Sickle Cell Disease Drugs Market Analysis

  • Report ID: 3094
  • Published Date: Jun 16, 2025
  • Report Format: PDF, PPT

Sickle Cell Disease Drugs Market Segmentation:

Drug Class Segment Analysis

Gene therapy is the dominant segment that is expected to hold a market share of 38.5% by 2037. The approval received from the Food and Drug Administration and European Medical Agency for Casgevy and Lyfgenia led to high adoption in the market. The Efficacy of the drug with one-time dosing ensured a better outcome for the sickle cell disease treatment. According to the National Institute of Health, it is projected that the high price point of the gene therapy drug will elevate the revenue accumulation rate in the global market.

Mechanism Action Segment Analysis

The haemoglobin polymerization inhibitors segment is expected to hold a considerable market share by 2037. According to the report of the World Health Organization, hydroxyurea adoption is expanding at a faster scale in the emerging market. Production cost of hydroxyurea is comparatively low in India and Africa as comparison to the US and EU markets. Approximately USD 48 /year is the manufacturing cost of hydroxyurea in India, which is USD 990/year in the U.S. This led to the quick adoption of hydroxyurea and promoted the growth of haemoglobin polymerization inhibitors.

Our in-depth analysis of the global sickle cell disease drugs market includes the following segments:  

Segment 

       Subsegment 

Drug Class

  • Gene Therapy
  • Disease-Modifying Agents
  • Hydroxyurea
  • Crizanlizumab
  • Pain Management
  • NSAIDs
  • Opioids

Mechanism of Action

  • Hemoglobin Polymerization Inhibitors
  • Anti-Adhesion Therapies
  • Fetal Hemoglobin Inducers

Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2025, the industry size of sickle cell disease drugs is estimated at USD 3.1 billion.

Sickle Cell Disease Drugs Market size was over USD 2.9 billion in 2024 and is anticipated to cross USD 7.8 billion by 2037, witnessing more than 12.7% CAGR during the forecast period i.e., between 2025-2037.

North America industry is set to account for largest revenue share by 2037, on the back of advanced medical facilities, and research and development activities.

The major players in the market are Pfizer Inc. (U.S.), Novartis AG (Switzerland), Bluebird Bio (U.S.), Vertex Pharmaceuticals (U.S.), Sanofi (France) and others.
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