Plasma Fractionation Market size is anticipated to reach USD 37 Billion by the end of 2033, growing at a CAGR of 7% during the forecast period, i.e., 2023-2033. In the year 2022, the industry size of plasma fractionation was USD 26 Billion. The growth of the market is primarily attributed to the rising prevalence of bleeding disorders that occur when there is an issue that opposes the body’s blood clotting procedure. Based on the U. S. Centers for Disease Control estimates, there are nearly 3 million people nationwide, who have been suffering from bleeding disorders.
Immunoglobulins are derived from the fractionation of plasma and are very effective in treating various neurologic, immunologic, and hematologic diseases. Hence, the increasing prevalence of immunological diseases among the population is anticipated to increase the need for immunoglobulins & alpha-1-antitrypsin in numerous areas of medicine. In addition to that, the increased focus on characterizing and diagnosing immunodeficiency is also expected to generate a high demand for plasma fractionation in the next few years owing to the high number of diagnosed patients. Further, another major factor expected to contribute to the growth of the market is the surge in plasma collection centers across the globe. For instance, a pioneer in the creation of plasma-derived medicines, Grifols has opened its 300th plasma donation site in the United States, the second in New England and the first in the state of Massachusetts.
Growth Drivers
Challenges
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Base Year |
2022 |
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Forecast Year |
2023-2033 |
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CAGR |
~ 7% |
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Base Year Market Size (2022) |
~ USD 26 Billion |
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Forecast Year Market Size (2033) |
~ USD 37 Billion |
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Regional Scope |
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Application (Immunology, Hematology, Critical Care, Rheumatology, Neurology)
The global plasma fractionation market is segmented and analyzed for demand and supply by application into immunology, hematology, critical care, rheumatology, and neurology. Out of these, the neurology segment is anticipated to garner the largest revenue by the end of 2033, backed by increasing cases of neurological disorders such as Alzheimer, and Parkinson’s. According to the Pan America Health Organization, in 2019, neurological diseases were responsible for 533,172 deaths in the region, with men accounting for 213,129 (40%) and women accounting for 320,043 (60%). Also, the application of immunoglobulin is supposed to increase in the forecast period for treating cases of chronic inflammatory demyelinating polyneuropathy (CIDP), multifocal motor neuropathy (MMN), myasthenia gravis, and inflammatory myopathies, thus expanding the segment share in the forecast period. Also, the rise in old age patients suffering from neurological disease across the globe along with increased research activities for using IVIG for neurology indications is another factor that is considered to bring growth opportunities.
End-user (Hospitals, Clinical Research Lab, Academic Institutes)
The global plasma fractionation market is also segmented and analyzed for demand and supply by end-user in hospitals, clinical research labs, and academic institutes. Out of these, the hospitals segment is attributed generate the highest revenue during the forecast period. The major factor that is attributed to fuel the segment’s growth is the increasing adoption of plasma fractionation products in treating various disorders which includes autoimmune disease, neurological diseases, bleeding, and other disorders, along with the increased patient pool opting for plasma-derived therapies worldwide. Further, the growing number of hospitals in every region of the world and the presence of plasma donation centers in hospitals are also estimated to fuel the segment’s growth. Other growth factors for the segment development include rising investments in the hospital infrastructure, and the expansion of the healthcare sector.
Our in-depth analysis of the global market includes the following segments:
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By Application |
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By Product
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By End-User |
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North American Market Forecast
The North America plasma fractionation market, amongst the market in all the other regions, is projected to hold the largest market share by the end of 2033. The high number of hemophilic patients along with the rising prevalence of other chronic diseases in the region is considered to be the major factor for the market growth in the region. In addition, the escalation in health disorders, including severe fever with thrombocytopenia syndrome (SFTS), hemophilia, and immune deficiencies, is also considered a growth factor for the market.
Europe Market Forecast
On the flip side, the European plasma fractionation market is also estimated to garner a significant share by the end of the assessment period. The major factors for the market growth in the region are attributed to the rising cases of immunodeficiency and bleeding disorders among Europeans. For instance, the total number of patient identified with a specific PI defect increased by 45.2% in Western Europe, and by 25.7% in Eastern Europe from 2013 to 2021.Furthermore, the increased count of blood plasma collection facilities across the region, and favorable regulations from the government are further propelling the growth of the market over the assessment period in the region.
Grifols, S.A., a global healthcare company and one of the world's leading producers of plasma-derived medicines, announced the acquisition of its first donation center in Canada as part of the company's commitment to increasing access to lifesaving plasma medications in the country.
The Czech health authority SUKL has granted Biotest AG the operating license for the 12th Cara Plasma plasmapheresis center in the Czech Republic.
Author Credits: Radhika Gupta, Shivam Bhutani
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