Sarcoma Drugs Market Size & Share, by Distribution Channel (Hospital Pharmacies, Retail & Specialty Pharmacies, Online Pharmacies); End user; Type; Treatment; Drug Class; Disease Indication - Global Supply & Demand Analysis, Growth Forecasts, Statistical Report 2026-2035

  • Report ID: 8010
  • Published Date: Aug 20, 2025
  • Report Format: PDF, PPT

Sarcoma Drugs Market Outlook:

Sarcoma Drugs Market size was USD 2.1 billion in 2025 and is predicted to reach USD 4.6 billion by the end of 2035, increasing at a CAGR of 9.2% during the forecast period, i.e., 2026-2035. In 2026, the industry size of sarcoma drugs is evaluated at USD 2.3 billion.

The market’s growth is highly driven by an increase in sarcoma cases, optimized diagnostic solutions, breakthroughs in targeted therapies, and the provision of private and government funding. According to a report published by NLM in April 2025, soft tissue sarcoma (STS), which is a kind of malignant tumor, accounts for only 1% of adult malignancies. In addition, the STS proportion is estimated to be 7% to 8% for pediatric cancer, thereby demanding age-based analysis. Besides, 50% to 60% of STS occurrences are identified in the extremities, thus enhancing the market’s demand. Meanwhile, the overall STS survival rate usually ranges between 60% to 80%, thus suitable for the market’s upliftment.

Monthly Cost of FDA-Approved Drugs (in USD)


                                                                                      

                                                                                                                                                     Source: NCBI
Moreover, immunotherapy has gradually emerged as one of the essential pillars in combating sarcoma, thereby denoting another factor for the market upliftment. As per the October 2022 NLM report, cancer has resulted in 10 million deaths, of which 2 million cases account for breast cancer. Besides, to successfully conduct immunotherapy, the US Food and Drug Administration (FDA) has approved 42% of cancer drugs, which is readily driving the market’s growth. Meanwhile, as stated in the April 2024 NLM article, the 30-day dosing price range of sarcoma medications is between USD 11,162.8 to USD 46,926.0, thereby boosting the overall market globally.

Tabulation of Patient Burden, Drug Approvals, Average Wholesale Price (AWP), Median Progression-free Survival (PFS), & Cost of Therapy, (2013-2023)

Indication

Medication

Year of FDA Approval

Incidence of Disease per 1,000,000 People

AWP in USD

Time for AWP (Days)

Price for 30 Days of Drug (1 Month) in USD

Price for 12 Months of Drug in USD

Third line
treatment Gastrointestinal Stromal Tumor

Regorafenib

2013

10-15

21,628.32

28

23,173.20

444,925.32

Liposarcoma and Leiomyosarcoma

Trabectedin

2015

Liposarcoma: 7
Leiomyosarcoma: 5
 

9860.57

21

14,086.53

78,884.52

Liposarcoma who have received prior anthracycline

Eribulin

2016

Liposarcoma: 7

7814.00

21

11,162.86

93,768.24

Soft Tissue Sarcoma
nthracycline-containing is appropriate

Olaratumab

2016

47

11,788.80

21

16,841.14

169,758,72

Tenosynovial Giant Cell Tumor

Pexidartinib

2019

43

21,865.2

30

21,865.20

503,774.16

Gastrointestinal Stromal Tumor with PDGFRA Exon 18 Mutation

Avapritinib

2020

1.6

44,533.20

30

44,533.20

534,398.40

Epithelioid Sarcoma

Tazemetostat

2020

0.5

22,620.00

30

22,620.00

255,542.40

NF1 and Symptomatic Inoperable Plexiform Neurofibromas

Selumetinib

2020

NF1/NF2: 737

24,361.61

30

24,361.61

331,312.32

Kaposi Sarcoma

Pomalidomide

2020

6

43,280.00

28

46,371.43

556,465.56

Gastrointestinal Stromal Tumor

Ripretinib

2020

10-15

46,926.00

30

46,926.00

563,112.00

Perivascular Epithelioid Cell Tumor

Sirolimus Protein-Bound Particles

2021

0.3

28,940.80

21

41,344.00

347,292.00

Inflammatory Myofibroblastic Tumor

Crizotinib

2022

Less than 1

25,389.00

30

25,389.00

304,674.72

Alveolar Soft Part Sarcoma

Atezolizumab

2022

Less than 1

12,416.00

21

17,737.14

149,000.16

Desmoid Tumors

Nirogacestat

2023

3 to 5

34,800.00

28

37,285.71

447,428.52

 

Sarcoma Drugs Market Size
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Growth Drivers

  • Artificial intelligence-powered drug repurposing: The market is experiencing transformation, owing to AI and digital health convergence. According to an article published by NLM in July 2025, the binary classification of implementing AI, machine learning, and specialized radiomics resulted in a 76.02% accuracy rate. In addition, the FNCLCC grade classification reached 57.6% accuracy, thereby making it valuable for combining innovative technologies to demonstrate wavelength transformation to enhance sarcoma drugs performance.
  • Liquid biopsy integration: This is a minimally invasive and innovative diagnostic tool to ensure cancer management, which is positively impacting the sarcoma drugs market globally. This tool provides a repeatable and accessible procedure for effectively tracking the cancer progress. As per the February 2023 NLM article, the overall liquid biopsy market is projected to surge to approximately 16% by the end of 2030, thereby making it suitable to aid cancer. Besides, with its implementation, an estimated 70% of patients with Stage I cancer can undergo standard treatment to provide a cure and reduce side effects, in comparison to radiotherapy and chemotherapy.
  • Orphan drug incentives: The sarcoma drugs market’s upliftment readily depends on orphan drug to gain exclusivity, tax credits, and EMA fee waivers. Besides, organizations investing in launching latest sarcoma drugs are required to receive this integration through administrative approval. For instance, in September 2022, Avacta Group plc announced that the U.S. FDA has successfully granted the Orphan Drug Designation (ODD) for the company’s leading pre-CISION drug candidate, AVA6000, which is suitable for aiding soft tissue sarcoma.

Patient Pool Affected with STS Driving the Market

Country and Region-Wise STS Incidences

Countries/Regions

Incidences

U.S.

13,400 individuals

China

2.9 per 100,000

Europe

4 to 5 per 100,000

UK

3,300 people

China

1.8 per 100,000

Italy

1.7 per 100,000

Netherlands

4.7 per 100,000

Serbia

1.9 per 100,000

Sources: NLM, April 2025; NLM, November 2024; MDPI, January 2022

Historical Pricing Strategy and Its Impact on the Sarcoma Drugs Market Expansion

Lenalidomide (Revlimid) Pricing & Profit Strategy Analysis (2005-2020)

Year

Price per Pill (USD)

Price Increase (%)

1-Month Supply Cost (USD)

Key Events

Revenue Impact (USD Billion)

Executive Compensation Ties

2005

215

-

4,515

FDA approval (multiple myeloma)

-

-

2019

763

+6 (BMS acquisition)

16,023 (held)

Celgene acquired by Bristol Myers Squibb (BMS)

9.7 yearly revenue (63% from the U.S.)

USD 400 million total exec compensation (2006 to 2017)

2020

-

-

16,023

Generic delays via patent thickets

53 yearly revenue (2009 to 2018)

Bonuses triggered by price hikes

Source: American Society of Clinical Oncology, February 2024

Challenges

  • Delay in administrative approvals: These represent a huge barrier in the market development since approval duration varies dramatically from region to region. These delays originated from numerous factors, including differences in evidentiary standards, demand for additional region-based data, and resource-driven constraints at regulatory agencies. Besides, the human cost is substantial and sarcoma patients frequently lack accessibility to any targeted therapies. Meanwhile, manufacturers are adopting strategies to escalate approvals by participating in review programs, thereby avoiding any further delays.
  • Payers’ demand for real-world data: The presence of health technology assessment bodies are continuously demanding actual evidence before catering to notable therapies, which has created a challenge in the market growth internationally. Despite conducting Phase III clinical trials, payers currently require longitudinal results from real clinical practice. The evidence needs are strict for precision medicines, which is causing a hindrance in the market’s expansion. However, manufacturers are positively responding to this issue by developing suitable RWE teams and collaborating with academic facilities.

Sarcoma Drugs Market Size and Forecast:

Report Attribute Details

Base Year

2025

Forecast Year

2026-2035

CAGR

9.2%

Base Year Market Size (2025)

USD 2.1 billion

Forecast Year Market Size (2035)

USD 4.6 billion

Regional Scope

  • North America (U.S., and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

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Sarcoma Drugs Market Segmentation:

Distribution Channel Segment Analysis

Based on the distribution channel, the hospital pharmacies segment in the sarcoma drugs market is projected to account for the largest share of 58.7% by the end of 2035. The segment’s growth is driven by cold-chain logistics and specialized administration to make sarcoma drugs readily available at a cost-effective price to patients. In this regard, a clinical study was conducted on 404,443 patients from the U.S., which was published by the New England Journal of Medicine in January 2024. This study comprised 4,727,189 drug-infusion visits, and the median price markup after the 340B discount was 3.0. Besides, this markup increased by 6.5 times after geographic, patient, and drug adjustments, thereby uplifting the overall segment.

End user Segment Analysis

Based on the end user, the specialty cancer centers segment in the sarcoma drugs market is expected to hold the second-largest share of 51.5% during the forecast timeline. The segment’s upliftment is propelled by its potential to serve as essential facilities for progressive sarcoma clinical and treatment research. These centers have readily excelled in providing precision-based therapies, such as CAR-T cell and NTRK inhibitor treatments, which demand customized facilities and multidisciplinary care teams. Besides, sarcoma patients in the U.S. have successfully received suitable treatment at NCCN-specific centers, owing to their expert knowledge in rare cancers, thus suitable for the segment’s growth.

Type Segment Analysis

Based on the type, the soft tissue sarcoma segment in the sarcoma drugs market is predicted to garner the third-largest share of 49.2% by the end of the forecast period. The segment’s development is fueled by an increase in therapeutic advancements and the incidence rate. As stated in the June 2023 NLM article, this particular sarcoma comprises Stage I, Stage II, Stage III, and Stage IV, wherein the tumor size is 5 centimeters in Stage 1A and Stage II, and more than 5 centimeters in Stage IB. Further, it is less than 10 centimeters in Stage IIIA and over 10 centimeters in Stage IIIB. For Stage IV, the size can be of any type and can easily spread near lymph nodes, thus denoting a huge demand for the market globally.

Our in-depth analysis of the market includes the following segments:

Segment

Subsegments

Distribution Channel

  • Hospital Pharmacies
  • Tyrosine Kinase Inhibitors
  • Immunomodulators
  • Cytotoxic Agents
  • Retail & Specialty Pharmacies
  • Online Pharmacies

End user

  • Specialty Cancer Centers
  • Targeted Therapy
  • Chemotherapy
  • Immunotherapy
  • Academic Research Institutes
  • Homecare Settings

Type

  • Soft Tissue Sarcoma
  • Leiomyosarcoma
  • Liposarcoma
  • Synovial
  • Bone Sarcoma
  • Osteosarcoma
  • Ewing Sarcoma
  • Chondrosarcoma

Treatment

  • Targeted Therapy
  • TKIs Inhibitors
  • mTOR Inhibitors
  • Chemotherapy
  • Anthracyclines
  • Alkylating Agents
  • Immunotherapy
  • PD-1/PD-L1 Inhibitors
  • CAR-T

Drug Class

  • Tyrosine Kinase Inhibitors
  • Immunomodulators
  • Cytotoxic Agents

Disease Indication

  • Malignant bone tumors
  • Soft tissue sarcoma
  • Dermatofibro sarcoma
  • Leiomyosarcoma
  • Synovial cell sarcoma
  • Rhabdomyo sarcoma
  • Others
Vishnu Nair
Vishnu Nair
Head - Global Business Development

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Sarcoma Drugs Market - Regional Analysis

North America Market Insights

North America in the sarcoma drugs industry is projected to emerge as the dominating region, garnering the largest share of 42.5% by the end of 2035. The market’s upliftment in the region is highly attributed to its leadership, administrative benefits, R&D investments, an increase in healthcare expenditure, and the availability of clinical trial facilities. According to the January 2022 Research America Organization report, 75% of the overall population readily supports doubled federal government expenditure for conducting thorough medical research, while 85% of the population in the U.S. favors federal government investment. In addition, R&D-based investments for medical and health, particularly in the U.S., increased to USD 245.1 billion, thereby denoting an 11.1% rise from previous years, which is suitable for the market’s growth.

The sarcoma drugs market in the U.S. is significantly growing, owing to the presence of insurance coverage services, precision medicine availability, competition in biosimilars, and an expansion in telemedicine. Additionally, government bodies are playing a crucial role in approving medicines for sarcoma, which is also fueling the market’s demand in the country. As per the April 2024 NLM article, nirogacestat was approved in 2023 by the U.S. FDA, suitable for aiding desmoid tumors. The disease incidence is 3 to 5 per 100,000 people, and the overall average wholesale price (AWP) has been set to USD 34,800. On the contrary, the medication price for a month is USD 37,285 and USD 447,428 for a year, thus contributing to the market’s development.

The market in Canada is also growing due to the provision of public healthcare investments, provincial reforms, penetration in generics, cross-border clinical trials, and indigenous health inclusion. According to the January 2023 Government of Canada report, an estimated 10,000 children in the country suffer from cancer, and only 1,500 are diagnosed. In this regard, the Canadian Institutes of Health Research (CIHR) offered USD 23 million in funding to develop the Canadian Pediatric Cancer Consortium (CPCC). In addition, the CIHR has invested USD 1 billion in cancer research over the past 5 years, along with USD 3.1 million for supporting pediatric cancer research.

Healthcare Expenditure and Components in North America

U.S.

Canada

Factors

Price/Percentage

Factors

Price/Percentage

Hospital care

USD 1,519.7 (31.2%)

Yearly healthcare spending

USD 270 billion

Other personal healthcare

USD 800.8 (16.5%)

Residential locations

750 with 6,000 family physicians

Physician Services

USD 721.7 (14.8%)

Medical services

70.9% publicly funded

Prescription drugs

USD 449.7 (9.2%)

Federal government investment

USD 196.1 billion for 10 years

Net health insurance cost

USD 302.9 (6.2%)

Working Together

to Improve Health Care for Canadians Plan

USD 200 billion for 10 years

Clinical services

USD 256.3 (5.3%)

Public sector healthcare

USD 45.9 billion through the Canada Health Transfer

Investment

USD 238.8 (4.9%)

Health and workforce planning

USD 200 billion

Sources: AMA, April 2025; CFMS, 2024

APAC Market Insights

Asia Pacific in the sarcoma drugs market is expected to emerge as the fastest-growing region, with a share of 22.3% during the projected timeline. The market’s growth in the region is propelled by a surge in the disease burden, improved healthcare accessibility, government strategies, and biosimilar integration. In this regard, the April 2025 NLM article reported that the sarcoma incidence rate in Central Asia has been 66.5% over the past 4 years, followed by 32.2% in East Asia, and 18.1% in Southeast Asia. Therefore, with the prevalence rate, there is a huge demand for sarcoma medications, along with diagnostic and treatment solutions, which is driving the market.

The sarcoma drugs market in China is steadily growing, owing to administrative support, government funding, focus on precision medicine, growth in regional pharma, treatment availability, and impact on urbanization. As per the April 2022 NLM article, a clinical study was conducted on 19 patients to determine the neoadjuvant radiotherapy usability, which is widely utilized for aiding sarcoma in the country. The study comprised 14 male and 5 females, and the objective response rate (ORR) for the treatment was 31.6%, along with 89.5% for the disease control rate (DCR). Therefore, the therapy has been proven to be successful, which is effectively contributing to the market’s growth.

The sarcoma drugs market in India is gaining increased traction, based on factors such as cost-effective generics, government programs, telehealth expansions, private and public collaborations, and a surge in sarcoma awareness. According to the August 2023 PIB Government report, generic medicines commercialized through Janaushadhi Kendras are priced at 50% to 90% less than branded medicines. As a result, the August 2024 Ministry of Health and Welfare report declared that there has been a reduction in out-of-pocket expenses by more than 40%. Additionally, the Ayushman Bharat scheme has offered insurance coverage to more than 500 million people at USD 6,000, thus suitable for the market’s development.

Europe Market Insights

Europe in the sarcoma drugs market is anticipated to hold a considerable share of 28.2% by the end of the forecast timeline. The market’s development in the region is effectively fueled by administrative harmonization, the regional health fund, and biosimilar implementation. According to the January 2025 NLM article, out of 48 new cancer drug applications, 4 (8%) were submitted to the European Medicines Agency (EMA). Furthermore, 19 drugs, which is 81%, achieved the standard marketing authorization by the EMA, and the usual approval duration is 394 to 481 days. Therefore, with the presence of such administrative bodies, there is a positive impact on the market in the overall region.

The market in Germany is gaining increased exposure, owing to the presence of universal healthcare policies, increased R&D investments, CAR-T leadership, outpatient expansion, and a surge in the aging population. As per the 2025 World Bank Group report, the present gross domestic product (GDP) based on healthcare expenditure accounts for 11.8% as of 2023. Besides, the 2025 Statistisches Bundesamt (Destatis) report indicated that the health spending in the country increased to € 474.1 billion over the past four years, denoting €5,699 per inhabitant. This was the largest increase, accounting for 7.5% per capita, thus suitable for the market’s growth opportunity.

The sarcoma drugs market in the UK is also developing due to factors, including accelerations in NICE, NIH budget prioritization, generic dominance, and telehealth service adoption. According to the November 2024 NLM data report, the sarcoma incidence for cancer is unusual in the country, with 9% of cases catering to the 30-year age group, and only 43% are a part of the 65-year age group. The prognosis is extremely poor, with an overall 54% survival rate. Therefore, the launch of sarcoma drugs through regulatory approvals is needed in the country, thereby creating an optimistic outlook for the market. The growing oncology drug pipeline and a massive patient pool have led to a high demand for vascular access devices, such as peripheral intravenous (IV) cannulas, central venous catheters (CVCs), implanted Ports (Port-a-Cath), elastomeric infusion pumps, and closed-system transfer devices (CSTDs), among several others. The dependency on multi-tiered device suits has resulted in a stronger trade scenario for medical instruments.

Medical Instruments Import and Export in Europe

Countries

Import

Export

Germany

USD 13.1 billion

USD 18.4 billion

UK

USD 4.4 billion

USD 3 billion

Netherlands

USD 14.1 billion

USD 9.3 billion

Ireland

USD 1.9 billion

USD 9.0 billion

France

USD 6.4 billion

USD 3.9 billion

Belgium

USD 4.5 billion

USD 3.3 billion

Italy

USD 4.6 billion

USD 3.1 billion

Switzerland

USD 2.9 billion

USD 4.5 billion

Poland

USD 1.7 billion

USD 1.4 billion

Spain

USD 3.3 billion

USD 802 million

Source: OEC, July 2025

Sarcoma Drugs Market Share
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Key Sarcoma Drugs Market Players:

    The international market has witnessed intense competition between specialized biotech firms and multinational pharma giants. Market leaders, such as Novartis and Bristol Myers, readily dominate with standard immunotherapies and targeted therapies, while biotech, including Adaptimmune, has pioneered the CAR-T treatment option. Besides, tactical initiatives such as expansion in emerging markets, orphan drug development, and precision medicine collaboration are effectively adopted by these organizations, thereby denoting a huge growth opportunity for the overall market.

    Here is a list of key players operating in the global market:

    Company Name

    Country

    Market Share (2024)

    Industry Focus

    Notable Products

    Bristol Myers Squibb

    U.S.

    19.5%

    Immunotherapy/TKIs

    Opdivo, Yervoy

    Novartis

    Switzerland

    16.5%

    Targeted Therapy

    Tafinlar, Mekinist

    Pfizer

    U.S.

    13.2%

    Chemotherapy

    Sutent, Inlyta

    Merck & Co.

    U.S.

    10.9%

    Immunotherapy

    Keytruda

    Roche

    Switzerland

    9.2%

    Biologics

    Tecentriq, Avastin

    Eli Lilly

    U.S.

    xx%

    TKIs

    Lartruvo, Verzenio

    Amgen

    U.S.

    xx%

    Biosimilars

    Kanjinti, Mvasi

    Sanofi

    France

    xx%

    Rare Cancers

    Jevtana, Sarclisa

    AstraZeneca

    UK

    xx%

    PARP Inhibitors

    Lynparza

    GlaxoSmithKline (GSK)

    UK

    xx%

    Immunotherapy

    Zejula

    Bayer

    Germany

    xx%

    TKIs

    Nexavar, Stivarga

    Dr. Reddy’s

    India

    xx%

    Generics

    Doxorubicin biosimilar

    Cipla

    India

    xx%

    Generics

    Imatinib generics

    Hetero Drugs

    India

    xx%

    Biosimilars

    Trastuzumab biosimilar

    BioNTech

    Germany

    xx%

    mRNA Therapeutics

    Personalized cancer vaccines

     

    Sources: BMS, Novartis, Pfizer, Merck, Roche, Lilly, Amgen, Sanofi, AZ, GSK, Bayer, Dr. Reddy’s, Cipla, Hetero, BioNTech, Takeda, Daiichi Sankyo, Astellas Pharma, Eisai, Otsuka Pharmaceutical

    Below are the areas covered for each company in the sarcoma drugs market:

    • Company Overview
    • Business Strategy
    • Key Product Offerings
    • Financial Performance
    • Key Performance Indicators
    • Risk Analysis
    • Recent Development
    • Regional Presence
    • SWOT Analysis

Recent Developments

  • In May 2024, AstraZeneca’s Imfinzi was successfully approved by the U.S. FDA for aiding adult patients with limited-stage small cell lung cancer in the U.S., receiving intense review and the Breakthrough Therapy Designation.
  • In May 2023, Sun Pharmaceutical Industries Limited entered into a licensing agreement with Philogen S.p.A for commercializing Philogen’s specialty product, Nidlegy, which is an anti-cancer biopharmaceutical.
  • Report ID: 8010
  • Published Date: Aug 20, 2025
  • Report Format: PDF, PPT
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Frequently Asked Questions (FAQ)

In the year 2025, the industry size of the sarcoma drugs market was over USD 2.1 billion.

The market size for the sarcoma drugs market is projected to reach USD 4.6 billion by the end of 2035 expanding at a CAGR of 9.2% during the forecast period i.e., between 2026-2035.

The major players in the market are BMS, Novartis, Pfizer, Merck, Roche, Lilly, and others.

In terms of the distribution channel segment, the hospital pharmacies segment is anticipated to garner the largest market share of 58.7% by 2035 and display lucrative growth opportunities during 2026-2035.

The market in North America is projected to hold the largest market share of 42.5% by the end of 2035 and provide more business opportunities in the future.
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