Oncolytic Virus Therapy Market Analysis

  • Report ID: 2988
  • Published Date: Sep 08, 2025
  • Report Format: PDF, PPT

Oncolytic Virotherapy Market Segmentation:

End User Segment Analysis 

The hospitals segment is estimated to account for the largest share of 67% in the oncolytic virotherapy market over the discussed timeframe. Hospitals will continue to dominate the end-use segment due to their capacity to administer biologics, their oncology specialty and expertise, their allocation of resources to clinical research, and their ability to provide a complete patient access pathway. Hospital-based oncology centers often access more complex therapies sooner than hospital-affiliated community oncologists, as well as have a more elaborate trial process for new oncolytic agents. These advantages of hospitals will lead to increased patient access to oncolytic viruses for their comprehensive treatment approaches.

Type Segment Analysis  

The genetically engineered viruses segment is poised to dominate the market. Genetically engineered viruses are at the forefront of development because they can be designed to target tumors more precisely than other options. Moreover, they potentially could make the treatment safer by transferring genes to reduce off-target effects, and they can improve immune activation. Clinical developments such as talimogene laherparepvec (T-VEC) also illustrate the relevance of genetic modifications, and indicate that the modifications could make treatment safer and more effective in human trials

Application Segment Analysis  

The solid tumors segment is likely to grasp a substantial share of the market. Solid tumors are by far the largest application segment, based on the high global incidence of breast, lung, and prostate cancers. Oncolytic viruses can infiltrate tumor microenvironments and replicate instead of favorably, where conventional treatments may fail. With advanced solid tumours on the rise, the need for alternative locoregional treatments is warranted.

Our in-depth analysis of the oncolytic virotherapy market includes the following segments: 

Segments

Subsegments

Virus Type

  • Genetically Engineered Oncolytic Viruses
  • Oncolytic Wild‑Type Viruses

Application

  • Solid Tumors
  • Melanoma

Route of Administration

  • Intravenous
  • Intratumoral

End User

  • Hospitals
  • Cancer Research Institutes
  • Specialty Clinics / Ambulatory Centers

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In 2025, the industry size of oncolytic virotherapy is estimated at USD 20.36 billion.

The global Oncolytic Virotherapy Market size was valued at USD 20.36 billion in 2025 and is projected to reach USD 111.76 billion by the end of 2035, rising at a CAGR of 18.89% during the forecast period, from, 2026-2035. In 2026, the industry size of oncolytic virotherapy is assessed at USD 25.03 billion.

Key players in the market are Amgen Inc., Replimune Group Inc., Oncolytics Biotech Inc., Sorrento Therapeutics Inc., PsiOxus Therapeutics Ltd., Transgene S.A., SillaJen Inc., Genelux Corporation, Viralytics Ltd., Shanghai Sunway Biotech Co. Ltd, and other.

The hospitals segment is estimated to account for the largest share of 67% in the oncolytic virotherapy market over the discussed timeframe.

North America is expected to capture the highest share of 34% in the global oncolytic virotherapy market by the end of 2035.
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