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HEALTHCARE & PHARMACEUTICAL

Vulvar and Vaginal Atrophy (VVA) Therapy Market Analysis by Symptoms (Vaginal Dryness, Burning Sensation in the Vagina, Dyspareunia, Urinary Tract Infection, and Others); by Diagnosis (Pelvic Examination, Urine Test, and Acid Balance Test); by Treatment (Non Hormonal Therapy, Hormonal Therapy, Selective Estrogen Receptor Modulators, and Laser Therapy); and by End-User (Hospitals, Clinics, and Others) – Global Supply & Demand Analysis & Opportunity Outlook 2022- 2031

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IN THE NEWS

  • Dare Bioscience, Inc.  has announced the initiation of the DARE-VVA1’s Phase I/II trial to evaluate proprietary investigational formulation for the non-hormonal treatment of moderate to severe vulvar and vaginal atrophy (VVA). DARE-VVA1 is a new intravaginal tamoxifen product developed to treat vulvar and vaginal atrophy.
  • TherapeuticsMD, Inc. announced the approval by the U.S. Food and Drug Administration for Imvexxy 4 mcg dose. Imvexxy 4 mcg is now a commercially available drug in the United States for the treatment of dyspareunia, which is a symptom of vulvar and vaginal atrophy.

Global Vulvar and Vaginal Atrophy (VVA) Therapy Market Size, Forecast, and Trend Highlights Over 2022-2031

Vulvar-and-Vaginal-Atrophy-Therapy-Market-Demand

The global vulvar and vaginal atrophy (VVA) therapy market size is estimated to garner a moderate revenue by the end of 2031 by growing at a CAGR of ~11% over the forecast period, i.e., 2022 – 2031. Further, the market generated a modest revenue in the year 2021. The growth of the market can primarily be attributed to the rising number of cases related to the hypoestrogenism condition, known as genitourinary syndrome of menopause (also known as vulvovaginal atrophy or urogenital trophy), among women. For instance, menopausal genitourinary syndrome affects approximately 30% to 75% of postmenopausal women and can significantly impair health, sexual function, and quality of life.

Global-Vulvar-and-Vaginal-Atroph-Therapy-MarketGet more information on this report: Request Sample PDF

The prevalence of vulvar and vaginal atrophy is commonly reported in postmenopausal women. Decreased estrogen of the vulvovaginal tissue, which results in inflammation of the vagina, is described as vulvar vaginal atrophy or urogenital atrophy. The vaginal inflammation also causes thinning and shrinking of the tissues. Vaginal dryness, irritation, dyspareunia, and urgency in urination are some of the common symptoms of vulvar and vaginal atrophy. It is a chronic condition leading to distressing symptoms and gradually worsens if not treated. Suitable assistance and medical guidance are available for the treatment of VVA. With the rising awareness about VVA therapies among the female population, the vulvar and vaginal atrophy therapy market is expected to expand notably in the coming years.  According to the National Institute of Health, ~1.3 million women in the United States enter menopause each year. The age of menopause begins mostly between 51 and 52 years of age.  However, approximately 5% of women worldwide experience early menopause between the ages of 40 and 45, and 1% experience premature menopause, i.e., before the age of 40, due to sex chromosomal abnormalities, resulting in permanent ovarian failure.

Global Vulvar and Vaginal Atrophy (VVA) Therapy Market: Growth Drivers and Challenges

Growth Drivers

  • Increasing Female Geriatric Population

According to the United Nations Department of Economic and Social Affairs, World Population Ageing 2020 Highlights report, there is a rapid growth of the ageing population. An estimated 727 million people are aged 65 or more in 2020. The number is forecasted to reach over 1.5 billion people, almost more than double from 9.3% in 2020 to 16% in 2050. According to the data, on average, women live longer than men. The total ageing population comprises 55% of the female population aged 65 years and above.

  • Increasing Incidences of Breast Cancer and Uterine Cancer in Women

Breast cancer has been found to affect the body’s hormones. In women, about 67%-80% of breast cancer cases are estrogen receptor (ER) positive, while in men, around 90% and 80% are estrogen receptor (ER) and progesterone receptor (PR) positive, respectively. According to the World Health Organization (WHO), in 2020, 2.3 million women were diagnosed with breast cancer worldwide. On the other hand, according to the National Cancer Institute, as of 2022, uterine cancer represents 3.4% of all new cancer cases in the United States.

  • Increase in the Healthcare Expenditure

According to the Centers for Medicare & Medicaid Services, national health spending in the United States is expected to grow at a 5.5 percent annual rate, reaching approximately USD 6.0 trillion by the end of 2027.

  • Increasing Lifestyle Related Diseases in Women

Lifestyle diseases, associated with physical inactivity and poor diet quality, pose a significant health burden. Gestational diabetes mellitus (GDM), type 2 diabetes (DM2), and polycystic ovary syndrome (PCOS) are a few of the lifestyle-related diseases that affect women. According to the Centers for Disease Control and Prevention, PCOS is one of the most common causes of female infertility, affecting 6% to 12% (up to 5 million) of US women of reproductive age as of 2020. Certain lifestyle disorders, such as depression, insomnia, and weight gain, are also common among women.

Challenges

  • Unreported Cases of Genitourinary Syndrome of Menopause Owing to Lack of Awareness
  • Concerns about Vulvar and Vaginal Atrophy from Cancer Combination Treatments
  • Adverse Effect on the Quality of Life

The global vulvar and vaginal atrophy therapy market is segmented and analyzed for demand and supply by treatment into non hormonal therapy, hormonal therapy, selective estrogen receptor modulators (SERM), and laser therapy. Amongst these segments, the hormonal therapy segment is anticipated to garner the largest revenue by the end of 2031, backed by the growing number of cancer cases as the therapy lessens the chances of cancer recurrence. For instance, according to the Centers for Disease Control and Prevention, in 2019, around 1,368 women were diagnosed with vaginal cancer in the United States. On the other hand, most women have menopausal hormone therapy (MHT) also known as hormone replacement therapy (HRT) if they experience symptoms associated with menopause.

Major Macro-Economic Indicators Impacting the Market Growth

Global-Healthcare-Expenditure

According to the statistics by the World Health Organization, the global per capita healthcare expenditure amounted to USD 1,064.741 in the year 2017. The worldwide healthcare expenditure per person grew from USD 864.313 in 2008 to USD 1,110.841 in 2018, where the U.S. is the top country that amounted to healthcare expenditure of USD 10, 623.85 per capita in 2018. As of 2018, the domestic general government healthcare spending in the U.S. was USD 5355.79, which grew from USD 3515.82 in 2008. These are some of the factors responsible for market growth over the past few years. Moreover, as per the projections by the Centers for Medicare & Medicaid Services (CMS), the estimated average annual percent change related to National Health Expenditures (NHE) in the U.S. was 5.2% in 2020 as compared to 2019 (4.5%). Furthermore, the National Health Expenditures are projected to reach USD 6,192.5 Billion in 2028, where the per capita expenditure is estimated to touch USD 17,611 in the same year. These are notable indicators that are anticipated to create lucrative business opportunities in upcoming years.

Global Vulvar and Vaginal Atrophy (VVA) Therapy Market Regional Synopsis

Regionally, the global vulvar and vaginal atrophy therapy market is studied into five major regions including North America, Europe, Asia Pacific, Latin America and Middle East & Africa region. Amongst these markets, the market in North America is projected to hold the largest market share by the end of 2031, backed by the upsurge in the number of women suffering from pre and postmenopausal hormonal imbalances, as well as the growing number of cancer cases in the region. For instance, according to the Centers for Disease Control and Prevention, in 2019, around 5,579 women (2.6 per 100,000) were diagnosed with vulvar cancer in the United States.

The global vulvar and vaginal atrophy therapy market is further classified on the basis of region as follows:

  • North America (U.S. & Canada) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook
  • Latin America (Brazil, Mexico, Argentina, Rest of Latin America) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook
  • Europe (U.K., Germany, France, Italy, Spain, Hungary, Belgium, Netherlands & Luxembourg, NORDIC (Finland, Sweden, Norway, Denmark), Ireland, Switzerland, Austria, Poland, Turkey, Russia, Rest of Europe), Poland, Turkey, Russia, Rest of Europe) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook
  • Asia-Pacific (China, India, Japan, South Korea, Singapore, Indonesia, Malaysia, Australia, New Zealand, Rest of Asia-Pacific) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook
  • Middle East and Africa (Israel, GCC (Saudi Arabia, UAE, Bahrain, Kuwait, Qatar, Oman), North Africa, South Africa, Rest of Middle East and Africa) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook.

Market Segmentation

Our in-depth analysis of the global vulvar and vaginal atrophy (VVA) therapy market includes the following segments:

Vulvar-and-Vaginal-Atrophy-Therapy-Market-Future

Top Featured Companies Dominating the Global Vulvar and Vaginal Atrophy (VVA) Therapy Market

  • Dare Bioscience, Inc.
    • Company Overview
    • Business Strategy
    • Key Product Offerings
    • Financial Performance
    • Key Performance Indicators
    • Risk Analysis
    • Recent Development
    • Regional Presence
    • SWOT Analysis
  • Almirall, S.A
  • Viveve, Inc.
  • Lutronic
  • Venus Concept
  • ThermiGen, LLC
  • Alma Lasers
  • BTL
  • Fotona
  • TherapeuticsMD, Inc.

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