CAR T-Cell Therapy Market Analysis

  • Report ID: 2441
  • Published Date: Sep 10, 2025
  • Report Format: PDF, PPT

CAR T-Cell Therapy Market Segmentation:

End use Segment Analysis

Hospitals dominate the end use segment and are set to hold a share value of 87.6% in 2035. The segment is driven by its strong infrastructure and multidisciplinary staff to take on complex treatments and effects. Hospitals offer specialized facilities, including dedicated operating theatres and an ICU, that is necessary for administering CAR T-cell therapies. In addition, the July 2022 Science Direct report illustrates that the CAR T cell infusions for the majority of patients are 88% to 98% in hospitals. The hospitals also provide ongoing monitoring of treatment to make therapy safer and more effective.

Type Segment Analysis

In the type category, CAR T cell therapy dominates the segment and is expected to hold a significant share in 2035. The segment is driven by its revolutionary outcomes in hematologic cancers, mainly in B-cell lymphomas and leukemias, where traditional therapies are ineffective. With the support of FDA approvals and strong clinical trial pipelines, CAR T-cell treatments have shown high remission rates and durability compared to other treatments. The growth of the therapy is also driven by strategic partnerships with academia, biotech, and regulatory agencies for the efficient launch of next-generation products, assuring long-term leadership in the market.

Target Antigen Segment Analysis

Based on the target antigen, the CD19 segment is predicted to capture the largest share in the market over the assessed period. The clinical validation and regulatory recognition are the drivers dominating this segment. For instance, in 2024 alone, the FDA and EMA gave clearance for six different CD19-targeted therapies. On the other hand, the NLM study published in December 2023 depicts that CAR T-cell therapy for refractory or relapsed diffuse large B-cell lymphoma (DLBCL) reports objective responses in about 70% of patients, with a specific phase II ZUMA-1 trial reporting an overall response rate (ORR) of 82% and a complete response (CR) rate of 54%, highlighting the response rate from using this technology. Moreover, its proven efficacy in treating hematologic malignancies is solidifying its dominance over other types.

Our in-depth analysis of the CAR T-cell therapy market includes the following segments:

Segment

Subsegments

Type

  • CAR T-Cell Therapy
    • CD19
    • BCMA
    • CD20
    • CD22
    • Dual Antigen (CD19/CD22)
    • Others
  • TCR Therapy
    • Others
  • TIL Therapy
    • Others

Target Antigen

  • CD19
  • BCMA
  • CD20
  • CD22
  • Dual Antigen (CD19/CD22)
  • Others

Indication

  • Acute Lymphoblastic Leukemia (ALL)
  • Large B-Cell Lymphoma (LBCL)
  • Diffuse Large B-Cell Lymphoma (DLBCL)
  • Follicular Lymphoma
  • Mantle Cell Lymphoma
  • Multiple Myeloma
  • Others

Product

  • Yescarta
  • Kymriah
  • Carvykti
  • Tecartus
  • Breyanzi
  • Abecma
  • Others

Manufacturing Process

  • Centralized Manufacturing
    • Yescarta
    • Kymriah
    • Carvykti
    • Tecartus
    • Breyanzi
    • Abecma
    • Others
  • Decentralized/Point-Of-Care Manufacturing
    • Others

End use

  • Hospitals
    • Yescarta
    • Kymriah
    • Carvykti
    • Tecartus
    • Breyanzi
    • Abecma
    • Others
  • Cancer Treatment Centers
    • Yescarta
    • Kymriah
    • Carvykti
    • Tecartus
    • Breyanzi
    • Abecma
    • Others
  • Specialty Clinics
  • Others

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

CAR T-cell therapy market size was valued at USD 6 billion in 2025.

CAR T-cell therapy market size was valued at USD 6 billion in 2025 and is projected to reach USD 45.6 billion by the end of 2035, rising at a CAGR of 22.5% during the forecast period, i.e., 2026-2035.

The major players in the market are Novartis, Gilead/Kite Pharma, Bristol Myers Squibb, Janssen (Johnson & Johnson), Legend Biotech, CARsgen, Bluebird Bio, Autolus Therapeutics, Celyad Oncology, Poseida Therapeutics, JW Therapeutics, Gracell Biotechnologies, Immuneel Therapeutics, LG Chem, Cartesian Therapeutics, Mustang Bio, CellVec, Kazia Therapeutics, Takeda, Daiichi Sankyo.

Hospitals dominate the end use segment and are set to hold a share value of 87.6% in 2035.

North America is expected to dominate the global market with a share of 48.2% by the end of 2035.
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