Tumor Necrosis Factor Inhibitor Drugs Market Analysis

  • Report ID: 6538
  • Published Date: Aug 14, 2025
  • Report Format: PDF, PPT

Tumor Necrosis Factor Inhibitor Drugs Market Segmentation:

Drug Class (Adalimumab, Etanercept, Infliximab, Golimumab, Certolizumab Pegol)

Adalimumab segment is expected to account for tumor necrosis factor inhibitor drugs market share of more than 56.3% by the end of 2035 owing to its broad application in the treatment of autoimmune illnesses, safety record, and broad efficacy. Better clinical trial outcomes, a wide range of indications, and great patient and physician familiarity are all factors contributing to the segment's growth. tumor necrosis factor inhibitor drugs market share is also increased by the continuous development of novel formulations and delivery systems.

Furthermore, adalimumab is the first and only fully human monoclonal antibody approved by the U.S FDA for the treatment of rheumatoid arthritis, used to treat a variety of inflammatory conditions in adults and children, including those brought on by autoimmune diseases. In July 2023, Sandoz announced the launch of Hyrimoz, the only adalimumab HCF biosimilar approved in the U.S.

Indication (Rheumatoid Arthritis, Psoriatic Arthritis, Crohn’s disease, Psoriasis, Ulcerative colitis, Ankylosing spondylitis, Juvenile idiopathic arthritis, Hidradenitis Suppurativa)

In tumor necrosis factor inhibitor drugs market, rheumatoid arthritis segment is set to dominate revenue share of over 42.8% by 2035 owing to the rising prevalence of rheumatoid arthritis across the globe and rising product launches. According to the Global RA Network (as referenced in health-data summaries), more than 350 million individuals worldwide had arthritis in 2021, and this number is expected to grow further due to demographic shifts such as an aging population and rising obesity rates. Adalimumab, infliximab, and etanercept are examples of TNF inhibitors that are very successful in treating RA symptoms and delaying the course of the illness.

Due to their robust clinical performance and excellent safety records, biologic medications are now the mainstay of RA treatment. For example, in December 2019, Amgen announced that its AVSOLA for moderate-to-severe rheumatoid arthritis received U.S. FDA approval.

Our in-depth analysis of the tumor necrosis factor inhibitor drugs market includes the following segments

Drug Class

  • Adalimumab
  • Etanercept
  • Infliximab
  • Golimumab
  • Certolizumab Pegol

Indication

  • Rheumatoid Arthritis
  • Psoriatic Arthritis
  • Crohn's Disease
  • Psoriasis
  • Ulcerative Colitis
  • Ankylosing Spondylitis
  • Juvenile Idiopathic Arthritis
  • Hidradenitis Suppurativa

Route of Administration

  • Subcutaneous
  • Intravenous

Distribution Channel 

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2026, the industry size of tumor necrosis factor inhibitor drugs is estimated at USD 42.78 billion.

Tumor Necrosis Factor Inhibitor Drugs Market size was over USD 41.99 billion in 2025 and is poised to exceed USD 51.69 billion by 2035, growing at over 2.1% CAGR during the forecast period i.e., between 2026-2035.

North America leads the Tumor Necrosis Factor Inhibitor Drugs Market with a 38.6% share, fueled by the presence of top pharmaceutical and biopharma companies, driving innovation and market growth through 2035.

Key players in the market include Amgen Inc., Boehringer Ingelheim Pharmaceuticals, Inc., Bio-Thera Solutions, Ltd., Janssen Biotech, Inc., Merck & Co., Inc., Pfizer Inc., Samsung Bioepis Co., Ltd., Sandoz Group AG, UCB, Inc.
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