Plasmid DNA Manufacturing Market Market Analysis

  • Report ID: 6369
  • Published Date: Sep 18, 2025
  • Report Format: PDF, PPT

Plasmid DNA Manufacturing Market Segmentation:

By Product Segment Analysis

The viral vector segment in the plasmid DNA manufacturing market will emerge as the dominant segment with a revenue share of 21.1% by 2035, owing to the growing demand for gene therapies and vaccines. Viral vectors are utilized as a tool which is involved in delivering genetic materials into the cell, and their usage has revolutionized the field of gene therapy and vaccine development.

There are also advancements in vector designing and manufacturing that have contributed to the growth of the plasmid DNA market by making it more efficient, reliable, and effective. Persistent innovation and discoveries have been spurred, collaborations between industry and academia, and government assistance in funding initiatives have fueled the propelled exploration.

In April 2024, Charles River Laboratories announced a collaboration with Axovia Therapeutics to produce high-quality gene of interest plasmids and extend its assistance in the development of procedure of gene therapies for ciliopathies, including Bardet-Biedl Syndrome (BBS).

By Development Phase Segment Analysis

Clinical therapeutics segment will account for 55% of the plasmid DNA manufacturing market share by 2035. As the demand for gene therapy and vaccines continues to soar, this sector of market has capitalized on the trend, solidifying its position. With its strong pipeline of products and cutting-edge technologies, the clinical therapeutics sector is poised to drive growth and shape the future of plasmid DNA manufacturing market. For example, In December 2021, Plasmid DNA-based cancer immunotherapies, such as VGX-3100, have shown promising results in clinical trials.

By Disease Segment Analysis

The oncology segment in the plasmid DNA manufacturing market is expected to account for the largest revenue share during the forecast period. This segment is expanding as a result of the increased use of DNA plasmids in cancer treatments. Numerous gene therapy approaches, inclusive of oncolytic virotherapy, immune modulation based on gene therapy, and genetic modification of apoptotic cells, are used to treat cancer. Thus, there's a greater need for plasmid DNA, the driving force behind segment growth. Rare genetic disorders, such as sickle cell anemia and muscular dystrophy are also being targeted for expected results.

Our in-depth analysis of the plasmid DNA manufacturing market includes the following segments

By Product

  • Viral Vectors
  • Plasmid DNA
  • Lipid/Polymers
  • Nanoparticles
  • Others

By Application

 

  • Cell and Gene therapy
  • Immunotherapy
  • DNA Vaccines
  •  Others

By Disease

  • Cancer
  • Infectious Diseases
  • Genetic disorders
  • Other

By Developmental Phase

  • Pre-Clinical Therapeutics
  • Clinical Therapeutics
  • Marketed Therapeutics

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2026, the industry size of plasmid DNA manufacturing is evaluated at USD 2.91 billion.

The global plasmid DNA manufacturing market size exceeded USD 2.48 billion in 2025 and is set to register a CAGR of over 19.4%, exceeding USD 14.6 billion revenue by 2035.

The North America plasmid DNA manufacturing market will account for 42% share by 2035, driven by strong R&D infrastructure, government funding, and innovation in biotechnology.

Key players in the market include JAFRAL, Ltd., Delphi Genetics, Aldevron, VGXI, Inc., and Akron Biotech are some prominent companies in the plasmid DNA manufacturing market.
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