Knotless Tissue Control Devices Market Size & Share, by Product Type (Short-term, Long-term, Nonabsorbable polymers); Application (Hospitals, Ambulatory Surgical Centers, Trauma Centers, Medical Device Manufacturers, Pharmaceutical Companies, Research Centers, Laboratory) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2023-2033

  • Report ID: 4237
  • Published Date: Feb 20, 2023
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2023-2033

Knotless Tissue Control Devices Market size is poised to cross USD 670 Million by the end of 2033, growing at a CAGR of 4% during the forecast period, i.e., 2023-2033. In the year 2022, the industry size of knotless tissue control devices was over USD 460 Million. The primary growth factor for the knotless tissue control devices market to expand is the high number of surgeries performed worldwide. As per recent estimates done in 2020, it was revealed that around 300 million major surgeries are performed each year globally; out of which 50 million were done in the United States and 20 million in Europe. The increasing number of surgeries is attributed to rising accidents and chronic disorders. An increasing number of accidents count across the world is growing day by day with huge traffic and the negligence of people. And most of these accidents cause minor or major injuries that need surgery. Sutures are the only way to prevent the loss of blood and enhance the healing process during such situations.

Knotless tissue control devices are generally absorbable and antibacterial that are developed to facilitate soft tissue approximation. These devices provide enhanced performance characteristics and wound-holding security with added features that offer increased efficiency and control. The great advantages of knotless tissue control devices such as distribution of tension along the wound, simplified knot tying, and reduced knot-related complications, are expected to boost the demand for knotless tissue control devices in the healthcare industry. Thus, the high number of surgeons in the healthcare sector is projected to increase the adoption rate of knotless tissue control devices. As of 2022, in the United States, there were about 54,800 surgical physicians.

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Knotless Tissue Control Devices Sector: Growth Drivers and Challenges

Growth Drivers

  • Increasing number of surgeries performed are expected to boost the market – During the assessment period, a growing number of surgeries are expected to benefit the industry. In the years ahead, the industry is expected to be driven by an increase in the number of knee replacement surgery, bypass surgeries, hip replacements, and cosmetic procedures. Based on a National Centre for Biotechnology Information report, approximately 30% of elderly people fall due to difficulties moving, which is the leading cause of knee replacement surgical operations.
  • High Expenditure in the Healthcare Industry Owing to Increasing Investments – The recent data showed that the global spending on the healthcare industry was approximately USD 9 trillion in the year 2020, an increase from just USD 7 trillion in 2015. 
  • Rise in Cosmetic Surgeries with Increasing Disposable Income and Inborn Deformities – The recent statistics reveal that in the United States, approximately USD 10 billion amount of revenue was garnered through surgical cosmetic procedures in 2021. Further, the total amount of revenue generated from surgical and nonsurgical cosmetic procedures stood up at around USD 16 billion in 2021.
  • Escalation in the Number of Hospitals with Rising Concern on Healthcare - As per the Organization for Economic Co-operation and Development, the number of hospitals in the United States rose from 5,564 in 2015 to 6,090 in 2019.


  • High Surgical Site Infection - It is observed that there are possibilities for the occurrence of post-operational complications in the unidirectional knotless sutures. This will enhance the risk of surgical site infection. Also, the results are not the same in all the surgeries but there is no blood loss.
  • High Cost of Antibacterial Equipment
  • Easy Availability of Other Wound Healing Products

Knotless Tissue Control Devices Market: Key Insights

Base Year


Forecast Year




Base Year Market Size (2022)

USD 460 Million

Forecast Year Market Size (2033)

USD 670 Million

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)
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Knotless Tissue Control Devices Segmentation

The global knotless tissue control devices market is segmented and analyzed for demand and supply by application into hospitals, ambulatory surgical centers, trauma centers, medical device manufacturers, pharmaceutical companies, research centers and laboratories, and others. Out of these, the hospital segment is expected to garner the highest revenue by 2033, owing to the high number of hospitals across the world. A recent study revealed that in 2020, the hospitals in Colombia region had the highest number with 10,900 hospitals. Further, Japan had 8,240 hospitals and the United States had 6,090 hospitals in the same period. Additionally, the growing hospital industry is another growth factor expanding the market size. Hospitals increased tremendously during the pandemic and the increasing health issues that require surgery or hospitalization increased the demand for hospitals. The time of recovery from surgery is more than a week in major incidents which drives the growth of the hospital segment compared to others and is estimated to propel the growth of the market in the coming years.

The global knotless tissue control devices market is also segmented and analyzed for demand and supply by product type into short-term, long-term, and nonabsorbable polymers. Amongst these segments, the nonabsorbable polymers segment is expected to garner a significant share. The increasing number of orthopedic procedures and surgeries is estimated to drive market growth during the forecast period. Over 6 million orthopedic surgical procedures are performed every year in the United States as of 2021. Nonabsorbable polymers are used when the wound requires high tensile strength to hold to the tissue and can be easily removed from the site of surgery. Most of the wounds on the external surface of the skin require a strong tensile strength to hold the cut tissue in place during the healing process. Additionally, the removal of the sutures is helpful to avoid any foreign material attachment at the site of a wound. The presence of absorbable sutures will take a longer time to dissolve into the skin when a strong thread is used which may cause infection. While the use of nonabsorbable polymer sutures can be removed after a certain period of time and allow the tissue to heal by itself without any complications.

Our in-depth analysis of the global knotless tissue control devices market includes the following segments:

           By Product Type

  • Short-term
  • Long-term
  • Nonabsorbable polymers

          By Application

  • Hospitals
  • Ambulatory Surgical Centers
  • Trauma Centers
  • Medical Device Manufacturers
  • Pharmaceutical Companies
  • Research Centers and Laboratory
  • Others

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Knotless Tissue Control Devices Industry - Regional Synopsis

North America Market Forecast

The North American knotless tissue control devices market, amongst the market in all the other regions, is projected to hold the largest market share by the end of 2033. The growth of the market can be attributed majorly to the rising cases and deaths of chronic cases in the region. Rising chronic diseases have resulted in increased surgical sutures which in turn is projected to rise the demand for knotless tissue control devices. As per a recent study by the Centers for Disease Control and Prevention in 2022, it is revealed that 6 out of 10 adults in the U.S. have been diagnosed with one chronic disease and respectively 4 out of 10 have been diagnosed with two or more chronic diseases. Further, North America is anticipated to dominate the knotless tissue control devices market in the forecast period due to growth in GDP, health expenditure, and changing lifestyles. The Centers for Medicare & Medicaid Services also stated that in 2020, the national health expenditure in the region accounted for USD 4.1 trillion, or USD 12,530 per person. This accounted for 19.7% of the gross domestic product (GDP). Additionally, the growth in the healthcare industry is expected to increase the adoption rate of knotless tissue control devices in the hospitals of the region. As of 2021, the healthcare industry stood up at USD 810 billion in the United States.

Europe Market Forecast

Moreover, the European region is also estimated to garner a significant share during the forecast period owing to the growing healthcare industry. The rising number of investments in the healthcare sector and improvement in surgical methods and infrastructure development is anticipated to have a positive impact on market growth. It is reported that in 2020 about 1 million cesarean sections were performed in Europe as per the estimations.

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Companies Dominating the Knotless Tissue Control Devices Landscape

    • Medtronic
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Johnson & Johnson Services, Inc.
    • Medical Device Business Services, Inc. (Johnson & Johnson Services, Inc.)
    • Medline Industries, LP
    • Dalent LLC
    • Acera Surgical
    • Kerecis
    • Guard Medical Inc.
    • Axio Biosolutions Pvt Ltd
    • Grapheal
    • Smith & Nephew

In the News


  • Medical Device Business Services, Inc. has launched ECHELON 3000 Stapler. This is a digitally enabled device that will provide surgeons with simple, one-handed powered articulation and help with the needs of their patients. With the addition of a 39% greater jaw aperture and a 27% greater articulation span, ECHELON 3000 gives surgeons better access and control over each transaction, even in tight spaces and on challenging tissue.

  • Smith & Nephew has launched HEALICOIL KNOTLESS Suture Anchor, expanding its line of advanced healing solutions for rotator cuff repair.


Author Credits:  Radhika Pawar

  • Report ID: 4237
  • Published Date: Feb 20, 2023
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

The rising cases of chronic diseases across the world have increased the demand for surgical sutures which in turn is anticipated to be the primary growth factor for the expansion of the knotless tissue control devices market.

The market is anticipated to attain a CAGR of 4% over the forecast period, i.e., 2023-2033.

The availability of other would healing products coupled with high risk of on-site surgical infection and high costs of antibacterial equipment are estimated to be the growth hindering factors for the market expansion.

The market in North America is projected to hold the largest market share by the end of 2031 and provide more business opportunities in the future.

The major players in the market are Medtronic, Johnson & Johnson Services, Inc., Medical Device Business Services, Inc., Medline Industries, LP, Dalent LLC, Acera Surgical, Kerecis, Guard Medical Inc., Axio Biosolutions Pvt Ltd, Grapheal, Smith & Nephew, and others.

The company profiles are selected based on the revenues generated from the product segment, geographical presence of the company which determine the revenue generating capacity as well as the new products being launched into the market by the company.

The market is segmented by product type, application, and by region.

The nonabsorbable polymers segment is anticipated to garner the largest market size by the end of 2033 and display significant growth opportunities.
Knotless Tissue Control Devices Market Report Scope

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