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Methadone Market Size and Forecast, by Form (Oral Solution, Tablets, Intravenous Injections), Application (Pain Treatment, Detoxification, Maintenance Therapy, Addiction Rehabilitation), End-user (Hospital, Rehab Centers, Drug Stores, Research Centers) - Growth Trends, Key Players, Regional Analysis 2026-2035

  • Report ID: 3793
  • Published Date: Nov 20, 2025
  • Report Format: PDF, PPT

Methadone Market Outlook:

Methadone Market size was valued at USD 193.93 million in 2025 and is expected to reach USD 395.99 million by 2035, registering around 7.4% CAGR during the forecast period i.e., between 2026-2035. In the year 2026, the industry size of methadone is assessed at USD 206.85 million.

Methadone Market Size
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The growth of the market is associated with the increasing prevalence of pain after a post-surgery treatment or treatment. The demand for methadone is driven by these pain-related issues. Methadone helps in reducing the deadly pain that takes place after a therapeutic or post-surgery treatment. As per a report from the U.S. Department of Health and Human Services, in 2019, around 20% of U.S. adults suffered from chronic diseases out of which 4% of adults felt chronic pain from the disease very hard.

Additionally, the growing number of people addicted to multiple opioids such as heroin, and morphine is also a significant factor that is anticipated to drive the growth of this market in the forecast period. Methadone helps an individual get rid of the addiction or dependency on heroin, morphine, or any other prescription painkillers. As per National Survey on Drug Use and Health, indicates that around 6 million adults globally are addicted to Heroin.

Key Methadone Market Insights Summary:

  • Regional Insights:

    • By 2035, the North America methadone market is projected to secure a 42% revenue share, spurred by the rising incidence of drug addiction and the growing reliance on methadone for managing post-operative and substance-related pain.
    • The Asia Pacific region is expected to record substantial growth by 2035, supported by its expanding geriatric population that faces heightened vulnerability to chronic diseases requiring methadone-based treatments.

  • Segment Insights:

    • The oral solution segment is projected to claim the largest share by 2035 in the methadone market, bolstered by the rising geriatric demographic preference for liquid formulations amid increasing chronic disease cases.
    • The rehab center segment is expected to dominate the market by 2035, reinforced by the escalating number of individuals seeking structured rehabilitation for opioid and heroin dependence.

  • Key Growth Trends:

    • Increasing Application in Heroin Addiction Treatment
    • Increasing Geriatric Population

  • Major Challenges:

    • Side Effects of Methadone
    • Addictive Nature of Opioids

  • Key Players: Eli Lilly and Company, Sanofi S.A., Hikma Labs Inc., Mallinckrodt Pharmaceuticals, Siegfried Holding AG, Johnson Matthey, Gilead Sciences, Inc., BioControl Medical, Tianjin Central Pharmaceutical Industry Co., Ltd.

Global Methadone Market Forecast and Regional Outlook:

  • Market Size & Growth Projections:

    • 2025 Market Size: USD 193.93 million
    • 2026 Market Size: USD 206.85 million
    • Projected Market Size: USD 395.99 million by 2035
    • Growth Forecasts: 7.4%

  • Key Regional Dynamics:

    • Largest Region: North America (42% Share by 2035)
    • Fastest Growing Region: Asia Pacific
    • Dominating Countries: UUnited States, China, India, Germany, United Kingdom
    • Emerging Countries: Brazil, Mexico, Indonesia, South Korea, Turkey

    • Last updated on : 20 November, 2025

Growth Drivers

  • Increasing Application in Heroin Addiction Treatment – Methadone is widely used to reduce addiction or dependency on heroin, morphine, or prescription painkillers. Therefore, increasing application in heroin addiction treatment is one of the growth drivers of this market. As per the latest World Drug Report, every year around 35 million people suffer from Drug disorders.
  • Increasing Geriatric Population – As discussed in the above parts, methadone is a drug or medication that helps in reducing pain after a post-surgery or therapeutic treatment. Also, the medication patients recover from any kind of chronic disease if they are suffering through it. Many times it is seen that people who are above the age of 60 or who belong to the geriatric population end up suffering from chronic disease. Therefore, the increasing geriatric population is driving the growth of this market.  As per a report from the World Health Organization, the geriatric population is expected to become double.
  • Growing Development and Launches in the Field of Methadone – Recently, lots of development and launch have taken place in the field of methadone. Elite Pharmaceutical and Glenmark Pharmaceutical collaborated and introduced methadone hydrochloride tablets in the market that will be used to reduce opioid abuse in patients. 
  • Growing Existence of Chronic Diseases – In the United States around 45% population of the region suffers from chronic diseases.

Challenges

  • Side Effects of Methadone – The rise in side effects, such as constipation, nausea, and vomiting, among others, is one of the factors that is expected to restrict the expansion of the methadone market. Furthermore, the market is likely to face obstacles because of strict government approval.
  • Addictive Nature of Opioids
  • Circulation of Generic Methadone

Methadone Market Size and Forecast:

Report Attribute Details

Base Year

2025

Forecast Year

2026-2035

CAGR

7.4%

Base Year Market Size (2025)

USD 193.93 million

Forecast Year Market Size (2035)

USD 395.99 million

Regional Scope

  • North America (U.S., and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)
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Methadone Market Segmentation:

By Form Segment Analysis

The global market is segmented and analyzed for demand and supply by form into oral solutions, tablets, intravenous injections, and others. Out of this, the oral solution segment is anticipated to account for the largest market share in the forecast period. Methadone oral solution is liquid methadone that can be prescribed for pain management and addiction treatment. They come in different strengths and can be prescribed to patients who have difficulty swallowing tablets. The growth of the market can be attributed owing to the growing geriatric population suffering from chronic diseases who prefer to consume methadone in the form of an oral solution. This is anticipated drive the growth of this segment in the forecast period. For instance, as per the World Health Organization report, by 2050 the geriatric population is anticipated to grow triple from 146 million to 438 million. 

By End User Segment Analysis

The global methadone market is segmented and analyzed for demand and supply by end users in hospitals, rehab centers, drug stores, research centers, and others. The rehab center segment is estimated to hold the largest market share in the forecast period. This is attributed owing to the number of people globally suffering from heroin, drug, and morphine addiction. To cure them this addiction rehab centers widely make use of this medication. As per data, more than 3 million people are of health conditions seeking the help of rehabilitation.

Our in-depth analysis of the global market includes the following segments:

     By Form
  • Oral Solution
  • Tablets
  • Intravenous Injections
  • Others

     By Application
  • Pain Treatment
  •  Detoxification
  • Maintenance Therapy
  •  Addiction Rehabilitation
  • Others

     By End User
  • Hospital
  • Rehab Centers
  • Drug Stores
  • Research Centers
  •  Others
Vishnu Nair
Vishnu Nair
Head - Global Business Development

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Methadone Market - Regional Analysis

North American Market Insights

 North America industry is likely to account for largest revenue share of 42% by 2035, driven by increasing cases of drug addiction in the region.. According to the Centre for Disease Control and Prevalence (CDC) in 2019, 70,630 deaths were caused by drug overdose in the United States. Additionally, the increased prevalence of misery and the increase in substance abuse cases, have further fueled regional expansion. High distress is also associated with an increase in the number of patients using methadone to treat persistent post-operative pain.

APAC Market Insights

On the other, the market in the Asia-Pacific region is expected to have significant growth in the forecast period. This is owing to the fact that India and China are countries that have high populations, especially geriatric ones. This indicates that people in these countries have chances to get affected by chronic diseases which in turn will drive the growth of the market in the upcoming time.

Europe Market Insights

The market in the Europe region is estimated to have steady growth in the forecast period. This is ascribed owing to the high obtainment of analgesics. Factors such as the high population suffering from chronic and respiratory diseases in this region are driving the growth of this market in the European region. As discussed in the previous part that methadone helps to treat quite a lot of chronic diseases as well as gives relief to deadly pain the body is suffering from.

Methadone Market Share
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Methadone Market Players:

    • Eli Lilly and Company
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Sanofi S.A.
    • Hikma Labs Inc.
    • Mallinckrodt Pharmaceuticals
    • Siegfried Holding AG
    • Johnson Matthey
    • Gilead Sciences, Inc.
    • BioControl Medical
    • Tianjin Central Pharmaceutical Industry Co., Ltd.

Recent Developments

  • Novartis AG will present more than 150 abstracts that highlight the outcomes of research efforts to target disease pathways. These abstracts include updated data in ALK+ non-small cell lung cancer and the first-ever presentations of key data in polycythemia vera, multiple myeloma (blood), and locally advanced or metastatic basal cell carcinoma (skin).
  • Siegfried Holding AG inaugurates a state-of-the-art Development Center for Drug Products in Barcelona, including dedicated facilities for highly potent Drug Products.  The Development Center provides a wide range of development services and flexible pilot capacities, strengthening Siegfried's global Drug Products network. The opening concludes the successful integration of the two pharmaceutical manufacturing sites in Spain which were acquired by Siegfried beginning of 2021.
  • Report ID: 3793
  • Published Date: Nov 20, 2025
  • Report Format: PDF, PPT
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Frequently Asked Questions (FAQ)

In the year 2026, the industry size of methadone is assessed at USD 206.85 million.

The global methadone market size was valued at more than USD 193.93 million in 2025 and is expected to register a CAGR of over 7.4%, exceeding USD 395.99 million revenue by 2035.

North America methadone market is projected to secure a 42% revenue share, spurred by the rising incidence of drug addiction and the growing reliance on methadone for managing post-operative and substance-related pain.

Key players in the market include Eli Lilly and Company, Sanofi S.A., Hikma Labs Inc., Mallinckrodt Pharmaceuticals, Siegfried Holding AG, Johnson Matthey, Gilead Sciences, Inc., BioControl Medical, Tianjin Central Pharmaceutical Industry Co., Ltd.

Methadone Market Report Scope

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