Botulinum Toxin Market Size & Share, by Toxin Type (A, B); Application (Medical, Aesthetic); Gender (Female, Male); Age Group (13-19, 20-29, 30-39, 40-54, 55, Above); End-user (Hospitals, Dermatology Clinics, Spas, Cosmetic Centers) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2023-2033

  • Report ID: 4546
  • Published Date: Feb 27, 2023
  • Report Format: PDF, PPT

Global Botulinum Toxin Market Definition

Botulinum toxin (abbreviated as BTX or BoNT) is created by Clostridium botulinum, a gram-positive anaerobic bacterium. It is a neurotoxin formed by the bacterium Clostridium botulinum and is one of the most toxic biological substances known. It is also known as "miracle poison" and is widely found in soil, plants, water, and in animal intestinal tracts. It is widely utilized in almost all medically specialized fields. Clostridium botulinum produces eight antigenically distinct exotoxins. The most effective toxin is type A, followed by variants B and F. Types A, B, and E are closely attributed to systemic botulism in humans.

BTX is utilized to administer and treat several therapeutic objectives. Chronic migraine, spastic diseases, cervical dystonia, and detrusor hyperactivity are all therapeutic uses. In medical settings, Botulinum toxin is also utilized to treat overactive bladder, urinary incontinence, extreme underarm sweating, eyelid contractions, crossed eyes, and drooling. In addition, it is used in cosmetology to treat wrinkles and lines on the face. 

Botulinum toxin is used as Botox in aesthetic procedures to cure vertical lines between the brows and on the bridge of the nose, squint lines or crow’s feet at the corners of the eyes, forehead horizontal lines, perioral lines and nasolabial folds around the mouth, and thick platysmal bands around the neck, also identified as "turkey neck." Botox cosmetic is a wrinkle muscle relaxer method that is injected. It temporarily paralyzes muscle using botulinum toxin type A, especially OnabotulinumtoxinA. This injection decreases the visibility of facial wrinkles. Botox is genuinely a non-surgical procedure, and it is considered a risk-free and efficient treatment for fine lines and wrinkles around the eyes. As a result, it is now one of the most frequent and widely practiced aesthetic procedures in the world.

Global Botulinum Toxin Market: Key Insights

Base Year


Forecast Year




Base Year Market Size (2022)

~ USD 4 Billion

Forecast Year Market Size (2033)

~ USD 10 Billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

Global Botulinum Toxin Market Size, Forecast, and Trend Highlights Over 2023 - 2033

The global botulinum toxin market is estimated to garner a revenue of ~USD 10 billion by the end of 2033 by growing at a CAGR of ~9% over the forecast period, i.e., 2023 – 2033. Further, the market generated a revenue of ~USD 4 billion in the year 2022. The growth of the market can be attributed to the globally increasing proportion of the geriatric population, which is more prone to deal with numerous health and skin issues. Further, the rising demand for minimally invasive or noninvasive surgeries such as - glabellar lines, and chemical browlift treatments is estimated to propel market growth during the forecast period. As per the estimations, it is found that noninvasive treatments such as dermal fillers and botox rose by over 180% in the United States, and in 2018 more than 70% of U.S surgeons noted the increase in the use of injectables among people under 30 years.Botulinum-Toxin-Market-overviewGet more information on this report:Download Sample PDF

In addition to these, factors that are believed to fuel the market growth of botulinum toxin include the rising ratio of people who are dealing with premature aging issues or photoaging, since the premature aging issue is such a significant factor that has been playing a pivotal role in the surging level of various kinds of cosmetic surgeries. Additionally, soaring investment by the major key players to enhance the research and development, coupled with growing expenditure for developing advanced healthcare infrastructure, and rising amendments in reimbursement policies to cover the botulinum procedures and injections are anticipated to present the potential for market expansion over the projected period. Besides this, a worldwide surge in healthcare expenditure is also estimated to expand the market size of botulinum toxin in the coming years.

Global Botulinum Toxin Market: Growth Drivers and Challenges

Growth Drivers

  • Increasing Disposable Income of Individuals – Botox is an expensive treatment, and not everytreatments are estimated to propel market growth during the forecast period. The disposable income of the U.S. rose from -0.4% in Jun 2022 to 0.1% in Aug 2022 as per the Bureau of Economic Analysis.

  • Growing Prevalence of Neurological Disorders – As per medical terms, neurological diseases are issues that impact the brain as well as the nerves found throughout the human body, including the spinal cord. A variety of symptoms can be triggered by structural, metabolic, or electrical dysfunctions in the brain, spinal cord, or other nerves. The surging prevalence of this condition is expected to boost the growth of the market. As per the observations, more than 18 million Americans suffer from some kind of neuropathy issue, and over 15% of U.S households have at least one person with a brain impairment disorder. Thus, the demand for botulinum toxin has been massively increasing. As botulinum neurotoxin A (BoNT/A) has transformed the treatment of dystonia and focal spasticity by becoming a helpful tool in the treatment of neurological illnesses related to increased muscular tone.

  • Rising Number of Product Approvals and Launch – For instance, it has been estimated that the number of Botox injections rose by about 450% between 2000-2020 across the globe.

  • Increasing Number of Cosmetic Surgeries – It is estimated that in the U.S. in 2020, more than USD 15 billion was spent on aesthetic treatments.

  • Elevating Use of Botulinum Toxin Injection for the Treatment of Glabellar, Chemical Browlift, Perioral, and Periorbital Lines – For instance, nearly 85% of the 15 million cosmetic procedures done are minimally invasive, such as botulinum toxin or soft tissue filler injections.

person is able to afford it. On the other hand, with rising disposable income, people are focusing more on how they look and are willing to spend on facial treatments. Botox costs about USD 10-15 per unit anywhere across the globe, and more than USD 400 for the full treatment. The rising adoption of minimally invasive procedures and the high willingness of people to spend on aesthetically looking


  • Associated Side Effects with the Botulinum Toxin Procedures - Botulinum toxin injections are generally well-tolerated with few side effects. Idiosyncratic reactions are rare, usually mild, and temporary. Moderate injections cause discomfort, and local edema, erythema, temporary numbness, headache, malaise, or mild nausea are possible. Thus, this factor is estimated to dampen the market’s growth during the projected time frame.
  • High Cost of Botulinum Toxin Methods
  • Rise of COVID – 19

Market Segmentation

The global botulinum toxin market is segmented and analyzed for demand and supply by end-user in hospitals, dermatology clinics, spas, and cosmetic centers. Amongst these four segments, the hospitals segment is anticipated to hold the largest market size by the end of 2033. The growth of this segment can be attributed to the increasing number of hospitals with advanced cases and facilities, followed by the rising awareness regarding aesthetic procedures in individuals. For instance, the number of hospitals in the United Kingdom has increased to nearly 29 per one million people in the year 2019. Moreover, a growing number of medical spas and cosmetic centers is another significant factor that is estimated to boost the growth of the market, as the surge in cosmetic centers and spas generate more traction in people to access beauty procedures. For instance, in the U.S. there are about 20,000 health and wellness spas as of 2022.

The global botulinum toxin market is also segmented and analyzed for demand and supply by product type into botulinum toxin A and botulinum toxin B. Out of these, the botulinum toxin A segment is expected to garner a significant share. The significant growth in this segment is backed by the escalating utilization of botulinum toxin A to treat headaches as of hypertension, chronic migraine, and several primary neurological diseases. In addition to these, the penetration of botulinum toxin A products has been growing in the wide range of aesthetic purposes, therefore, the proliferating demand for aesthetic beauty products is also anticipated to fuel the growth of the market during the forecast period.

Our in-depth analysis of the global botulinum toxin market includes the following segments:

       By Product Type

  • Botulinum Toxin A
  • Botulinum Toxin B

       By Application

  • Medical
  • Aesthetic

        By Gender

  • Female
  • Male



     By Age Group

  • 13-19
  • 20-29
  • 30-39
  • 40-54
  • 55 and Above


      By End-User

  • Hospitals
  • Dermatology Clinics
  • Spas
  • Cosmetic Centers

Global Botulinum Toxin Market Regional Synopsis

The North American botulinum toxin market, amongst the market in all the other regions, is projected to hold the largest market share by the end of 2033. The growth of the market can be attributed majorly to the increasing spending capacity of individuals, which has been fueling the urge to be more attractive and to use several aesthetic products to improve their physical beauty. For instance, the consumer spending capacity of U.S. people rose from -0.2% in July 2022 to 0.6% in July Sept 2022, as per the Bureau of Economic Analysis. Further, the rising number of cosmetic procedures to look beautiful, escalating adoption of facial injectables, and the rapid adoption of aesthetic procedures among individuals, are also anticipated to contribute to the market growth in the region. In addition to this, the growing advancements in medical and aesthetic procedures are some more factors that are estimated to propel market’s growth further throughout the forecast period in the region.

Whereas, the Asia Pacific botulinum toxin market is anticipated to witness a larger CAGR over the projected time frame on the back of the presence of a larger patient pool for minimally invasive surgeries, along with, increasing demand for botulinum toxins in the countries such as China, and Japan. Additionally, the highly growing beauty consciousness, coupled with the surge in wellness tourism, is elevating the number of spas, and cosmetic centers in the countries such as Korea, Thailand, Singapore, and so on. These are other significant factors that are projected to propel the growth of the botulinum toxin market during the projected timeframe in the region. For instance, in 2018, the number of wellness spas in the Asia Pacific region reached approximately 93,565. Such an extraordinary boost in the count of wellness spas in this region is indicating a higher increase in the same over the coming years, which is projected to further drive market growth in the region.Botulinum-Toxin-Market-share

Top Featured Companies Dominating the Global Botulinum Toxin Market

  • Merz Pharma GmbH & Co. KGaA
    • Company Overview
    • Business Strategy
    • Key Product Offerings
    • Financial Performance
    • Key Performance Indicators
    • Risk Analysis
    • Recent Development
    • Regional Presence
    • SWOT Analysis
  • Medytox Inc.
  • Hugel, Inc.
  • Ipsen Group
  • Revance Therapeutics, Inc.
  • AbbVie Inc.
  • Galderma S.A.
  • Evolus, Inc.


In the News

  • Allergan, an AbbVie Inc. announced the U.S Food and Drug Administration (FDA) approval to expand the label of botox to include eight more muscles to treat adults with upper limb spasticity. The new approval was significant as it treated disabling neurological conditions influencing the quality of life of a patient.

  • Ipsen Group declared that Dysport, a clostridium botulinum type A toxin-haemagglutinin complex received the U.S. FDA. Dysport is the first UK botulinum toxin to get approved for pediatric spasticity therapy in upper and lower limbs.

Author Credits:  Radhika Gupta, Shivam Bhutani

  • Report ID: 4546
  • Published Date: Feb 27, 2023
  • Report Format: PDF, PPT

Key Questions Answered in the Report

1) What are the major factors driving the growth of the botulinum toxin market?

Ans: Rising disposable income and the growing prevalence of neurological disorders are the major factors driving the growth of the botulinum toxin market.

2) What would be the CAGR of botulinum toxin market over the forecast period?

Ans: The market is anticipated to attain a CAGR of ~9% over the forecast period, i.e., 2023 – 2033.

3) What are the challenges affecting the botulinum toxin market growth?

Ans: Associated side effects with the botulinum toxin procedures, and high cost of botulinum toxin methods are estimated to be the growth hindering factors for the market expansion.

4) Which region will provide more business opportunities for growth of botulinum toxin market in future?

Ans: The market in the North American region is projected to hold the largest market share by the end of 2033 and provide more business opportunities in the future.

5) Who are the major players dominating the botulinum toxin market?

Ans: The major players in the market are Merz Pharma GmbH & Co. KgaA, USWM LLC, Revance Therapeutics, Inc., Ipsen Group, Medytox, Inc., Hugel, Inc., AbbVie Inc., Galderma S.A., Evolus, Inc. and others.

6) How are the company profiles selected?

Ans: The company profiles are selected based on the revenues generated from the product segment, the geographical presence of the company which determines the revenue generating capacity as well as the new products being launched into the market by the company.

7) What are the segments in the botulinum toxin market?

Ans: The market is segmented by product, application, gender, age group, end-user, and by region.

8) Which segment captures the largest market size in by type segment in the botulinum toxin market?

Ans: The hospitals segment is anticipated to garner the largest market size by the end of 2033 and display significant growth opportunities.


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