists of 95% to 98% calcium, phosphates, and ions that add up to make hydroxyapatite crystals.

Demographic Segment Analysis

In tooth regeneration market, geriatric segment is expected to dominate over 42% revenue share by 2035. This growth is taking place due to tooth loss taking place in the old population, which reduces nutrient supplementation. These factors contribute to systemic health issues.

 Additionally, cases of periodontal disease have symptoms including bleeding gums, wobbly teeth, and deterioration of the jawbone are responsible for tooth loss in the elderly population. According to a WHO report published in 2023, the predicted global average frequency of complete tooth loss is almost 7% among people aged 20 years or older. For people aged 60 years or older, the expected frequency of tooth loss is 23%.

Our in-depth analysis of the tooth regeneration market includes the following segments:

          Type
  • Hard Tissue
  • Soft Tissue

          Application
  • Enamel
  • Dentin
  • Pulp

          Demographic
  • Geriatric
  • Adults
  • Middle-Aged
Vishnu Nair
Vishnu Nair
Head - Global Business Development

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Tooth Regeneration Market Regional Analysis:

North American Market Insights

North America industry is estimated to account for largest revenue share of 34% by 2035. The market growth in the region is due to a higher adoption rate of tooth regeneration. According to the National Center for Health Statistics report issued in 2024, 46% of children from 2 to 19 years are suffering from untreated or restored dental caries in one or more permanent teeth (2017-March 2020) due to which people started opting for tooth regeneration procedures driving the tooth regeneration market growth.

The geriatric population in the US is growing, and the ratio of tooth loss is quite high in elderly people. As per the National Center for Health Statistics report issued in 2024, around 13.2% of suffered from complete tooth loss from 65 years and older.

The prevalence of edentulism is high enough in Canada which majorly affects people above 20 years. According to a WHO report issued in 2022, around 7.7% population in the region suffered from edentulism in 2019 and the total expenditure on dental healthcare was USD 12,829 million.

APAC Market Insights

The APAC region will also encounter huge growth for the tooth regeneration market during the forecast period and will hold the second position owing to growing cases of oral cancer. According to the WHO report, the Southeast Asia region has the highest number of oral cancer cases and mortality rates among all WHO regions, with the poised age-standardized mortality for males (8.1 per 100 000). Additionally, more than 900 million cases of untreated dental caries, severe periodontal diseases, and edentulism are reported in the region.

The growing demand for cosmetic dentistry in China is driving the growth of the tooth regeneration market. People are opting for these treatments to enhance the physical appearance of their teeth.

The tooth regeneration market is expanding in Japan due to the technological advancements in healthcare infrastructure. The major key players are investing massively in healthcare infrastructure to improve access to healthcare services for the people. Treloar and Heisel, LLC launched “Pedia Roid” that is a pediatric simulation robot in 2023. This robotic dentistry technique was released to teach students how to handle an emotional patient for the first time.

Tooth Regeneration Market Share
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Tooth Regeneration Market Players:

    The major key players present in the tooth regeneration market focus on the production of premium quality dental equipment and discover dental innovations, products, and services.  

    • Zimmer Biomet
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Dentsply Sirona
    • Institut Straumann AG
    • CAMLOG Biotechnologies GmbH
    • BioHorizons
    • Keystone Dental Group
    • Clove Dental
    • STEMCELL Technologies
    • Integra LifeSciences
    • Cyro life

Recent Developments

  • Dentsply Sirona, and A-dec have announced that they have made an extension of their collaboration and the integration of the Dentsply Sirona Primescan Connect intraoral scanner with the A-dec 500 and A-dec 300 delivery systems. This will bring high efficiency to doctors’ workflow and significant value to their A-dec delivery systems.
     
  • Keystone Dental Group announced the commercial launch of the GENESIS ACTIVE Implant System. This state-of-the-art surgical solution will transform how dental professionals approach implant placement and restoration.
  • Report ID: 6197
  • Published Date: Sep 17, 2025
  • Report Format: PDF, PPT
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Frequently Asked Questions (FAQ)

In the year 2026, the industry size of tooth regeneration is assessed at USD 5.31 billion.

The global tooth regeneration market size surpassed USD 5.03 billion in 2025 and is projected to witness a CAGR of around 6.1%, crossing USD 9.09 billion revenue by 2035.

North America tooth regeneration market will hold more than 34% share by 2035, driven by higher adoption rates of tooth regeneration due to dental health concerns.

Key players in the market include Zimmer Biomet, Dentsply Sirona, Institut Straumann AG, CAMLOG Biotechnologies GmbH, BioHorizons, Keystone Dental Group, Clove Dental, STEMCELL Technologies, Integra LifeSciences, Cyro life.

Tooth Regeneration Market Report Scope

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