Nucleic Acid Labeling Market Size & Share, by Product Type (Reagents, Kits); Labeling Technique (PCR, Nick Translation, Random Primer, In Vitro Transcription, Reverse Transcription, End Labeling); Application (DNA sequencing, PCR, FISH,Microarray, In Situ Hybridization, Blotting); End-user (Diagnostic & Research Centers, Hospitals) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2023-2033

  • Report ID: 4299
  • Published Date: Feb 24, 2023
  • Report Format: PDF, PPT

 Global Nucleic Acid Labeling Market Definition

Molecular structures such as nucleic acids are responsible for transmitting genetic information. A nucleic acid is composed of deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The labeling of nucleic acids can be achieved with enzymes, biotins, and fluorescent tags. Labeling of nucleic acids is used for PCR, fluorescence in situ hybridization (FISH), microarrays, blotting, in situ hybridization, as well as DNA sequencing.

Labeling nucleic acids helps to detect and determine the purity of the genetic material. Furthermore, nucleic acids are of two types DNA or RNA. These are used for the study of therapeutic applications and research to develop new medicines, drugs, or products that are useful to improve healthcare. A radiolabel is literally attached to the nucleic acid in the labeling method to keep track of the modified and unmodified sequence of strands during the test.

Genetically modified nucleic acids are useful to correct the repeated or damaged sequence of genetic material in the therapeutic treatment of genetic disorders. Nucleic acid labeling is used to detect tumors or diseases in the diagnostic sector. The nucleic acid labels are very expensive based on the purification and modification services provided. Also, the sample size should be much larger for modified oligonucleotides, so many researchers prefer to use kits during the generation of probes. 

Global Nucleic Acid Labeling Market: Key Insights

Base Year


Forecast Year




Base Year Market Size (2022)

~ USD 1 Billion

Forecast Year Market Size (2033)

~ USD 4 Billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

Global Nucleic Acid Labeling Market Size, Forecast, and Trend Highlights Over 2023 - 2033

The global nucleic acid labeling market is estimated to garner a revenue of USD 4 Billion by the end of 2033 by growing at a CAGR of ~9% over the forecast period, i.e., 2023 – 2033. Further, the market generated a revenue of USD 1 Billion in the year 2022. The growth of the market can be attributed to the increasing use of polymerase chain reaction (PCR) tests and DNA sequencing across hospitals and laboratory centers owing to the outbreak of various infectious diseases such as the COVID-19 pandemic. For instance, in February 2021, more than 1 million PCR tests were performed in the United States as a consequence of the COVID-19 pandemic. The PCR test is used to determine the genetics of an organism to find out whether it is a virus, bacteria, or any other organism. It is used to find the type of disease or infection a patient is suffering from, so that appropriate treatment is indicated to the patient. The prevalence of infectious diseases across the world that are both contagious and asymptomatic is estimated to drive market growth.


Moreover, the development of healthcare facilities, increasing awareness of early disease diagnosis, along with increasing per capita income are anticipated to propel the demand for nucleic acid labeling during the forecast period. The World Bank reported a 4.8% increase in worldwide income per capita in 2021, compared with 1.5% in 2019. People are becoming more aware of their health with the adoption of early diagnosis tests. The spread of COVID-19 made people more conscious of getting tested if they saw any symptoms that were not common. The government is also paying much attention to the healthcare sector, as it is crucial for a healthy community. Also, the spread of genetic disorders is something that cannot be changed after their incidence. Therefore, it is better to prevent the cause through genetic material testing. Thus, the growth of the market is expected to grow during the forecast period.

Global Nucleic Acid Labeling Market: Growth Drivers and Challenges

Growth Drivers

  • Increase in the Number of Laboratory Experiments and Research Institutes - Data from the World Bank shows that as of 2018, there were 1597 researchers engaged in research and development activities per 1,000,000 people, a significant increase from 1412 researchers per million in 2015 across the globe.  Government organizations are increasing funding for research activities and drug discovery purposes, which is resulting in the development of advanced and innovative treatments for disease diagnosis. There are few companies that offer specific reagents and kits for nucleic acid labeling specifically for research applications, which in turn is expected to enlarge the global nucleic acid labeling market size during the forecast period. 

  • Growing Cases of Infectious Diseases Worldwide Among People - It was observed that in China, the reportable infectious disease cases accounted for more than 6,300,170 in 2020. 

  • Rapid Growth of the Life Science Industry Including Cell and Gene Therapy - According to estimates, nearly USD 10 billion in investment was made in CGT (cell and gene therapy) in 2020 and the investment is expected to grow to USD ~45 billion by the end of 2027 across the globe.

  • Increasing Health Care Expenditures Worldwide to Improve Health Facilities - According to the World Bank, global healthcare expenditures totaled USD 9.83 billion in 2019, an increase of USD 9.7 billion from 2018.

  • Rise in Genomic Research and Development Initiatives - For instance, by increasing the diversity of people participating in genomics research, the National Human Genome Research Institute (NHGRI) is engaged in improving understanding of human genomic variation and genomic information in general.


  • Inadequacies in the Professional and Medical Expertise - There is always advancement in any sector to improve the services provided to the people. Sometimes, it becomes difficult for people to get adopted to new equipment or technology. It is necessary to learn everything about the change to use it efficiently.  Moreover, lack of experienced or skilled professionals is estimated to hinder the growth of the market, as per the market analysis.
  • High Treatment Procedure Costs 
  • Complications Associated with the Techniques

Market Segmentation

The global nucleic acid labeling market is segmented and analyzed for demand and supply by product type into reagents, and kits. Among these segments, the kits segment is anticipated to capture the largest market size in the global nucleic acid labeling market. The growing application of DNA labeling and detection products for detection and purification is expected to drive segment growth during the forecast period. Moreover, the surge in cases of COVID-19 along with the development of advanced labeling kits by key manufacturers for COVID- 19 diagnostics, is further anticipated to fuel segment growth. For instance, Perkin Elmer Inc's new COVID-19 nucleic acid detection kit is an in vitro real-time RT-PCR diagnostic kit for detecting nucleic acid from SARS-CoV-2 in humans with 48 tests included in the kit. The kits help to avoid long waiting times in lines at hospitals and the risk of infections is more in health facilities. The home-tested kits also help to prevent traveling chargers. Even health professionals will save time as everything is assembled in the kit which is disposable after use.

The global nucleic acid labeling market is also segmented and analyzed for demand and supply by application into DNA sequencing, PCR, FISH, microarray, In situ hybridization, botting, and others. The In-situ hybridization segment is estimated to garner the largest share. The rising prevalence of genetic disorders and increasing use of In-situ hybridization in the manufacturing of cancer and genetic disorder drugs or medicines. The increasing growth of infections among people as well as research and development funds to improve the market segment growth is estimated to drive the growth of the market. It is also used to understand the disease such as the DNA or chromosomal abnormalities that cause the disorder. Rising pharmaceutical, diagnostic, and biopharmaceutical companies boost the growth of the segment. As per the estimations of the World Health Organization, about 10 in 1000 people are affected by the monogenic disease across the world.

Our in-depth analysis of the global nucleic acid labeling market includes the following segments:

          By Product Type

  • Reagents
  • Kits

          By Labeling Technique

  • PCR
  • Nick Translation
  • Random Primer
  • In Vitro Transcription
  • Reverse Transcription
  • End Labeling

          By Application

  • DNA sequencing
  • PCR
  • FISH
  • Microarray
  • In Situ Hybridization
  • Blotting
  • Others

         By End User

  • Diagnostic & Research Centers
  • Hospitals

Global Nucleic Acid Labeling Market Regional Synopsis

The North American nucleic acid labeling market, amongst the market in all the other regions, is projected to hold the largest market share by the end of 2033. The growth of the market can be attributed majorly to the growing genomics research, attractive reimbursement policies, and convenient access to new diagnostic solutions owing to the presence of key emerging companies in the region. Furthermore, the increasing spending on healthcare and Medicare along with increased R&D expenditures are expected to drive the nucleic acid labeling market growth in the region during the forecast period. According to the Centers for Medicare & Medicaid Services, a total of USD 4.1 trillion was spent on health care in the United States in 2020, representing an increase of 9.7 percent. Also, in 2020, Medicare expenditures increased by 3.5% to USD 829.5 billion. The study of the genetic material of an organism is helpful in determining the protein structure and building mechanism. Therefore, it is an active ingredient or drug is developed to prevent its growth in or on the human body. DNA is the key to many medicinal discoveries that help to treat diseases that are chronic and harmful.


Top Featured Companies Dominating the Global Nucleic Acid Labeling Market

  • Thermo Fisher Scientific Inc.
    • Company Overview
    • Business Strategy
    • Key Product Offerings
    • Financial Performance
    • Key Performance Indicators
    • Risk Analysis
    • Recent Development
    • Regional Presence
    • SWOT Analysis
  • New England Biolabs
  • PerkinElmer Inc.
  • F. Hoffmann La-Roche AG
  • Merck KGaA
  • Enzo Biochem Inc.
  • Promega Corporation
  • Vector Laboratories
  • Agilent Technologies, Inc.,
  • LubioScience GmbH 



In the News

  • ThermoFisher Scientific Inc., announced the launch of the Thermo Scientific SpeciMAX Stabilized Saliva Collection Kit. To ensure sample safety, this kit inactivates common respiratory viruses to preserve viral nucleic acids. 

  • New England Biolabs (NEB) released Monarch Genomic DNA Purification Kit, by expanding its Monarch Nucleic Acid Purification portfolio. This kit provides extremely high yields of DNA fragment purification and prevents contamination of RNA.

Author Credits:  Radhika Gupta, Shivam Bhutani

  • Report ID: 4299
  • Published Date: Feb 24, 2023
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

Rising healthcare expenditure, R&D activities, along with expansion of life science industry are the major factors driving the growth of the nucleic acid labeling market.

The market is anticipated to attain a CAGR of ~9% over the forecast period, i.e., 2023 – 2033.

High treatment costs along and complications within techniques are estimated to be the growth-hindering factors for the market expansion.

The market in the North America region is projected to hold the largest market share by the end of 2033 and provide more business opportunities in the future.

The major players in the market are Thermo Fisher Scientific Inc., New England Biolabs., PerkinElmer Inc., F. Hoffmann La-Roche AG, GENERAL ELECTRIC COMPANY, Merck KGaA, Enzo Biochem Inc., Promega Corporation, Vector Laboratories, Agilent Technologies, Inc., and LubioScience GmbH.

The company profiles are selected based on the revenues generated from the product segment, geographical presence of the company which determine the revenue generating capacity as well as the new products being launched into the market by the company.

The market is segmented by product type, labeling technique, application, end user, and by region.

The kits segment is anticipated to garner the largest market size by the end of 2033 and display significant growth opportunities.

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