In Situ Hybridization Market Analysis

  • Report ID: 5338
  • Published Date: Sep 11, 2025
  • Report Format: PDF, PPT

In Situ Hybridization Market Segmentation:

Technology Segment Analysis

The fluorescent In situ hybridization (FISH) segment in the in situ hybridization market is estimated to gain a robust revenue share of 55% in the coming years owing to the rising incidence of genetic diseases. It is expected that rising cases of stillbirths, and frequent miscarriages are all signs leading to a hereditary condition that is characterized by one or more anomalies in the genome is referred to as a genetic condition. 

Lately, the majority of in situ hybridization procedures employ fluorescent probes which is a laboratory technique used to detect DNA sequences, and is applied to detect genetic abnormalities, and diagnose congenital diseases. For instance, in industrialized nations, genetic illnesses and congenital anomalies account for over 25% of pediatric hospital admissions, affect more than 4% of all live births, and account for roughly 49% of all infant fatalities.

Additionally, the chromogenic In situ hybridization (CISH) segment is anticipated to garner significant market share. Chromogenic in situ hybridization (CISH), is a cytogenetic method for determining gene amplification using a peroxidase-based chromogenic reaction that is growing in popularity as a useful, affordable, and legitimate alternative to fluorescent in situ hybridization when testing for gene alteration, particularly in centers that focus primarily on immunohistochemistry (IHC).

Probe Segment Analysis

The DNA segment in the in situ hybridization market is set to garner a notable share shortly. In situ hybridization uses many different kinds of probes; including a DNA probe that is a popular technique for mapping sequences to certain chromosomal regions, and can be used to hybridize to a sample's known target DNA or mRNA sequence. Besides this, the probes can be utilized to find the location of the mRNA and are used to enzymatically integrate nucleotides with amine modifications.

End-User Segment Analysis

The research & diagnostic laboratories segment in the in situ hybridization market is poised to garner a significant share by the year 2035. In situ, hybridization is a laboratory method for recognizing certain mRNA species within individual cells in tissue sections and is widely being utilized for scientific purposes, including clinical cytogenetics, gene mapping, tumor biology, and investigations of chromosome evolution.

Application Segment Analysis

The cancer segment is anticipated to gain a notable market share during the forecast timeframe. In Situ, the Hybridization test is effective for detecting some forms of the disease and can provide information about the genetic makeup of cancer. Besides this, this method can more accurately predict the prognosis and course of specific cancers, such as leukemias, lymphomas, melanoma, bladder cancer, and others, and can be employed in research to identify other diseases, and lowering the risk of birth deformities through in vitro fertilization (IVF).

Our in-depth analysis of the global in situ hybridization market includes the following segments:

                                        Technology

  • Fluorescent In Situ Hybridization (FISH)
  • Chromogenic In Situ Hybridization (CISH)

                                          Product

  • Instruments
  •  Kits & Probes
  • Software, Services

                                           Probe

  • DNA
  • RNA

                                       Application

  • Cancer
  • Cytogenetics
  •  Developmental Biology
  • Infectious Diseases
  • Neuroscience

                                          End-User

  • Research & Diagnostic Laboratories
  • CROs
  •  Academic Institutes
  • Pharmaceutical & Biotechnological Companies
 

Browse key industry insights with market data tables & charts from the report:

Frequently Asked Questions (FAQ)

In the year 2026, the industry size of in situ hybridization is estimated at USD 1.84 Billion.

The global in situ hybridization market size was more than USD 1.73 Billion in 2025 and is anticipated to grow at a CAGR of over 7.3%, reaching USD 3.5 Billion revenue by 2035.

North America’s in situ hybridization market will dominate more than 45% share by 2035, fueled by rising healthcare spending and adoption of diagnostic technologies.

Key players in the market include Thermo Fisher Scientific Inc., Abbott, PerkinElmer, Inc., Leica Biosystems Nussloch GmbH, F. Hoffman-La Roche Limited, NeoGenomics Laboratories, Inc., Advanced Cell Diagnostics, Inc., BioView, Agilent Technologies, Inc., Merck KGaA, Bio-Rad Laboratories, Inc., Oxford Gene Technology IP Limited.
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