Non-opioid Pain Patch Market Size & Share, by Product Type (Lidocaine Patch, Diclofenac Patch, Methyl Salicylate Patch, Capsaicin Patch, Ketoprofen Patch); Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2024-2036

  • Report ID: 5423
  • Published Date: Nov 30, 2023
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2024-2036

Non-opioid Pain Patch Market size is poised to reach USD 6 Billion by the end of 2036, growing at a CAGR of 5% during the forecast period, i.e., 2024-2036. In the year 2023, the industry size of non-opioid pain patch was USD 4 Billion. The reason behind the growth is due to the growing burden of diabetes across the globe. Diabetic neuropathy may present as the initial symptom of diabetes caused by excessive blood sugar levels that harm the nerves resulting in pain and discomfort in the hands, feet, or limbs.

According to the World Health Organization (WHO), around 422 million individuals globally suffer from diabetes, and the disease is directly responsible for roughly 1.5 million fatalities annually.

The growing development of advanced products is believed to fuel the non-opioid pain patch market growth. For instance, A scientific team led by Duke University has created a biocompatible polymer patch surgical patch that dissolves after releasing non-opioid medicines and it is assumed that during the crucial period following surgery, the patch should be able to manage wound discomfort for three or four days.

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Non-opioid Pain Patch Market: Key Insights

Base Year


Forecast Year




Base Year Market Size (2023)

~ USD 4 Billion

Forecast Year Market Size (2036)

~ USD 6 Billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)
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Non-opioid Pain Patch Market: Growth Drivers and Challenges


Growth Drivers

  • Rising Trend of Minimally Invasive Procedures – Non-opioid pain patch are kind of minimally invasive treatments as they aid in administrating non-addictive pain medication by being applied to the skin similar to a bandage.
  • Growing Geriatric Population- Even though there are numerous options for pain alleviation, a large number of older persons choose not to seek therapy and opt for patch such as transdermal patch which are frequently used to address chronic pain in older adults.
  • Lately, more than 8% of the global population, are 65 years of age or older.
  • Non-Opioid Pain Patch for the Treatment of Cancer- If a doctor wants to use fewer opioids’ patients with cancer pain can safely and effectively use a lidocaine or buprenorphine patch for 3-5 days that might be able to help with pain management.


  • Presence of Other Pain Management Strategies  - Apart from non-opioid pain patch pain management techniques include at-home therapies such as yoga, psychological therapies including cognitive behavioral therapy, relaxation techniques, and meditation, mind-body techniques, massage therapy, and aqua therapy that can benefit people who suffer from low back pain, migraines, fibromyalgia, arthritis, and other chronic pain as they are simple, accessible, and safe method of managing pain that people can use in a class with an instructor or at home with online videos.
  • There are numerous drugs available to manage pain including acetaminophen a first choice for many types of pain, paracetamol which is advised as the initial medication to treat acute pain, and other medications including aspirin, ibuprofen, and naproxen that are usually used to treat minor to severe pain.
  • Furthermore, the two easiest and least expensive ways to get rid of acute and chronic pain are heat and cold therapy which also help increase blood flow and metabolism.
  • Stringent Rules & Regulations for Product Approval
  • Exorbitant Cost of Pain Patch Resulting from Disruptions in Supply Chain

Non-opioid Pain Patch Segmentation

Product Type (Lidocaine Patch, Diclofenac Patch, Methyl Salicylate Patch, Capsaicin Patch, Ketoprofen Patch)

The lidocaine patch segment is estimated to account for 69% share of the global non-opioid pain patch market by 2036 owing to the growing incidence of chronic pain. An increasing number of people worldwide are affected by chronic pain, which can endure for months or years and disrupts day-to-day activities such as working, socializing, and taking care of others.

In order to lessen the intensity of all typical pain characteristics including arthritis, disk-related pain, and chronic lower back pain, and reduce opioid use in individuals, patch such as lidocaine patch can be used which are offered in both OTC and prescription strength formulations. According to estimates, in the US more than 6% of people experienced high-impact chronic pain in 2021.

Besides this, the capsaicin patch segment in the non-opioid pain patch market is anticipated to gain a noteworthy share in the coming years. Capsaicin is the component that gives chili peppers their heat and also what gives them their burning and irritating sensation. The pepper's seeds contain a significant amount of this unusual, organic compound and the hotter a pepper is, the more capsaicin it contains which acts as a pain reliever and the main component of pepper spray.

Qutenza, a high-dose capsaicin patch that has been licensed in recent years, to treat diabetic peripheral neuropathy (DPN) of the feet and to reduce the pain associated with postherpetic neuralgia.

Distribution Channel (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies)

The online pharmacies segment in the non-opioid pain patch market is set to garner a notable share. The non-narcotic painkiller patch that are filled with painkilling medicine used for chronic painful disorders are easily accessible to the public through online pharmacies. Moreover, regardless of location, patients can acquire their pain patch from licensed pharmacists online, which not only makes purchasing more convenient nonetheless also benefits many consumers monetarily and is accompanied by a guarantee of the customer's safety and security.

Additionally, the non-opioid pain patch market from hospital Pharmacies, and retail pharmacies segment are poised to jointly hold notable shares during the forecast period. Retail pharmacies offer a large selection of prescription medications and over-the-counter pain patch to alleviate discomfort. Furthermore, hospital pharmacies frequently provide specialized services that improve patients' quality of life overall, working in tandem with doctors and other healthcare providers.

Our in-depth analysis of the global non-opioid pain patch market includes the following segments:

Product Type

  • Lidocaine Patch
  •  Diclofenac Patch
  • Methyl Salicylate Patch
  • Capsaicin Patch
  • Ketoprofen Patch

Distribution Channel

  • Hospital Pharmacies
  •  Retail Pharmacies
  •  Online Pharmacies

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Non-opioid Pain Patch Industry - Regional Synopsis

North American Market Forecast

Non-opioid pain patch market in North America is predicted to account for the largest share of 51% by 2036 propelled by the presence of key players which has led to the development of new products. For instance, in October 2020 Vizuri Health Sciences Consumer Healthcare Inc. an innovative healthcare facility in Maryland, USA, launched a groundbreaking New Pain Relief PatchBloc24 Flexi-Stretch Pain Tape with 4-way stretch fabric and potent anesthetic to numb the pain, making it perfect for use on moving joints, including elbows and knees.

European Market Statistics

The Europe non-opioid pain patch market is estimated to be the second largest, during the forecast timeframe led by a higher prevalence of stress. For instance, Greece has over 6% frequency of depression in Europe, and more than 55% of people in the country are reported to have frequent stress. This may drive the demand for non-opioid pain patch in the region since people with stress usually experience migraine which causes pain behind one eye or in the area surrounding the temples and lasts for hours or days.

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Companies Dominating the Non-opioid Pain Patch Market

    • Sanofi S.A.
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • GlaxoSmithKline Plc.
    • Pfizer Inc.
    • Clarion Brands
    • Endo Pharmaceuticals
    • TEH SENG Pharmaceutical
    • Teva Pharmaceutical Industries Ltd.
    • Teikoku Seiyaku Co. Ltd.
    • Veridian Healthcare
    • Sorrento Therapeutics (SCILEX Pharmaceuticals Inc.


In The News

  • GlaxoSmithKline Plc. Received approval from the U.S. Food and Drug Administration for Voltaren Arthritis Pain a nonsteroidal anti-inflammatory drug for the momentary alleviation of arthritis pain, and to enhance public health by expanding the range of medications to the millions of people who experience everyday joint pain from arthritis.
  • Scilex Holding Company announced to boost the production of ELYXYB to obtain, and create non-opioid painkillers to deliver fast and long-lasting migraine relief, and also allow doctors an additional tool for managing pain.

Author Credits:  Radhika Gupta, Shivam Bhutani

  • Report ID: 5423
  • Published Date: Nov 30, 2023
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

Growing burden of diabetes across the globe and The growing development of advanced products are the major factors driving the growth of the market.

The market size of non-opioid pain patch is anticipated to attain a CAGR of 5% over the forecast period, i.e., 2024-2036.

The major players in the market are GlaxoSmithKline Plc., Pfizer Inc., Hisamitsu Pharmaceutical Co., Inc., Clarion Brands, Endo Pharmaceuticals, TEH SENG Pharmaceutical, Teva Pharmaceutical Industries Ltd., Teikoku Seiyaku Co. Ltd., Veridian Healthcare, Sorrento Therapeutics (SCILEX Pharmaceuticals Inc., and others.

The lidocaine patch segment is anticipated to garner the largest market size by the end of 2036 and display significant growth opportunities.

The market in the North American region is projected to hold the largest market share by the end of 2036 and provide more business opportunities in the future.
Non-opioid Pain Patch Market Report Scope

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