Ibuprofen API Market Size & Share, by Application (Headache, Arthritis); End-User (CROs & CMOs, Pharmaceutical & Biopharmaceutical Companies) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2024-2036

  • Report ID: 5471
  • Published Date: Dec 22, 2023
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2024-2036

Ibuprofen API Market size is projected to cross USD 11 Billion by the end of 2036, growing at a CAGR of 3% during the forecast period, i.e., 2024-2036. In the year 2023, the industry size of ibuprofen API was about USD 6 billion. The growth of the market is poised to be dominated by a surge in prevalence of influenza. For instance, according to the prediction of WHO every year, there are approximately a billion instances of seasonal influenza, with 3–5 million of those instances resulting in serious disease. Hence, ibuprofen API used with a mixture of acetaminophen is set to be increased to tackle this issue. These medications can relieve headaches and muscle aches in addition to lowering temperature. 

Additionally, the rise in COVID-19 cases is also projected to have a great influence on the ibuprofen API market over the coming years. Despite being primarily a respiratory illness, COVID-19 may demand a long time to be identified and require self-administered symptomatic treatment of its subtle and non-specific clinical course. Since one of the most typical signs of COVID-19 is fever, antipyretic drugs like ibuprofen are crucial for managing patients' symptoms.

Ibuprofen API Market
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Ibuprofen API Market: Key Insights

Base Year


Forecast Year




Base Year Market Size (2023)

~ USD 6 Billion

Forecast Year Market Size (2036)

~ USD 11 Billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)
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Ibuprofen API Market: Growth Drivers and Challenges


Growth Drivers

  • Growth in Number of Women Menstruating - Approximately 1.8 billion people worldwide experience menstruation each month, which corresponds to 800 million women and girls experiencing menstruation daily, or 26 percent of the world's population. However, menstruation also brings in excessive pain. Dysmenorrhea, or period pain and cramps, are common. Most women and girls endure pain during their menstrual cycle, however to various degrees of severity. Some women experience such severe pain which further limits their physical activity. The womb frequently creates an excessive amount of the chemical messenger prostaglandin in women experiencing severe menstrual discomfort. This causes excruciating lower abdominal pains which may also hurt the thighs or back. Hence, ibuprofen is frequently employed to treat period discomfort. This pharmaceutical is classified as non-steroidal anti-inflammatory drugs (NSAIDs). Through this process of prostaglandin inhibition, it can alleviate the discomfort associated with menstruation.
  • Rise in Need for Growth in Drug Development - With the growing prevalence of various diseases, the demand for drugs is moving upward which is further demanding a rise in drug development. However, most of the time the cost of producing medications hinders the development. Hence, a substantial amount of the research and manufacturing activities of many pharmaceutical corporations are outsourced to drug manufacturing companies. For companies without the internal resources or funding to produce ibuprofen APIs internally, outsourcing the manufacturing process may prove beneficial. Additionally, it reduces the duration of production. Manufacturers and inventors may meet development timeframes by outsourcing ibuprofen APIs and benefiting from great supply chain efficiency.
  • Surge in Prevalence of Musculoskeletal Disorders in Pediatric - As a result of insufficient sports participation and incorrect posture, MSD issues frequently start in childhood. Musculoskeletal pain throughout childhood or adolescence raises the likelihood of developing it later in life, probably as a result of the formation of unhelpful attitudes, actions, and beliefs about the earlier pain occurrences. As a result, the demand for ibuprofen is predicted to rise. 


  • Strict Regulation on Ibuprofen API - Before approving a medicine, regulatory bodies must thoroughly review the relevant data. They examine things such as drug interactions, pharmacological information, safety, and efficacy. Drug applicants risk receiving a comprehensive response letter (CRL) or a complete denial from regulatory bodies if their product fails to satisfy any of these requirements. After obtaining a CRL, a drug applicant must offer more information regarding the medication, which could need further clinical trials and raise the medication's R&D costs. Drug candidates frequently withdraw their applications and end their drug studies. These kinds of things may hinder ibuprofen APIs from being adopted. As a result, the demand for ibuprofen API market is projected to hinder over the coming years.
  • High Price of Ibuprofen API - There may be a downturn in the market share of ibuprofen formulations (medicines) in the upcoming years due to the shortage of Ibuprofen active pharmaceutical ingredient (API) around the world, which has caused inflation.
  • Not Prevalence to Every Kind of Illness

Ibuprofen API Industry Segmentation

Application (Headache, Arthritis)

The arthritis segment in the ibuprofen API market is projected to gather the largest share of about 60% during the forecast period. This could be owing to the growing prevalence of arthritis. Millions of people globally suffer from arthritis. Approximately 1 in 5 individuals in the US have a medically diagnosed case of arthritis. Extreme joint pain brought on by arthritis may render it difficult for patients to engage in daily activities. Their ability to work, engage in healthy physical activity, and maintain their mental health may all be impacted by this. Hence, the demand for ibuprofen active pharmaceutical ingredient (API) is growing. Rheumatoid arthritis and other inflammatory arthritis can be treated with higher dosages of ibuprofen, which are prescribed. Ibuprofen is equally effective as aspirin along with other nonsteroidal anti-inflammatory medications (NSAIDs) in treating rheumatoid arthritis. Ibuprofen contrasts positively to other NSAIDs and has a tolerability and safety profile that is superior to that of aspirin. 

End-User (CROs & CMOs, Pharmaceutical & Biopharmaceutical Companies)

The pharmaceutical & biopharmaceutical companies segment is expected to hold 60% share of the global ibuprofen API market during the forecast period. There has been a surge in the development of pharmaceutical & biopharmaceutical companies due to which the development of ibuprofen API is rising. Additionally, the investment made by the government is also high in this sector which is why the manufacturing of medications is carried out at an expanded ratio. Additionally, more prevalence is given to biopharmaceutical companies as a result of the combination of biopharmaceutical products' safety, efficacy, and ability to cure illnesses that were previously incurable. For instance, ibuprofen is a class IIa medication (low solubility, high permeability) in the Biopharmaceutics Classification System (BCS) that is used as an anti-inflammatory, analgesic, and antipyretic.

Our in-depth analysis of the global ibuprofen API market includes the following segments:


  • Headache
  • Arthritis


  • CROs & CMOs
  • Pharmaceutical & Biopharmaceutical Companies

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Ibuprofen API Industry - Regional Synopsis

APAC Market Forecast

The Asia Pacific ibuprofen API market is set to generate the highest share of about 35% during the forecast period. This growth is set to be influenced by the low manufacturing cost of manufacturing medicines. India and China and two important nations which carry the least manufacturing cost in this region. Furthermore, this region is also experiencing a rise in health expenditure. The healthcare benefit cost trends in APAC increased from an average of over 5% in 2020 to close to 8% in 2021 before dropping to over 6% in 2022. It was anticipated that costs would increase to approximately 11% in 2023 from the previous year. Hence, all these factors are predicted to encourage the ibuprofen API market share in this region.

North American Market Analysis

The North America ibuprofen API market is also projected to have notable growth during the forecast timeframe. This growth of the region’s market is set to be influenced by the rising prevalence of migraine. North America’s population rigorously follows a sedentary lifestyle because of which the prevalence of migraine might be high among them. In the US, ibuprofen has been an over-the-counter (OTC) drug for 25 years. It is an effective and well-tolerated NSAID. Compared to many prescription therapies, over-the-counter (OTC) drugs are more accessible, less expensive, and have better safety profiles. Ibuprofen is a compelling option for over-the-counter management of migraine headaches. As a result, the ibuprofen API market is growing in this region.

Research Nester
Ibuprofen API Market size
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Companies Dominating the Ibuprofen API Market

    • Azelis
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Lonza
    • BIOCAUSE Inc.
    • IOL Chemicals and Pharmaceuticals Limited
    • Granules India Limited
    • Sri Krishna Pharmaceuticals Ltd.
    • Taj Pharmaceuticals Limited
    • Anantco Enterprises Pvt. Ltd.
    • Wellona Pharma


In The News

  • September 19, 2022: Azelis, a prominent worldwide innovation service provider in the food additives and specialty chemicals sector, is pleased to announce that it has entered into a new distribution deal with the esteemed specialty chemical manufacturer Clariant. Customers of Azelis in Austria, Germany, and Switzerland now have instant access to the whole line of active pharmaceutical ingredients (API) and excipients from Clariant.
  • March 8, 2022: At its active pharmaceutical ingredients (API) manufacturing facility in Nansha, China, Lonza, a global manufacturing partner to the biotech, nutrition, and pharmaceutical industries, today announced the completion of a laboratory expansion. With regard to the clinical supply of highly-potent APIs (HPAPI), the expansion primarily aimed to increase the capabilities and capacity of development laboratories and kilogram-scale cGMP manufacturing laboratories.

Author Credits:  Radhika Gupta, Shivam Bhutani

  • Report ID: 5471
  • Published Date: Dec 22, 2023
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

The major factors driving the growth of the market are growth in number of women menstruating, rise in need for growth in drug development, and surge in prevalence of musculoskeletal disorders in pediatrics.

The market size of ibuprofen API is anticipated to attain a CAGR of 3% over the forecast period, i.e., 2024-2036.

The major players in the market are Azelis, Lonza, BIOCAUSE Inc., IOL Chemicals and Pharmaceuticals Limited and others.

The arthritis segment is anticipated to garner the largest market size by the end of 2036 and display significant growth opportunities.

The market in the Asia Pacific region is projected to hold the largest market share by the end of 2036 and provide more business opportunities in the future.
Ibuprofen API Market Report Scope

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