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Upstream Bioprocessing Equipment Market By Cell line (Microbial, Mammalian); By Processing (Single – use bioprocessing system, Continuous bioprocessing systems); By End-User (Pharmaceutical & Biological Manufacturing Companies, Research Centers) - Global Demand Analysis & Opportunity Outlook 2027

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Inflation And Looming Recession to Haunt Businesses:

In 2022 & 2023, market players expected to sail in rough waters; might incur losses due to huge gap in currency translation followed by contracting revenues, shrinking profit margins & cost pressure on logistics and supply chain. Further, U.S. economy is expected to grow merely by 3% in 2022.

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Purchasing power in the couPurchasing power in the country is expected to fell nearly by 2.5%. On the other hand, European countries to see the worst coming in the form of energy crisis especially in upcoming winters!! Right after COVID-19, inflation has started gripping the economies across the globe. Higher than anticipated inflation, especially in western world had raised concerns for national banks and financial institutions to control the economic loss and safeguard the interest of the businesses. Increased interest rates, strong USD inflated oil prices, looming prices for gas and energy resources due to Ukraine-Russia conflict, China economic slowdown (~4% in 2022) disrupting the production and global supply chain and other factors would impact each industry negatively.                                                         Request Insights

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Global Upstream Bioprocessing Equipment Market Overview

Bioprocess is a comprehensive term surrounding the R&D, assembling, and commercialization of products arranged from or utilized by natural frameworks, including fuels, food, feed, biopharmaceuticals, and cosmetics. Bio processes can be separated into upstream processes and downstream processes. The upstream procedure is portrayed as the entire procedure from early cell segregation, isolation and cultivation, to cell banking and culture extension of the cells until final harvest (end of the way of life and gathering of the live cell clump).

The Upstream process involves steps such as media development, cell culture, and development, harvesting of cells and fermentation. These processes are done under strict sterile conditions, and particular temperature and pH levels maintained throughout the process. Cell Banking is also done by upstream processes. The primary objective behind upstream processes is to provide an environment necessary for the growth of cells. This can be best done in large scale with a bioreactor which can be used for various applications such as fermentation; stem cell development; strain selection and cell-line optimization; bioprocess development; early cell screening and media selection; and producing monoclonal antibodies, vaccines and recombinant proteins.

Market Size & Forecast

Upstream bioprocessing equipment market is anticipated to record a significant CAGR over the forecast period. The increasing demand for production of therapeutic proteins, antibiotics, hormones, enzymes, blood substitutes, and vaccines are expected to increase the market demand due to the manufacturing of these products by the help of upstream bioprocessing equipment. At present the global upstream bioprocessing equipment market is observing vibrant growth owing to increasing demand of proteins due to diseases like lymphoma, rheumatoid arthritis, diabetes mellitus and growth hormone insufficiency that can be treated by specific proteins produced from bioprocesses.

On the basis of regional platform, global Upstream Bioprocessing Equipment market is segmented into five major regions including North America, Europe, Asia Pacific, Latin America and Middle East & Africa region. North-America is expected to hold a strong position in upstream bioprocessing equipment market followed by Europe. These two regions are estimated to prosper at a robust rate during the forecast year owing to large-scale use of single-use bioprocessing systems.

Asia-Pacific is estimated to be a potentially lucrative region over the forecast period. The rising diversification in the food, beverages and pharmaceutical industry in the developing regions are expected to increase the market growth. For instance, the government in some developing countries provides financial support for R&D activities which helps the industry prosper.CLICK TO DOWNLOAD FREE SAMPLE

Upstream Bioprocessing Equipment Market

Market Segmentation

Our-in depth analysis of the global Upstream Bioprocessing Equipment market includes the following segments:

By Cell line

  • Microbial
    • Bacterial
    • Yeast
    • Viral
  • Mammalian

By Processing

  • Single – use bioprocessing system
  • Continuous bioprocessing systems

By End-User

  • Pharmaceutical & Biological Manufacturing Companies
  • Research Centers

By Region

Global Upstream Bioprocessing Equipment Market is further classified on the basis of region as follows:

  • North America (United States, Canada), Market size, Y-O-Y growth Market size, Y-O-Y growth & Opportunity Analysis, Future forecast & Opportunity Analysis
  • Latin America (Brazil, Mexico, Argentina, Rest of LATAM), Market size, Y-O-Y growth, Future forecast & Opportunity Analysis
  • Europe (U.K., Germany, France, Italy, Spain, Hungary, BENELUX (Belgium, Netherlands, Luxembourg), NORDIC (Norway, Denmark, Sweden, Finland), Poland, Russia, Rest of Europe), Market size, Y-O-Y growth, Future forecast & Opportunity Analysis
  • Asia-Pacific (China, India, Japan, South Korea, Malaysia, Indonesia, Taiwan, Hong Kong, Australia, New Zealand, Rest of Asia-Pacific), Market size, Y-O-Y growth, Future forecast & Opportunity Analysis
  • Middle East and Africa (Israel, GCC (Saudi Arabia, UAE, Bahrain, Kuwait, Qatar, Oman), North Africa, South Africa, Rest of Middle East and Africa), Market size, Y-O-Y growth, Future forecast & Opportunity Analysis


Growth Drivers & Challenges

It’s been over a decade that single-use processing units have achieved thrust as it is possible to develop a small amount of drugs used for preclinical and clinical testing using these processes. As the occurrence and frequency of chronic diseases have augmented, there is a requirement to boost the production of substances to cure them. With advance in technology; well-established production systems in equipment, providing high-quality biologic drugs and increased productivity, is possible. This, in turn, increases the demand of upstream bioprocessing equipment market in biopharmaceutical industry. Besides this, upsurge in the requirement for cell therapy research, antibody production, drug discovery, monoclonal antibody and recombinant protein productions are also the major drivers for the upstream bioprocessing equipment market.

Furthermore, the presence of all systems used in bioprocessing units such as bioreactors, membrane absorbers, bioprocess containers, disposable mixers, and samplers in single-use bioprocessing units are estimated to propel the market growth. However, the requirement for skilled labor and cost constraints encountered in setting up an upstream processing unit and its maintenance along with the challenges to eliminate contamination and the space required for the setup are behaving as major restraining factors for the growth of upstream bioprocessing equipment market.

Key Players

  • GE Healthcare
    • Company Overview
    • Business Strategy
    • Key Product Offerings
    • Financial Performance
    • Key Performance Indicators
    • Risk Analysis
    • Recent Development
    • Regional Presence
    • SWOT Analysis
  • Boehringer Ingelheim Pharma GmbH & Co.KG,
  • Merck KGaA
  • Thermo Fisher Scientific
  • Katalyst Bio Engineering
  • ABEC Biopharmaceutical Manufacturing
  • Bionet Engineering
  • Lonza- Pharma & Biotech
  • Corning

Scope & Context

Overview of the Parent Market

Analyst View


The Global Upstream Bioprocessing Equipment Market is segmented as follows:

  • By Cell line Type Market Size & Y-O-Y Growth Analysis
  • By Processing Type Market Size & Y-O-Y Growth Analysis 
  • By End-User Market Size & Y-O-Y Growth Analysis
  • By Region Market Size & Y-O-Y Growth Analysis

Market Dynamics

Supply & Demand Risk

Competitive Landscape

Porter’s Five Force Model

Geographical Economic Activity

Key Players (respective SWOT Analysis) and their Strategies and Product Portfolio

Recent Trends and Developments

Industry Growth Drivers and Challenges

Key Information for Players to establish themselves in current dynamic environment

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