Soft Tissue Allografts Market Analysis by Type (Cartilage, Tendon, Meniscus, Dental, Collagen, and Amniotic Allograft); by Application (Orthopedic, Dentistry, Wound Care, and Others); and by End-User (Hospitals, Orthopedic Clinics, Aesthetic Centers, Dental Clinics, and Others) – Global Supply & Demand Analysis & Opportunity Outlook 2023-2035

Buy Now Report ID: 4344 | Published Date: Feb 24, 2023

Global Soft Tissue Allografts Market Size, Forecast, and Trend Highlights Over 2023 - 2035

The global soft tissue allografts market is estimated to garner a revenue of USD 8 Billion by the end of 2035 by growing at a CAGR of ~7% over the forecast period, i.e., 2023 – 2035. Further, the market generated a revenue of USD 4 Billion in the year 2022. The growth of the market can be attributed to the increasing trauma cases related to accidents, sports injuries, and others. According to the data from 2021 from the Accident Compensation Corporation (ACC), there were roughly 692 million in injury claims related to sports and recreation. Moreover, according to the National Library of Medicine, 33 million skeletal injuries occur in the United States each year, of which 50% are tendon and ligament injuries.


In addition to these, factors that are believed to fuel the market growth of soft tissue allografts include the increasing count of anterior cruciate ligament (ACL) sprains and tears. Allograft tissue is the tissue that has been surgically implanted from one person to another. Soft tissue allografts are the replacement tissues used in an anterior cruciate ligament (ACL) to repair the damaged ligament, torn menisci, osteochondral defects, and spinal surgery. Utilization of allografts for soft tissue reconstruction results in less donor tissue site mortality and relatively short surgical time. For instance, in the United States, the prevalence rate of ACL sprains and tears ranges from 110,000 to 226,000 per year.

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Global Soft Tissue Allografts Market: Key Insights

Base Year


Forecast Year




Base Year Market Size (2022)

~ USD 4 Billion

Forecast Year Market Size (2035)

~ USD 8 Billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

Global Soft Tissue Allografts Market: Growth Drivers and Challenges


Growth Drivers

  • Growing Incidences of Sports Injuries - Sports injuries happen when exercising or playing a sport. These injuries affect the bones, muscles, tendons, ligaments, and other body structures. As per a report, in the United States, every year, approximately 4 million kids aged 14 and under suffer injuries while playing sports or engaging in leisure activities.

  • Rising Prevalence of Osteoarthritis - Older people have a higher risk to develop osteoarthritis. The breakdown of cartilage, a stretchy material that reduces the friction in joints, causes primary osteoarthritis. For instance, around 3 to 6% of people worldwide suffer from osteoarthritis. It is a cause of moderate to severe impairment in nearly 44 million people.

  • Increase in Trauma Cases – As per the World Health Organization, every year, approximately 1.3 million people's lives are ended prematurely as an outcome of a road accident. Non-fatal injuries affect between 20 and 50 million people who have become disabled as a consequence of their injury. These injuries many times cause wear and tear of bones and muscles, breaking the stability of the skeletal system.

  • Upsurge in Musculoskeletal Diseases – The musculoskeletal issues can affect the muscles, bones, and joints. The severity of MSDs can vary. In some cases, they cause pain and discomfort and in severe situations, it can lead to allografting. Musculoskeletal issues entail a variety of problems, including tendinitis, carpel tunnel syndrome, and fibromyalgia. Nearly 1.71 billion people around the world have musculoskeletal diseases

  • Technological Advancement in Allografts – The newest technology from the CYGNUS family of amniotic tissue allografts, CYGNUS Matrix Disks, was just released, by Vivex Biologics, Inc. With enhanced handling and increased workability, CYGNUS® Matrix Disks are a flexible, multi-layer allograft that preserves the amnion layer


  • High treatment cost of soft tissues - The average cost of allograft ACL restoration was around USD 5500. ACL reconstruction is a commonly practiced orthopedic operation. Though there have been many technological advancements in allography, the cost price of the operation is also increasing.  Moreover, in comparison to autografts, allografts are more expensive.
  • Shortage of skilled workers
  • Lack of medical reimbursement policies for soft tissue allografts

Market Segmentation

The global soft tissue allografts market is segmented and analyzed for demand and supply by application in orthopedics, dentistry, wound care, and others. Out of the four types of application, the dentistry segment is estimated to gain the largest market share over the projected time frame. The growth of the segment can be attributed to the rising number of tooth loss in the aging population, and tooth-related issues i.e., replacement of missing teeth in people that require effective treatment. For instance, until 2019, around 4 million people in the United States alone had dental implants, and this number is expanding by 520,000 annually.

The global soft tissue allografts market is also segmented and analyzed for demand and supply by type into cartilage allograft, tendon allograft, meniscus allograft, dental allograft, collagen allograft, and amniotic allograft. Amongst these six segments, the tendon allograft is expected to garner a significant share. The segment growth is attributed to rising cases of tendinitis and especially in older people. The most typical sites for tendinitis to develop with age include the Achilles tendon, hip, elbow, shoulder, and base of the thumb. This is due to the deterioration of bones and tissues as well as chronic diseases like diabetes and arthritis. According to the National Library of Medicine, adults over the age of 60 had a much greater incidence of rotator cuff tendon rupture, long head of the biceps tendon lesions, and rotator illnesses. Moreover, rising cases of tendon injuries during sports and other athletic activities are expected to augment segment growth. Around 30% of runners, 14% of volleyball players, and 12% of basketball players experience a tendon injury each year.

Our in-depth analysis of the global soft tissue allografts market includes the following segments:

                   By Type

  • Cartilage Allograft
  • Tendon Allograft
  • Meniscus Allograft
  • Dental Allograft
  • Collagen Allograft
  • Amniotic Allograft

                    By Application

  • Orthopedic
  • Dentistry
  • Wound Care
  • Others

                   By End-User

  • Hospitals
  • Orthopedic Clinics
  • Aesthetic Centers
  • Dental Clinics
  • Others

Global Soft Tissue Allografts Market Regional Synopsis


The North American soft tissue allografts market, amongst the market in all the other regions, is projected to hold the largest market share by the end of 2035. The growth of the market can be attributed majorly to the rising prevalence of arthritis, and rising healthcare expenditure on its treatment. In the United States, around 59 million adults, or approximately 24% of the population, suffer from arthritis.  Osteoarthritis is the most prevalent type of arthritis. Gout and lupus are further kinds. Moreover, the annual cost of medical care for arthritis is around USD 300 billion. In addition to this, the surging need for rheumatoid arthritis treatment is another substantial factor that is estimated to boost the market growth further in the region over the projected time frame.


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Top Featured Companies Dominating the Global Soft Tissue Allografts Market

    • Stryker Corporation
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • CONMED Corporation
    • LifeSciences Corporation
    • Organogenesis Inc.
    • RTI Surgical, Inc.
    • MIMEDX, Inc.
    • Xtant Medical Holdings, Inc.
    • Globus Medical, Inc.
    • Bone Bank Allografts


In The News

  •  AlloSource, one of the leading providers of allograft in the United States, announced the launch of AlloMend Extra Large (XL) Acellular Dermal Matrix (ADM). It is so far the biggest dermal graft launched by the company. It is available in mesh and non-mesh variations for use in demanding soft tissue applications.

  • RTI Surgical, Inc. and Zimmer Biomet partnered with the American Academy of Implant Dentistry Foundation (AAIDF) to provide dental implants and wound care products for an initiative supporting veterans of the United States Armed Forces.



Global Economic Impact

Request Insights
Despite Inflation & Fearing Recession, Businesses Across the Globe Expected to Do Better in 2023:

In 2023, market players might incur losses due to huge gap in currency translation followed by contracting revenues, shrinking profit margins & cost pressure on logistics and supply chain.
Controlling Inflation has become the first priority for global economies from last quarter of 2022 and to be followed in 2023. With skewed economic situations, rise in interest rate by governments to control spending and inflation, spiked oil and gas prices, high inflation, geo-political issues including U.S. & China trade war, Russia-Ukraine conflict to intensify the global economic issues.
The interest rates in the U.S. may be less sensitive in 2023 as compared to 2022; sigh of relief for businesses. Positive business sentiments, healthy business balance sheets, growth in construction spending (private construction value in 2022 stood at $1,429.2 billion, 11.7 percent (±1.0 percent) above the $1,279.5 billion spent in 2021, Residential construction in 2022 was $899.1 billion, up by 13.3 percent (±2.1 percent) from $793.7 billion in 2021, non-residential construction touched $530.1 billion, 9.1 percent (±1.0 percent) above the $485.8 billion in 2021.) showcases minimal impact of recession in the country.
Similarly, spiked spending in the European and major Asia economics including, India, China & Japan to showcase less impact on the global demand.

Author Credits:  Radhika Gupta, Shivam Bhutani

Key Questions Answered in the Report

1) What are the major factors driving the growth of the soft tissue allografts market?

Ans: Growing incidences of sports injuries, rising prevalence of osteoarthritis, increase in trauma cases, and upsurge in musculoskeletal diseases are the major factors driving the market growth.

2) What would be the CAGR of soft tissue allografts market over the forecast period?

Ans: The market is anticipated to attain a CAGR of ~7% over the forecast period, i.e., 2023 – 2035.

3) What are the challenges affecting the soft tissue allografts market growth?

Ans: High cost of treatment, unfavorable compensation policies, and lack of skilled personnel are estimated to be the growth hindering factors for the market expansion.

4) Which region will provide more business opportunities for growth of soft tissue allografts market in future?

Ans: The market in the North American region is projected to hold the largest market share by the end of 2035 and provide more business opportunities in the future.

5) Who are the major players dominating the soft tissue allografts market?

Ans: The major players in the market are Stryker Corporation, ALON SOURCE GROUP, CONMED Corporation, Integra LifeSciences Corporation, Organogenesis Inc., RTI Surgical, Inc., MIMEDX, Inc., and Xtant Medical Holdings, Inc.

6) How are the company profiles selected?

Ans: The company profiles are selected based on the revenues generated from the product segment, the geographical presence of the company which determines the revenue generating capacity as well as the new products being launched into the market by the company.

7) What are the segments in the soft tissue allografts market?

Ans: The market is segmented by type, application, end user, and by region.

8) Which segment captures the largest market size in application segment in the soft tissue allografts market?

Ans: The dentistry segment is anticipated to garner the largest market size by the end of 2035 and display significant growth opportunities.

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