Epigenetics Market Size & Share, by Therapy Type (HDAC, DNMT); Applications (Oncology, Non-Oncology); Diagnostic Technologies (DNA Methylation, CHIP, Others); End Users (Hospitals, Pharmacies, Others) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2025-2037

  • Report ID: 4874
  • Published Date: Nov 15, 2024
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2025-2037

Epigenetics Market size was valued at USD 2.36 billion in 2024 and is likely to cross USD 13.72 billion by 2037, expanding at more than 14.5% CAGR during the forecast period i.e., between 2025-2037. In the year 2025, the industry size of epigenetics is estimated at USD 2.63 billion.

With cancer becoming more common and the need for better treatments growing, scientists are looking closer at epigenetics. Epigenetic drugs hold promise for figuring out who's at risk for cancer, finding it early, and tracking how well treatment is working. This innovative approach is not confined to oncology alone; researchers are broadening the scope to include potential therapies for diseases like diabetes, infections, and cardiovascular conditions. This expanding field presents a promising avenue for investment and development in the pharmaceutical sector, highlighting a shift towards more precise and personalized medicine strategies.


Epigenetics Drugs Market
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Epigenetics Sector: Growth Drivers and Challenges

Growth Drivers

  • Rising Prevalence of Chronic Diseases - The rise in long-term illnesses like cancer, diabetes, heart issues, and brain conditions is a global concern. Drugs that work on epigenetic changes, which are tied to how these diseases develop, show promise for treatment and management. Many long-term health problems don't have true cures yet. Drugs focusing on epigenetics offer a new path by targeting the root epigenetic shifts linked to these conditions. This approach could lead to more accurate and better treatments.
  • Government Funding – Governments bodies like the National Cancer Institute (NCI) and the National Institutes of Health (NIH) back and fund work in the field of epigenetics. This help from the government and similar government groups boosts the development and testing of new epigenetic drugs and ways to test for these diseases, making the epigenetics market grow fast. State grants let research groups acquire the latest technology like next-generation sequencing and high-end data analysis tools. Government grants can help study new epigenetic drugs that are in the early stages and might be too risky for private interest and backing. This opens the door to new ways to treat diseases.
  • Rising Awareness About Epigenetics – Awareness regarding micro RNA in initiating changes in genes is pushing growth in the market for epigenetics that work on said genomes. These micro RNAs control how genes work and are tied to many illnesses, making them the primary focus for new treatments. Insights into these processes are boosting the push for more research and development in gene control science and cancer biomarkers.

Challenges

  • Investment Costs – Developing drugs that work on gene control is a lengthy and complex process. It requires a lot of academic knowledge, intricate lab work, tests, and approval steps. This process can cost a lot of money and take a significant amount of time, making it hard for small companies and researchers to bring new gene control drugs to the epigenetics market. It's a big challenge to cut down these costs while still making sure the drugs are safe and work efficiently. Finding ways to lower these costs without losing quality is a key issue in the gene control drug industry.
  • FDA Approval – While there are several promising epigenetics related researches and drugs underway globally, many of them aren’t always readily available. This is because they are pending FDA and other regulatory boards’ approval. Getting FDA approval can be a lengthy and often increase expenditure for epigenetics manufacturers and researchers.

Epigenetics Market: Key Insights

Base Year

2024

Forecast Year

2025-2037

CAGR

14.5%

Base Year Market Size (2024)

USD 2.36 billion

Forecast Year Market Size (2037)

USD 13.72 billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

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Epigenetics Segmentation

Therapy Type (HDAC, DNMT)

HDAC segment is likely to hold more than 67% epigenetics market share by 2037. It is expected to around USD 3 billion by 2037, growing at a CAGR of 8%. The growth in this sector is due to HDAC inhibitors showing great results in fighting various cancers, including blood cancers and tumors. The US FDA has given the green light to HDAC inhibitors for treating different cancers, like cutaneous T cell lymphoma (CTCL). Moreover, new methods have made HDAC inhibitors more efficient in tackling specific diseases, enhancing their performance.

Applications (Oncology, Non-Oncology)

By the end of 2037, oncology segment is projected to capture around 70% epigenetics market share. The segment growth is fueled by a rising need for drugs based on gene control in both spotting and treating cancer. This market expansion is shaped by the push towards more precise medicine and therapies aimed directly at cancer traits. This shift towards precision medicine and focused treatments spurs the necessity for gene control analysis, thus boosting the growth of the oncology application section. Meanwhile, the non-oncology application sub-segment is also on an upward trend. It expected to grow at a rate of 15.30% from 2024 to 2030. This growth reflects a broad interest in refining treatment strategies across various medical fields, emphasizing the crucial role of gene control studies in modern healthcare advancements.

Diagnostic Technologies (DNA Methylation, CHIP, Others)  

In epigenetics market, DNA methylation segment is estimated to capture over 46.8% revenue share by 2037. The segment growth is linked to the growing use of DNA methylation in drug research and production, along with the drop in genome sequencing costs, boosts market expansion. In 2024, the DNA Methylation Sequencing market stood at USD 1.21 billion and is projected to hit USD 3.6 billion by 2032, marking a CAGR of 17.3% from 2024 to 2032. Currently, the market offers several in vitro diagnostic tests that utilize DNA methylation analysis of specific genes. DNA methylation plays a crucial role in gene control as a fundamental epigenetic change. Progress in DNA methylation detection methods is making diagnostic tests more precise and sensitive, thereby improving their ability to pinpoint epigenetic changes tied to illnesses.

Our in-depth analysis of the market includes the following segments:

         Therapy Type

  • HDAC
  • DNMT

         Applications

  • Oncology
  • Non-Oncology

          Diagnostic Technologies

  • DNA Methylation
  • CHIP
  • Others

          End Users

  • Pharmacies
  • Hospitals
  • Others

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Epigenetics Industry - Regional Synopsis

North America Market Statistics

North America industry is estimated to dominate majority revenue share of 47% by 2037. The leading position of this region comes from its top-notch health care systems, key firms engaging in epigenetics research and development, and the growing use of cutting-edge molecular tech by pharmaceutical and biotech sectors. Research efforts on how microorganisms fight drugs, cancer biology, and finding new medicines outside of cancer care fuel the market's expansion in North America. The area's high-standard health care framework bolsters the growth and use of epigenetic methods and treatments. With cancer rates rising in North America, there's a pressing need for improved diagnostic methods and treatments, making epigenetics a vital part of cancer studies.

The United States leads the market in North America thanks to major industry players and heightened research activities. In 2023, the market in the U.S. was worth USD 500 million and is anticipated to grow to USD 2,050 million by 2033, reflecting the country's strong focus on cancer genomics research expected to boost epigenetics' role in studies and market size.

The Canadian market was worth about USD 800 million in 2022 and is forecasted to hit USD 2000.5 million by 2030, growing at a rate of 12% during the period. This showcases Canada's commitment to advancing in this field alongside its North American counterpart, highlighting the region's overall strength in health innovation and epigenetics research.

European Market Analysis

The European region will also encounter huge growth for the epigenetics market during the forecast period and will hold the second position due to an increase in long-lasting diseases needing exact diagnosis. It is expected to grow at a pace of 13% yearly, aiming for a value of USD 353 million in 2028 from USD 190 million in 2023. The rise in knowledge about epigenetics and its role in identifying and treating diseases boosts its market growth in Europe. Additionally, the growth is fueled by the European government's backing for biotech and research efforts.

Germany stands out in the European epigenetics scene, thanks to its large pharmaceutical companies, robust research setup, and the widespread occurrence of chronic conditions. The country places a strong focus on research concerning genetic testing markers, including DNA, histones, and non-coding RNA.

The UK's epigenetics sector was worth about USD 260.9 million in 2022 and is expected to double to USD 541.5 million by 2030, growing at a steady rate of 10% from 2023 to 2030.

Research Nester
Epigenetics Drugs Market Size
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Companies Dominating the Epigenetics Landscape

    Several large drug companies include epigenetics studies within their wider cancer or other health issue programs. Moreover, a few smaller firms dedicate their entire focus to epigenetics. These efforts reflect the rapidly evolving nature of the field and its significant potential for transforming therapeutic approaches, underscoring the critical role of both large and small entities in advancing our understanding and treatment of diseases through epigenetic science.

    • AbbVie
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • F. Hoffmann-La Roche
    • GlaxoSmithKline (GSK)
    • Incyte
    • Jazz Pharmaceuticals
    • Merck & Co.
    • Novartis
    • Pfizer
    • Bio-Techne
    • Merck KGaA

In the News

  • AbbVie - AbbVie, a leading biotech firm focused on cutting-edge research, announced that as of December 1st, 2021, VENCLEXTA® (venetoclax), a drug, is now included under the Pharmaceutical Benefits Scheme (PBS). This treatment is designated for adults battling a certain form of leukemia (acute myeloid leukemia or AML) who are unable to undergo intensive chemotherapy. AML is a rapidly spreading blood cancer impacting the bone marrow and blood system. In AML, the growth of abnormal leukemia cells outpaces healthy blood cells, hindering their essential functions, such as combating infections, oxygen transport, and bleeding control. Without prompt intervention, AML can cause severe infections and additional severe health issues.
  • GlaxoSmithKline (GSK) - IDEAYA and GSK are joining forces to craft new cancer cures through a cutting-edge method named "synthetic lethality." IDEAYA contributes three projects (MAT2A, Pol Theta, and Werner Helicase) poised to reach clinical trial stages within the next few years. These initiatives are already off to a solid start, with both the 3D structures mapped out and promising early results from animal tests for two of them (MAT2A and Pol Theta). This partnership meshes well with GSK’s strategic priority of exploiting synthetic lethality in its quest to forge novel cancer therapies.

Author Credits:  Radhika Pawar


  • Report ID: 4874
  • Published Date: Nov 15, 2024
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

In the year 2025, the industry size of epigenetics is estimated at USD 2.63 billion.

The epigenetics market size was valued at USD 2.36 billion in 2024 and is likely to cross USD 13.72 billion by 2037, expanding at more than 14.5% CAGR during the forecast period i.e., between 2025-2037. With cancer becoming more common and the need for better treatments growing, scientists are looking closer at epigenetics.

North America industry is estimated to dominate majority revenue share of 47% by 2037, due to it having the leading epigenetics research concentration.

The major players in the market are AbbVie, F. Hoffmann-La Roche, GlaxoSmithKline (GSK), Incyte, Jazz Pharmaceuticals, Merck & Co., and others.
Epigenetics Market Report Scope
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