Neurotrophic Keratitis Market Size & Share, by Treatment Type (Surgical Intervention, Drugs); Application (Stage I, Stage II, Stage III) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2024-2036

  • Report ID: 5557
  • Published Date: Jan 23, 2024
  • Report Format: PDF, PPT

Global Neurotrophic Keratitis Market TOC

 

  1. An Introduction to the Research Study
    1. Preface
    2. Market Taxonomy
    3. Definition of the Market and the Segments
    4. Acronyms and Assumptions
  2. The Research Procedure
    1. Sources of Data
    2. Secondary
    3. Primary
      1. Manufacturer Front
      2. Supplier/Distributor Front
      3. End-User Front
    4. Calculation and Derivation of Market Size
      1. Top-Down Approach
      2. Bottom-up Approach
  3. Recommendation by Analyst for C-level Executives
  4. An Abstract of the Report
  5. Evaluation of Market Fluctuations and Outlook
    1. Market Growth Drivers
    2. Market Growth Deflation
    3. Market Trends
      1. Manufacturer Based
      2. End-User Based
  6. Fundamental Market Prospects
    1. Strategic Competitive Opportunities
    2. Geographic Opportunities
    3. Application Centric Opportunities
  7. Regulatory & Standards Landscape
  8. Economic Outlook: Japan
  9. Recent Trends/ Developments in Global Neurotrophic Keratitis Market
  10. Technology Transition & Adoption Analysis
  11. Industry Value Chain Analysis
  12. Industry Risk Analysis
  13. Pipeline Analysis
  14. Market Unmet Needs Analysis
  15. Industry Growth Outlook
  16. Global Neurotrophic Keratitis Market Outlook
    1. Market Overview
    2. Market Value (USD Million) Current and Future Projections, 2023-2036
    3. Market Increment $ Opportunity Assessment, 2023-2036
    4. Year-on-Year (YoY) Growth Trend Analysis
    5. Global Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Treatment Type
      1. Segmentation by Drugs Market Value USD Million) Current and Future Projections, 2023-2036
        1. Artificial Tears Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Recombinant Human Nerve Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Growth Factors Eye Drops Market Value (USD Million) Current and Future Projections, 2023-2036
        4. Antibiotics Market Value (USD Million) Current and Future Projections, 2023-2036
        5. Bandage Contact Lens Market Value (USD Million) Current and Future Projections, 2023-2036
        6. Others Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Segmentation by Surgical Intervention Market Value USD Million) Current and Future Projections, 2023-2036
        1. Tarsal Plate Suture Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Amniotic Membrane Transplant Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Others Market Value (USD Million) Current and Future Projections, 2023-2036
    6. Global Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Application
      1. Stage I Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Stage II Market Value (USD Million) Current and Future Projections, 2023-2036
      3. Stage III Market Value (USD Million) Current and Future Projections, 2023-2036
    7. Global Neurotrophic Keratitis Market Segmentation Analysis (2023-2036), By Geography
      1. North America Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Europe Market Value (USD Million) Current and Future Projections, 2023-2036
      3. Asia Pacific Excluding Japan (APEJ) Market Value (USD Million) Current and Future Projections, 2023-2036
      4. Japan Market Value (USD Million) Current and Future Projections, 2023-2036
      5. Latin America Market Value (USD Million) Current and Future Projections, 2023-2036
      6. Middle East & Africa Market Value (USD Million) Current and Future Projections, 2023-2036
    8. Cross Analysis of Treatment Type w.r.to. Application (USD Million), 2023-2036
  17. North America Neurotrophic Keratitis Market Outlook
    1. Detailed Overview
    2. Market Value (USD Million) Current and Future Projections, 2023-2036
    3. North America Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Treatment Type
      1. Segmentation by Drugs Market Value USD Million) Current and Future Projections, 2023-2036
        1. Artificial Tears Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Recombinant Human Nerve Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Growth Factors Eye Drops Market Value (USD Million) Current and Future Projections, 2023-2036
        4. Antibiotics Market Value (USD Million) Current and Future Projections, 2023-2036
        5. Bandage Contact Lens Market Value (USD Million) Current and Future Projections, 2023-2036
        6. Others Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Segmentation by Surgical Intervention Market Value USD Million) Current and Future Projections, 2023-2036
        1. Tarsal Plate Suture Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Amniotic Membrane Transplant Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Others Market Value (USD Million) Current and Future Projections, 2023-2036
    4. North America Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Application
      1. Stage I Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Stage II Market Value (USD Million) Current and Future Projections, 2023-2036
      3. Stage III Market Value (USD Million) Current and Future Projections, 2023-2036
    5. North America Neurotrophic Keratitis Market Segmentation Analysis (2023-2036), By Country
      1. US Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Canada Market Value (USD Million) Current and Future Projections, 2023-2036
  18. Europe Neurotrophic Keratitis Market Outlook
    1. Detailed Overview
    2. Market Value (USD Million) Current and Future Projections, 2023-2036
    3. Europe Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Treatment Type
      1. Segmentation by Drugs Market Value USD Million) Current and Future Projections, 2023-2036
        1. Artificial Tears Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Recombinant Human Nerve Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Growth Factors Eye Drops Market Value (USD Million) Current and Future Projections, 2023-2036
        4. Antibiotics Market Value (USD Million) Current and Future Projections, 2023-2036
        5. Bandage Contact Lens Market Value (USD Million) Current and Future Projections, 2023-2036
        6. Others Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Segmentation by Surgical Intervention Market Value USD Million) Current and Future Projections, 2023-2036
        1. Tarsal Plate Suture Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Amniotic Membrane Transplant Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Others Market Value (USD Million) Current and Future Projections, 2023-2036
    4. Europe Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Application
      1. Stage I Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Stage II Market Value (USD Million) Current and Future Projections, 2023-2036
      3. Stage III Market Value (USD Million) Current and Future Projections, 2023-2036
    5. Europe Neurotrophic Keratitis Market Segmentation Analysis (2023-2036), By Country
      1. Germany Market Value (USD Million) Current and Future Projections, 2023-2036
      2. France Market Value (USD Million) Current and Future Projections, 2023-2036
      3. England Market Value (USD Million) Current and Future Projections, 2023-2036
      4. Italy Market Value (USD Million) Current and Future Projections, 2023-2036
      5. Spain Market Value (USD Million) Current and Future Projections, 2023-2036
      6. Netherlands Market Value (USD Million) Current and Future Projections, 2023-2036
      7. Russia Market Value (USD Million) Current and Future Projections, 2023-2036
      8. Rest of Europe Market Value (USD Million) Current and Future Projections, 2023-2036
  19. Asia Pacific Excluding Japan (APEJ) Neurotrophic Keratitis Market Outlook
    1. Detailed Overview
    2. Market Value (USD Million) Current and Future Projections, 2023-2036
    3. Asia Pacific Excluding Japan (APEJ) Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Treatment Type
      1. Segmentation by Drugs Market Value USD Million) Current and Future Projections, 2023-2036
        1. Artificial Tears Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Recombinant Human Nerve Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Growth Factors Eye Drops Market Value (USD Million) Current and Future Projections, 2023-2036
        4. Antibiotics Market Value (USD Million) Current and Future Projections, 2023-2036
        5. Bandage Contact Lens Market Value (USD Million) Current and Future Projections, 2023-2036
        6. Others Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Segmentation by Surgical Intervention Market Value USD Million) Current and Future Projections, 2023-2036
        1. Tarsal Plate Suture Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Amniotic Membrane Transplant Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Others Market Value (USD Million) Current and Future Projections, 2023-2036
    4. Asia Pacific Excluding Japan (APEJ) Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Application
      1. Stage I Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Stage II Market Value (USD Million) Current and Future Projections, 2023-2036
      3. Stage III Market Value (USD Million) Current and Future Projections, 2023-2036
    5. Asia Pacific Excluding Japan (APEJ) Neurotrophic Keratitis Market Segmentation Analysis (2023-2036), By Country
      1. China Market Value (USD Million) Current and Future Projections, 2023-2036
      2. India Market Value (USD Million) Current and Future Projections, 2023-2036
      3. South Korea Market Value (USD Million) Current and Future Projections, 2023-2036
      4. Australia Market Value (USD Million) Current and Future Projections, 2023-2036
      5. Singapore Market Value (USD Million) Current and Future Projections, 2023-2036
      6. Rest of APEJ Market Value (USD Million) Current and Future Projections, 2023-2036
  20. Japan Neurotrophic Keratitis Market Outlook
    1. Detailed Overview
    2. Market Value (USD Million) Current and Future Projections, 2023-2036
    3. Japan Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Treatment Type
      1. Segmentation by Drugs Market Value USD Million) Current and Future Projections, 2023-2036
        1. Artificial Tears Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Recombinant Human Nerve Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Growth Factors Eye Drops Market Value (USD Million) Current and Future Projections, 2023-2036
        4. Antibiotics Market Value (USD Million) Current and Future Projections, 2023-2036
        5. Bandage Contact Lens Market Value (USD Million) Current and Future Projections, 2023-2036
        6. Others Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Segmentation by Surgical Intervention Market Value USD Million) Current and Future Projections, 2023-2036
        1. Tarsal Plate Suture Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Amniotic Membrane Transplant Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Others Market Value (USD Million) Current and Future Projections, 2023-2036
    4. Japan Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Application
      1. Stage I Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Stage II Market Value (USD Million) Current and Future Projections, 2023-2036
      3. Stage III Market Value (USD Million) Current and Future Projections, 2023-2036
  21. Latin America Neurotrophic Keratitis Market Outlook
    1. Detailed Overview
    2. Market Value (USD Million) Current and Future Projections, 2023-2036
    3. Latin America Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Treatment Type
      1. Segmentation by Drugs Market Value USD Million) Current and Future Projections, 2023-2036
        1. Artificial Tears Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Recombinant Human Nerve Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Growth Factors Eye Drops Market Value (USD Million) Current and Future Projections, 2023-2036
        4. Antibiotics Market Value (USD Million) Current and Future Projections, 2023-2036
        5. Bandage Contact Lens Market Value (USD Million) Current and Future Projections, 2023-2036
        6. Others Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Segmentation by Surgical Intervention Market Value USD Million) Current and Future Projections, 2023-2036
        1. Tarsal Plate Suture Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Amniotic Membrane Transplant Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Others Market Value (USD Million) Current and Future Projections, 2023-2036
    4. Latin America Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Application
      1. Stage I Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Stage II Market Value (USD Million) Current and Future Projections, 2023-2036
      3. Stage III Market Value (USD Million) Current and Future Projections, 2023-2036
  22. Latin America Neurotrophic Keratitis Market Segmentation Analysis (2023-2036), By Country
    1. Brazil Market Value (USD Million) Current and Future Projections, 2023-2036
    2. Mexico Market Value (USD Million) Current and Future Projections, 2023-2036
    3. Argentina Market Value (USD Million) Current and Future Projections, 2023-2036
    4. Rest of Latin America Market Value (USD Million) Current and Future Projections, 2023-2036
  23. Middle East & Africa Neurotrophic Keratitis Market Outlook
    1. Detailed Overview
    2. Market Value (USD Million) Current and Future Projections, 2023-2036
    3. Middle East & Africa Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Treatment Type
      1. Segmentation by Drugs Market Value USD Million) Current and Future Projections, 2023-2036
        1. Artificial Tears Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Recombinant Human Nerve Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Growth Factors Eye Drops Market Value (USD Million) Current and Future Projections, 2023-2036
        4. Antibiotics Market Value (USD Million) Current and Future Projections, 2023-2036
        5. Bandage Contact Lens Market Value (USD Million) Current and Future Projections, 2023-2036
        6. Others Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Segmentation by Surgical Intervention Market Value USD Million) Current and Future Projections, 2023-2036
        1. Tarsal Plate Suture Market Value (USD Million) Current and Future Projections, 2023-2036
        2. Amniotic Membrane Transplant Market Value (USD Million) Current and Future Projections, 2023-2036
        3. Others Market Value (USD Million) Current and Future Projections, 2023-2036
    4. Middle East & Africa Neurotrophic Keratitis Market Outlook & Projections, Opportunity Assessment by Segment, 2023-2036, By Application
      1. Stage I Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Stage II Market Value (USD Million) Current and Future Projections, 2023-2036
      3. Stage III Market Value (USD Million) Current and Future Projections, 2023-2036
    5. Middle East & Africa Neurotrophic Keratitis Market Segmentation Analysis (2023-2036), By Country
      1. Combined Gulf Countries Market Value (USD Million) Current and Future Projections, 2023-2036
      2. Israel Market Value (USD Million) Current and Future Projections, 2023-2036
      3. South Africa Market Value (USD Million) Current and Future Projections, 2023-2036
      4. Rest of MEA Market Value (USD Million) Current and Future Projections, 2023-2036
  24. Competitive Model: A Detailed Inside View for Investors
    1. Company Market Share (2022)
    2. Business Profile of Key Enterprise
      1. Dompé
      2. Oyster Point Pharma, Inc.
      3. Neuroptica, Inc.
      4. Recordati Rare Diseases
      5. KALA BIO
      6. ReGenTree, LLC
      7. BRIM Biotechnology, Inc.
      8. Bausch + Lomb Incorporated
      9. Oculis
      10. HLB Therapeutics

Global Market Size, Forecast, and Trend Highlights Over 2024-2036

Neurotrophic Keratitis Market size is estimated to reach USD 1.45 Billion by the end of 2036, growing at a CAGR of 17.07% during the forecast period, i.e., 2024-2036. In the year 2023, the industry size of neurotrophic keratitis was USD 192.54 Million. As one age, the prevalence rate of neurotrophic keratitis rises, which is attributed to boosting the market’s growth. The World Health Organization predicts that by 2030, one in six persons will be 60 years of age or older. By this time, there will be 1.4 billion people in the world who are 60 years of age or older, up from 1 billion in 2020. The number of individuals in the globe who are 60 years of age or older will have doubled to 2.1 billion by 2050. The population of those 80 years of age and older is predicted to treble, to 426 million, between 2020 and 2050.

In addition to these, as the first medication to treat neurotrophic keratitis, a rare corneal illness, the FDA has approved Oxervate. In clinical trials, compared to 28/5 without cenegermin, 70% of patients treated with oxycontin had full corneal healing in eight weeks. Ocular hypermia, eye inflammation, eye discomfort, and increased lacrimation are typical adverse effects. Oxervate was designated as an Orphan Drug and a Priority Review drug, respectively, indicating that it could help treat a rare disease and make a major improvement. The approval for Dompe Farmaceutici SpA was given. This highlights the industry's dedication to meeting unmet medical needs by offering incentives for the development of medications aimed at uncommon diseases.


Neurotrophic Keratitis Market
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Neurotrophic Keratitis Market: Key Insights

Base Year

2023

Forecast Year

2024-2036

CAGR

17.07%

Base Year Market Size (2023)

USD 192.54 Million

Forecast Year Market Size (2036)

USD 1.45 Billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)
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Neurotrophic Keratitis Sector: Growth Drivers and Challenges

Market-Growth-Drivers

Growth Drivers

  • Increasing Prevalence and Incidence of Neurotrophic Keratitis- Reduced or absent corneal feeling is a rare but significant eye illness called neurotrophic keratitis, which can potentially cause problems and hinder corneal healing. Numerous variables, such as environmental changes, and lifestyle modifications, may contribute to the surge. For instance, the World Health Organization predicts that between 2015 and 2050, the proportion of adults over 60 will nearly double, from 12% to 22% worldwide. The increasing number of people afflicted with neurotrophic keratitis has led to an increased need for medical interventions, including medication, therapeutic techniques, and diagnostic technologies. Due to the opportunity this rising demand presents for academics, pharmaceutical firms, and healthcare providers to develop and provide solutions, the neurotrophic keratitis market is expected to grow.
  • Upsurge in the Demand for Novel Therapies and Treatment- One of the biggest developments for patients with neurotrophic keratitis, according to an optometrist at Phoenix Eye Care and the Dry Eye Center of Arizona, is the recent discovery of Oxervate, which has completely changed the way that patients are treated. The FDA approved oxycodone in 2018 as the first medication prescribed exclusively for the treatment of neurotrophic keratitis. Alternatively, rather than treating the fundamental cause of neurotrophic keratitis, other therapy methods concentrate on stabilizing the condition and halting its progression.
  • Increasing R&D Expenditure in Healthcare- Two more reasons propelling neurotrophic keratitis market growth are rising spending on the development of healthcare infrastructure and a rise in the demand for innovative cures and treatments. Research America, for instance, reports that investments in medical and health research and development (R&D) in the United States reached USD 245.1 billion in 2020, an increase of 11.1% from 2019. Since 2015, the amount spent on eye health in Australia has grown both overall and as a proportion of GDP. Eye care accounted for USD 2.28 billion, or 2.5 percent, of all health expenditures. With 85.6% of all eye health spending going toward those over 50, this spending is concentrated in older groups. More funds for research and development enable the investigation of cutting-edge medicines, new treatment choices, and sophisticated diagnostic equipment tailored to neurotrophic keratitis. This increased emphasis on searching may result in the creation of more potent medications, focused therapies, and better patient results. All things considered, the increase in healthcare spending raises the possibility of discoveries that may benefit the neurotrophic keratitis industry.

Challenges

  • Stringent Regulations for Drug Approval by Regulatory Bodies- Drug approval is a complicated procedure that needs to be carefully reviewed by specialists in several fields, including clinical, statistical, quality, and regulatory. Staff members of the agency collaborate and iteratively work with the requestor to direct the drug development process. Without an accurate means of measurement, a medication cannot be certified. For example, OCS-01 is an experimental medication that has not been approved by any regulatory body for use in commerce in any nation. GMP regulations must be followed by pharmaceutical producers to guarantee that medications are regularly made and monitored per quality requirements. Strict legal procedures and prerequisites for medication authorization may impede the release of novel treatments onto the market.
  • The lack of standardized diagnostic instruments and the difficulty of detecting neurotrophic keratitis could cause treatment delays and impede neurotrophic keratitis market expansion.
  • The market may be at risk due to the long surgical timespan involved in direct surgical approaches like ipsilateral supraorbital/supratrochlear nerve direct negotiation, which appear to have several drawbacks, including the possibility of significant scarring, baldness, and subgaleal hematoma.


Neurotrophic Keratitis Segmentation

Treatment Type (Surgical Intervention, Drugs)

The drugs segment in the neurotrophic keratitis market is the largest and is expected to reach USD 1.06 billion by 2036, rising at a substantial CAGR of 17.19% between 2024 and 2036. In 2023, the segment was worth USD 138.69 million. The market for neurotrophic keratitis is defined by a variety of medications created to handle the particular difficulties this illness presents. In all stages of NK, artificial tears are the primary line of treatment. Similar tasks are carried out by a variety of formulations based on polymers without preservatives. Elevated lubrication facilitates epithelialization by decreasing proinflammatory cytokine levels on the eye surface and the shear pressures produced by blinking. To treat the underlying cause of neurotrophic keratitis, nerve growth factor stimulators work to encourage the growth and healing of corneal nerves.

Application (Stage I, Stage II, Stage III)

Neurotrophic keratitis market from the stage II segment was assessed at USD 66.48 million in 2023 and is expected to have a value of USD 499.35 million by 2036, rising at a substantial CAGR of 17.02% over the projected time frame. The goal of stage II therapy is to encourage PED repair and stop a corneal ulcer from forming. Treatment options include amniotic membrane grafting, topical autologous serum application, lubricating ointments, therapeutic soft contact lenses or patching, tarsorrhaphy or botulinum-induced ptosis, and topical recombinant human nerve growth factor therapy. To fight bacterial infections, doctors can give antibiotic eye drops. Although topical corticosteroids may cause stromal melting, they can be used with caution to reduce inflammation.

Our in-depth analysis of the global market includes the following segments:

        Treatment Type

  • Drugs
  • Surgical Intervention

         Application

  • Stage I
  • Stage II
  • Stage III

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Neurotrophic Keratitis Industry - Regional Synopsis

North American Market Forecast

The neurotrophic keratitis market in North America is projected to be the largest with the largest revenue of USD 458.34 million by the end of 2036 by growing at a CAGR of 17.16% over the forecast period. The market for neurotrophic keratitis is growing in North America because to the dominance of large players in the region and the increasing number of new product launches. Moreover, congenital conditions, herpes simplex infections, chemical or thermal burns, diabetes, cranial nerve injury, and chronic conditions of the ocular surface are common causes of neurotrophic keratopathy. In 2021, 29.7 million Americans of all ages (8.9% of the US population) had been diagnosed with diabetes, according to the CDC, and by the time they reach their fifth decade of life, about 12% of Americans had tested positive for HSV-2. Effective therapies are in higher need as the prevalence of these causal variables increases and incidences of neurotrophic keratitis rise.

APAC Market Statistics

The Asia Pacific neurotrophic keratitis market is estimated to be the second-largest by developing at a CAGR of 17.65% during the forecast period. The Asia Pacific market is expected to be worth USD 401.59 million by the end of 2036, up from USD 49.87 million in 2023. The focus on early detection and cutting-edge treatment options for eye illnesses is growing in the region's healthcare system. The market is growing as a result of factors like increased healthcare spending, bettering medical infrastructure, and a rise in R&D activity. The need for healthcare is also growing since those over 65 are quickly making up a greater share of the population in Southeast Asia (especially in the more populous countries of Indonesia, Vietnam, Thailand, and the Philippines), China, and India. The percentage of adults in ASEAN countries who are 60 years of age or older was 9.8% in 2017, and according to WHO estimates, that number is projected to increase to 13.7% in 2030 and 20.3% by 2050.

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Neurotrophic Keratitis Market Size
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Companies Dominating the Neurotrophic Keratitis Landscape

top-features-companies
    • Dompe Farmaceutici SpA
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Oyster Point Pharma, Inc.
    • Neuroptica, Inc.
    • Recordati Rare Diseases
    • KALA BIO
    • ReGenTree, LLC
    • BRIM Biotechnology, Inc.
    • Bausch + Lomb Incorporated
    • Oculis
    • HLB Therapeutics

In-the-news

In The News

  • BRIM Biotechnology announced that the Board of Directors approved a seasoned equity offering that will issue 20 to 22.5 million shares of new stocks priced at 60-80 New Taiwan Dollars (~USD 2-2.67 per share). A total of ~USD 40-60 million will be raised to accelerate the development of several assets within its pipeline including the current phase 3 trial of lead asset BRM421 for dry eye disease (DED) in the US and speed up the enrollment of the phase 2 trial of BRM424 for neurotrophic keratitis (NK).
  • Kala Pharmaceuticals, Inc. announced positive safety data from the first cohort of the CHASE (Corneal Healing After Secretome therapy) Phase 2b clinical trial evaluating KPI-012, a human mesenchymal stem cell secretome (MCS-S), for the treatment of persistent corneal epithelial defect (PCED). The first cohort enrolled two patients, treated with a high dose of KPI-012 (3 U/mL) four times per day (QID). Both patients successfully completed at least one week of dosing with no safety issues observed.

Author Credits:  Radhika Gupta, Shivam Bhutani


  • Report ID: 5557
  • Published Date: Jan 23, 2024
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

Increasing prevalence and incidences of neurotrophic keratitis and upsurge in demand for novel therapies and treatment are the major factors driving the market growth.

The market size of neurotrophic keratitis is anticipated to attain a CAGR of ~17.07% over the forecast period, i.e., 2024-2036.

The major players in the market are Oyster Point Pharma, Inc., Neuroptica, Inc., Recordati Rare Diseases, KALA BIO, ReGenTree, LLC, BRIM Biotechnology, Inc., Bausch + Lomb Incorporated, Oculis, HLB Therapeutics

The drugs segment is anticipated to garner the largest market size by the end of 2036 and display significant growth opportunities.

The market in the North American region is projected to hold the largest market share by the end of 2036 and provide more business opportunities in the future.
Neurotrophic Keratitis Market Report Scope
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