Cytokine Market Size & Share by Cytokine Type (Tumor Necrosis Factor-TNF, Interleukins-Il, Interferons-IFN, Epidermal Growth Factor-EGF); Therapeutic Application (Cancer, Asthma and Airway Inflammation, Arthritis); End User (Pharmaceutical & Biotechnology Companies, Contract Research Organization, Academic & Research Institutes) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2024-2036

  • Report ID: 5867
  • Published Date: Mar 11, 2024
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2024-2036

Cytokine Market size is anticipated to reach USD 750 Billion by the end of 2036, growing at a CAGR of 9% during the forecast period i.e., 2024-2036. In the year 2023, industry size of cytokine was USD 80 Billion. The growth of the market is expected to be driven by an increased incidence of cancer worldwide over the forecast period. Immunotherapies using cytokine, which are capable of regulating the immune host response to cancer cells as well as inducing tumor cell death, have been an emerging field for cancer treatment. Cancer could be a driving cause of death around the world, accounting for about 10 million deaths in 2020, or about one in six passings. The foremost common cancers are breast, lung, colon rectum, and prostate cancers.

The complex arrangement of development variables and cytokine help all tissues and organs' cellular separation and recovery. As a result, cytokine are thought to be greatly imperative in stem cell treatment. It is expected that utilizing stem cells in regenerative pharmaceuticals and specific cytokine and development components will hold noteworthy guarantees for treating numerous human illnesses. For illustration, the Boston Stem Cell Center has given stem cell treatments by combining particular cytokine, development variables, and interleukins to intercede with musculoskeletal repair. This helps in programming the repair to prepare and fitting it to the sort of sue in musculoskeletal conditions and wounds. 

Cytokine Market Overview
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Cytokine Sectors: Growth Drivers and Challenges

Growth Drivers

  • Increasing Penetration of Cytokine - The rising number of symptomatic, therapeutic, & prophylactic applications of cytokine is anticipated to move the development of the worldwide cytokine market amid the estimated period. For occurrence, in November 2021, Synthekine Inc. and Merck entered into a around the world inquire about collaboration and permit understanding to find, create, and commercialize novel cytokine therapeutics. The companies will to begin with see into potential treatments for immune system illnesses but can afterward go into immunology, oncology, and other signs. 
  • Growing Acceptance of Cytokine as Biomarkers - Cytokine are molecular messengers that allow the immune system's cells to communicate with one another and generate a coordinated, strong but independent response to target antigens. In patients with cancer, interferons and interleukins are the two types of cytokine. Cytokine are becoming more and more accepted in cancer treatment worldwide. In addition, cytokine are being used as a biomarker to diagnose the disease and this is supporting cytokine market growth.


  • High in Cost - Although cytokine have the potential to be involved in a range of applications, including cancer treatment, stem cell therapy and diagnostics, high costs associated with cytokine-based treatments and assays are expected to hamper market expansion. Cytokine tests are required for diagnosis and monitoring because cytokine play a key role in the development or regression of pathological processes, which serve as indicators on many illnesses.
  • Lack of Specificity is expected to hinder the market growth in the forecast period
  • Regulatory Obstructions Associated are set to hamper the cytokine market expansion in the upcoming period

Cytokine Market: Key Insights

Base Year


Forecast Year

2024 - 2036



Base Year Market Size (2023)

~USD 80 Billion

Forecast Year Market Size (2036)

~USD 750 Billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)
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Cytokine Segmentation

Therapeutic Application (Cancer, Asthma and Airway Inflammation, Arthritis);

In terms of therapeutic application, the cancer segment in the cytokine market is anticipated to hold 50% of the revenue share during the forecast period. There is an important role played in the development of cancer by a mixture of cytokine produced by the tumor microenvironment. Cytokine that respond to infection, inflammation, and immunity may be able to slow down the development of cancer. The growth of the market is supported by factors such as an increased incidence of cancer, research and funding for treatment. According to Globocan 2020, there were 19,292,789 new cases of cancer in the world. By 2040, this number is expected to rise to 28,887,940.In addition, cytokine market growth is boosted by the presence of competitors, product launches, collaboration and pipeline assets as well as research.

Cytokine Type (Tumor Necrosis Factor-TNF, Interleukins-Il, Interferons-IFN, Epidermal Growth Factor-EGF)

In terms of cytokine type, the tumor necrosis factor - TNF segment is in the cytokine market is anticipated to hold 40% of the revenue share during the forecast period.Tumor necrosis factor-alpha is one of the first cytokine to be discovered. When administered locally, it helps to trigger the pro-inflammatory response against pathogens and mainly affects leukocytes and vascular endothelial cells. In addition, TNF cytokine are beneficial in the case of cell apoptosis, cachexia, proliferation, differentiation, lipid metabolism and coagulation. processes. Infliximab, golimumab, etanercept, enbrel and tasonermin are some of the key TNF based medicinal products. The growth is due to an increase in the incidence of cardiovascular and oncology related diseases. TNF has been studied in a number of diseases, mainly for cardiac and cancer related indications. Many biopharmaceutical companies are associated in the research and development of TNF inhibitory medications.

Our in-depth analysis of the global cytokine market includes the following segments:

          Cytokine Type

  • Tumor Necrosis Factor-TNF
  • Interleukins-Il
  • Interferons-IFN
  • Epidermal Growth Factor-EGF

         Therapeutic Application

  • Cancer
  • Asthma and Airway Inflammation
  • Arthritis

         End User

  • Pharmaceutical & Biotechnology Companies
  • Contract Research Organization
  • Academic & Research Institutes

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Cytokine Industry - Regional Synopsis

North American Market Forecast

The cytokine market in the North America region is set to hold the largest revenue share of 35% during the forecast period. The United States is home to several publicly and privately owned businesses investing in personalized medicine, cell signaling, or other research efforts. Over the years, through microgrants, the National Institutes of Health has been supporting a number of low-scale initiatives carried out by Private Enterprises. In addition, some of the most prevalent chronic inflammatory-mediated disorders in the United States are diabetes, cardiovascular disease, arthritic and joint conditions, allergies, and chronic obstructive pulmonary disease. Because inflammation is associated with a number of disorders, major biopharma companies cooperate with many institutions or buy businesses that have extensive inflammatory product portfolios in the region.

APAC Market Statistics

The cytokine market in the Asia Pacific region is anticipated to grow significantly during the forecast period 2024-2036. In view of the increasing prevalence of chronic diseases, such as cancer, or the increased burden of cancer, the Asia Pacific region is also expected to experience strong growth in the global cytokine market. For example, cytokine therapy can help the immune system kill cancer cells or keep them from growing. As per the reports the number of people suffering from cancer is expected to grow from 26.7 million in 2021 to 29.8 million by the end of 2035.

Research Nester
Cytokine Market Size
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Companies Dominating the Cytokine Landscape

    • Sanofi
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • AbbVie Inc
    • UCB S.A
    • Novartis AG
    • Pfizer Inc.
    • Biocon Limited
    • Amgen Inc
    • GlaxoSmithKline PLC
    • General Electric Company
    • Johnson & Johnson


In The News

  • Sanofi reported that the additional Biologics License Application for Dupixentundupilumab to be used in adults with prurigo nodularis, a chronic inflammation skin disease causing extreme itch and lesions has been given priority review by the United States Food and Drug Administration. Dupixent is a fully Human Monoclonal Antibodies that inhibit the signaling of Interleukin 4 and Interleukin 13 pathways, which are not immunosuppressants.
  • Sandoz, a global leader in generic and biosimilar medicines, announced that the US Food and Drug Administration has accepted for review its supplemental Biologics License Application for a high concentration formulation of 100 mg mLHCF of its biosimilar Hyrimoz. The application includes the indications of the reference medicine Humira  not protected by orphan exclusivity, including rheumatoid arthritis, juvenile idiopathic arthritis, psoriatic arthritis, ankylosing spondylitis.

Author Credits:  Radhika Gupta, Shivam Bhutani

  • Report ID: 5867
  • Published Date: Mar 11, 2024
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

The growing prevalence of cancer and increasing research and development activities are some of the major factors anticipated to drive the growth of the cytokine market.

The market is anticipated to attain a CAGR of ~9% over the forecast period, i.e., 2024-2036.

The major players in the market are of Pfizer Inc., Biocon Limited, Amgen Inc, GlaxoSmithKline PLC, General Electric Company, Johnson & Johnson, and others.

The cancer segment is anticipated to garner the largest market size by the end of 2036 and display significant growth opportunities.

The market in North America is projected to hold the largest market share by the end of 2036 and provide more business opportunities in the future.
Cytokine Market Report Scope

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