Histamine Toxicity Market size is anticipated to cross USD 2 Billion by the end of 2036, expanding around 5% CAGR during the forecast period i.e., 2024-2036. In the year 2023, the industry size of histamine toxicity was over USD 400 Million. The growth in this market can be driven by an increase in consumption of seafood such as canned fish and the risk associated with its exposure to H.A.T. toxicity. According to estimates, 80% of fish consumed in the United States is imported from another country. It can also be said that the toxicity of histamine is intimately related to fish trade from all over the world.
The histamine toxicity market driven by a lack of internationally harmonized safety standards and awareness about the diseases associated with it. The development of the market for histamine toxicity is likely to be driven by a sufficient level of knowledge among food industry professionals regarding refrigeration and processing. In particular, people are not aware that expiry dates can be regarded as an important factor when buying food for cold storage. This is due to the lack of awareness, they occur more frequently in low-income countries.
Growth Drivers
Challenges
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Base Year |
2023 |
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Forecast Year |
2024 – 2036 |
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CAGR |
~5% |
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Base Year Market Size (2023) |
~USD 400 Million |
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Forecast Year Market Size (2036) |
~USD 2 Billion |
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Regional Scope |
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Drug Type (Anti-histamines and Others)
In terms of drug type, the anti-histamine segment in the histamine toxicity market is predicted to hold the highest CAGR of 90% by the end of 2036. Histamine can cause symptoms such as sneezing, coughing, and watery eyes when an individual reacts badly to allergens such as pollen, fish, and animal dander. Anti-histamines are medications used to treat allergies as well as nausea, colds, anxiety, and other symptoms. Anti-histamines mainly fall into two categories. H-1 blockers or H-1 receptor antagonists are the first category. This category of antihistamines is used to reduce allergy symptoms. H-2 blockers or H-2 receptor antagonists are the second subtype. They are used to treat gastrointestinal disorders such as motion sickness, vomiting, nausea, gastritis, stomach ulcers, and gastroesophageal reflux disease. Hence, the growing use of anti-histamine for the treatment of different symptoms, is anticipated to boost the segment’s growth.
Route of Administration (Tropical, Oral, Nasal)
Histamine toxicity market from the nasal segment is predicted to hold a significant share during the estimated period. It rarely causes side effects, apart from a possible runny nose and bitter aftertaste. If an individual’s nose becomes irritated after using the spray, they can try a moisturizing nasal gel or switch to a different nasal gel. Most allergy symptoms such as sneezing, runny nose, itching, and stuffy nose can be treated with steroid sprays. One study found that over 75% of patients with histamine intolerance reported nasal symptoms. These are very popular treatments for histamine toxicity because they work very well and have very few negative side effects. These, along with taking antihistamines, are often the doctor's first suggestion. Considering the increasing benefits of nasal sprays, this segment is expected to reach new heights during the forecast period.
Our in-depth analysis of the global histamine toxicity market includes the following segments:
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Drug Type |
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Route of Administration |
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Distribution Channel |
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North American Market Forecast
The histamine toxicity market in the North America region is set to dominate the market by registering a growth rate of 33% by the end of 2036. North American have a growing appetite for seafood with fish consumption levels exceeding the global average. This increased consumption, particularly of canned fish and certain fish species with naturally high histamine levels directly impacts the market. According to the recently published National Fisheries Institute's Top 10 List of Seafood Consumption in 2021, Americans consumed a record twenty-five pounds of fish per capita, up 1.5 pounds from 2020. Furthermore, public awareness about histamine intolerance a condition where people struggle to metabolize histamine efficiently is on the rise. This awareness creates a demand for diagnostic tests and treatments comprising digestive diamine oxidase enzyme supplements that aid in histamine breakdown.
European Market Statistics
The market in the Europe region is set to hold a significant share by the end of 2036. Due to the increased demand for frozen foods, much-canned fish is exported from Europe. The histamine toxicity market growth is to blame for all of these factors. In order to set quality standards, collaboration with the fishing community and public health authorities will be required. Besides, the European pharmaceutical and research institutions are actively engaged in developing novel treatments and diagnostics for histamine intolerance and related disorders contributing to market innovation. The availability of anti-histamines as OTC drugs in the region is also significantly driving the growth of the histamine toxicity market in the European region during the anticipated time period.
Author Credits: Radhika Gupta, Shivam Bhutani
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