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Perineural Therapy Market Analysis by Internal Neurostimulation Devices (Spinal Cord, Vagus Nerve, Deep Brain, Gastric Electrical, and Sacral Nerve); by Biomaterials (Nerve Conduits, and Nerve Wraps); by External Neurostimulation Devices (RES, TMS, and TENS); and by End-User (Clinics, Hospitals, and Ambulatory Surgical Centers) – Global Supply & Demand Analysis & Opportunity Outlook 2022-2031

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  • May 16, 2022: Abbott Laboratories to enter an agreement with FDA regarding the reopening of company’s Mich., Sturgis, and infant formula plant. As per the agreement, Abbott will continue to import formula from FDA-registered facility in Ireland.

  • June 14, 2021: NeuroSigma, Inc. to enter into a strategic digital health partnership with KT to develop and promote the sales of neuroelectronic ADHD within and outside of Korean borders.


Global Perineural Therapy Market Size, Forecast, and Trend Highlights Over 2022 - 2031

The global perineural therapy market is estimated to garner significant revenue by the end of 2031, by growing at a CAGR of ~6% over the forecast period, i.e., 2022 – 2031. Further, the market generated remarkable revenue in the year 2021. The increasing prevalence of different neural disorders is anticipated to propel the growth of the market during the forecast period. As per the data provided by Pan American Health Organization (PAHO), in the U.S., 533,172 individuals lost their lives due to neurological conditions, out of which, 213,129 were men and 320,043 were women in 2019.

Perineural Therapy Market

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The global perineural therapy market is further estimated to witness growth on the back of the increment in approval and launch of more enhanced drugs and other products to repair and regenerate nerves. In a study conducted by the National Library of Medicine in 2020, it was observed that around 82% meaningful recovery (MR) was obtained from mixed, sensory, and motor nerve repair having almost 70 mm gaps. There were no significant differences in MR across the nerve type, age, timetorepair, and smoking status, however, significant differences were noted by the injury type. complex injures had 74% MR as compared to lacerations 85%, and neuroma resections at 94% recovery.

Global Perineural Therapy Market: Growth Drivers and Challenges

Growth Drivers

  • Higher Prevalence of Chronic Pain in Global Population Due to Changing Lifestyle

It was observed that around 10% of the global population is affected by chronic pain summing up to approximately 60 million people. Moreover, about one in every 10 people additionally develop chronic pain every year worldwide.

Rising digitalization and technological advancement have brought a major change in the physical health of the modern population. People tend to spend more time sitting in either workplaces or educational institutions and do not indulge in physical activities. Such conditions become accountable to trigger chronic pain and other diseases, which require perineural therapy.

  • Spiking Cases of Sports Injuries Resulting in Nerve Damage

Sport injuries are a major cause of neural diseases, which require perineural therapy. Data provided by the National Safety Council stated that bicycling is one of the major causes of sports injuries. The prevalence has increased by 44% in the last decade and 1,260 deaths were noticed in 2020 due to bicycle incidents. 

  • Advancement in Modern Medical Technology 

As of 2019, the total revenue of global medical technology was estimated to be around USD 450 billion, which is estimated to cross USD 590 billion by the year 2024. Moreover, the total R&D spending over global medical technology was projected to be about USD 30 billion in 2019.

  • Increment in Global Geriatric Population

According to the data by the World Bank 747.238 million individuals were aged 65 or above in 2021 across the globe. Older adults are more prone to neural disorders and would require immediate treatment.

Population (65 years and above), 2019-2021

  • Escalating Approval and Launches of Products to Regenerate and Repair Damaged Nerves

The growing development and launch of medical technologies and drugs, such as, neurostimulator devices, is estimated to boost the market growth. The modern perineural injection has been launched in the market with 85% of effectiveness. 


  • Lack of Skilled Medical Professionals
  • Possibilities of Side Effects such as, Skin Allergy and Infection
  • Presence of Alternatives owing to the Lack of Awareness

The perineural therapy market is segmented and analyzed for demand and supply by biomaterials into nerve conduits and nerve wraps, out of which, the nerve conduits segment is set to witness noteworthy growth over the forecast period. The growth of the segment can be ascribed to rising cases of nerve damage on account of multiple causes, such as sports injuries and changing lifestyles. For instance, it has been estimated that over 100 types of nerve damage exit that require significant medical attention.

Major Macro-Economic Indicators Impacting the Market Growth

Healthcare Expenditure per Capita, (USD), 2015-2018

According to the statistics by the World Health Organization, the global per capita healthcare expenditure amounted to USD 1,064.741 in the year 2017. The worldwide healthcare expenditure per person grew from USD 864.313 in 2008 to USD 1,110.841 in 2018, where the U.S. is the top country that amounted to healthcare expenditure of USD 10, 623.85 per capita in 2018. As of 2018, the domestic general government healthcare spending in the U.S. was USD 5355.79, which grew from USD 3515.82 in 2008. These are some of the factors responsible for market growth over the past few years. Moreover, as per the projections by the Centers for Medicare & Medicaid Services (CMS), the estimated average annual percent change related to National Health Expenditures (NHE) in the U.S. was 5.2% in 2020 as compared to 2019 (4.5%). Furthermore, the National Health Expenditures are projected to reach USD 6,192.5 Billion in 2028, where the per capita expenditure is estimated to touch USD 17,611 in the same year. These are notable indicators that are anticipated to create lucrative business opportunities in upcoming years.

Global Perineural Therapy Market Regional Synopsis

Regionally, the global perineural therapy market is studied into five major regions including North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa region. Amongst these markets, the market in the North America region is projected to hold the largest market share by the end of 2031. The market is projected to witness remarkable growth on the back of a higher prevalence of sports injuries. Approximately 30 million teens participate in organized sports, out of which, around 3.5 million of them get injured annually. Hence, the market is expected to grow exponentially in the region over the forecast period.

Furthermore, the Asia Pacific region is estimated to be the second-largest shareholder in the global perineural therapy market. The growth of the market in the region can be attributed to the skyrocketing cases of Alzheimer’s diseases, dementia, and other chronic disorders. For instance, the number of people with dementia is projected to reach around 70 million by the year 2050 in the Asia Pacific region. Additionally, the rising geriatric population with severed nerves is further estimated to drive the growth of the market over the forecast period. As per the data provided by the Asian Development Bank, the number of the elderly population in Asia Pacific is stated to reach around 923 million by the year 2050. Thereby, all these factors are expected to hike the growth of the market during the forecast period.

Perineural Therapy Market Share

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The global perineural therapy market is further classified on the basis of region as follows:

  • North America (U.S. & Canada) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook
  • Latin America (Brazil, Mexico, Argentina, Rest of Latin America) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook
  • Europe (U.K., Germany, France, Italy, Spain, Hungary, Belgium, Netherlands & Luxembourg, NORDIC (Finland, Sweden, Norway, Denmark), Ireland, Switzerland, Austria, Poland, Turkey, Russia, Rest of Europe), Poland, Turkey, Russia, Rest of Europe) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook
  • Asia-Pacific (China, India, Japan, South Korea, Singapore, Indonesia, Malaysia, Australia, New Zealand, Rest of Asia-Pacific) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook
  • Middle East and Africa (Israel, GCC (Saudi Arabia, UAE, Bahrain, Kuwait, Qatar, Oman), North Africa, South Africa, Rest of Middle East and Africa) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook

Market Segmentation

Our in-depth analysis of the global perineural therapy market includes the following segments:

Market Segmentation

Top Featured Companies Dominating the Global Perineural Therapy Market

  • Boston Scientific Corporation
    • Company Overview
    • Business Strategy
    • Key Product Offerings
    • Financial Performance
    • Key Performance Indicators
    • Risk Analysis
    • Recent Development
    • Regional Presence
    • SWOT Analysis 
  • tVNS Technologies GmbH
  • Abbott Laboratories
  • NeuroSigma, Inc.
  • Axogen Corporation
  • BioWave Limited
  • Baxter Healthcare Corporation
  • LivaNova, PLC
  • Integra LifeSciences Corporation
  • Soterix Medical, Inc.


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