Antibody Purification Services Market Size & Share, by Type (Physiochemical Fractionation, Class-Specific Affinity, Antigen-Specific Affinity); Antibody Type (Monoclonal, Polyclonal, Recombinant); Source (Rabbit, Chicken, Guinea pig, Goat, Mouse, Rat), Application (Oncology, Infectious diseases, Immunology, Neurobiology, Stem cells,Cardiovascular Disease) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2024-2036

  • Report ID: 5923
  • Published Date: Mar 27, 2024
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2024-2036

Antibody Purification Services Market size is expected to reach a USD 3 Billion by the end of 2036, growing at a CAGR of 12% during the forecast period, i.e., 2024-2036. In the year 2023, the industry size of antibody purification services was USD 1 Billion. The increasing number of cases of chronic diseases across the world will exponentially help the market to grow in the expected CAGR. WHO stated that even though the overall health problem is in a better place now, the rising burden of non-communicable diseases (NCDs) may impact massively on the world. If current trends of chronic diseases continue, by approximately 2050, chronic illnesses like cancer, diabetes, cardiovascular disease, and respiratory disorders will be responsible for 86% i.e. around 90 million deaths annually; this represents a startling 90% increase in absolute numbers since 2019.

Another reason to propel the antibody purification services market by the end of 2036 is the rising use of therapeutics to treat diseases globally. Presently, almost 4,000 uncommon diseases are not cured appropriately, and only 10% of rare diseases worldwide are treated appropriately. In China, where there are more than 1.4 billion people, there is a strong social need for drug research and solutions for rare diseases despite the low prevalence of these conditions. For instance, in modern medicine, gene therapy is at the forefront. These cutting-edge technologies have the potential to create one-time, permanent cures for infectious and non-communicable diseases (including HIV and sickle cell disease), which afflict tens of millions of people worldwide, the majority of whom reside in low- and middle-income countries (LMICs), by precisely altering the human genome. Although the gene therapy field is still in its infancy, significant funding and early clinical achievements have given it a lot of momentum.

Antibody Purification Services Market
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Antibody Purification Services Market: Growth Drivers and Challenges

Growth Drivers

  • Increasing Requirement for Digital Therapeutics - Digital therapeutics (DTx) represent a novel therapeutic approach grounded on digital technology. As such, there is a marked demand for the clinical use and commercialization of DTx, as well as for its expansion into other clinical sectors. Nevertheless, there is still uncertainty around the use of DTx as a general medicinal component. This uncertainty may stem from a lack of agreement on a definition as well as deficiencies in clinical studies, R&D, regulatory framework standardization, and technological maturity. Patients are more empowered than ever because of the shift to digital healthcare. Because of this, digital health solutions are now essential to coping with the growing number of empowered patients who are making their own treatment decisions.
  • Increase in Externalization of Antibody Manufacturing and Purification Services - Numerous firms have several therapeutic monoclonal antibodies (mAbs) in their pipelines, and hundreds are presently under research. This review covers the current approach employed in these compounds' recovery operations. A survey is conducted on fundamental unit activities, including harvest, Protein A affinity chromatography, and extra polishing procedures. There is a discussion of substitute procedures including flocculation, precipitation, and membrane chromatography. The mAb product demand grew quickly, which led to simultaneous measures to boost production capacity by building sizable bulk manufacturing facilities and enhancing cell culture procedures to increase product titers. In addition to improvements in traditional purifying technologies, this combination has resulted in an excess of manufacturing capacity and promises almost infinite production capacity shortly.
  • Growth of Contract Production Companies - In response to the COVID-19 pandemic, the creation of mRNA vaccines and their subsequent global manufacturing marks a significant advancement in the production of antibodies. There are about 220 mRNA candidates under research at the moment, and nucleotide-based treatments and vaccinations should see faster growth. The pandemic has concentrated CDMO efforts on quickly scaling up production for commercial supply, but as a result of this new generation of molecules, there is an increasing need for technology and outsourced early-phase development services.


  • Higher Cost of Antibody Purification Services - Depending on the kind and procedure utilized in the production process, the price of producing an antibody can change. Gene synthesis, recombinant expression, antigens, purification, and protein expression services should all be included in the package's pricing. Most manufacturers and laboratories that specialize in creating custom antibody services estimate that the cost will be approximately USD 899. The typical cost of producing a monoclonal antibody might range from USD 6000 to USD 15000 due to its complexity and increased expense. The process of creating an antibody has been made easier by technological developments, and large-scale antibody production is now feasible. For the most part, biochemical researchers have been quite concerned about custom antibody manufacturing. However, most individuals don't realize how expensive the entire procedure is, so they would rather purchase an antibody that has already been made for use in research, medicine, and vaccine development.
  • Lack of Knowledge in People
  • Lack of Infrastructure in Growing Countries

Antibody Purification Services Market: Key Insights

Base Year


Forecast Year




Base Year Market Size (2023)

~USD 1 Billion

Forecast Year Market Size (2036)

~USD 3 Billion

Regional Scope

  • North America (North America, Canada, Mexico)
  • Europe (Germany, Spain, UK, France, Italy, Russia, Others)
  • Asia Pacific (Japan, China, India, Australia, Others)
  • Middle East and Africa (South Africa, UAE, Others)
  • Latin America (Brazil, Argentina, Others)
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Antibody Purification Services Segmentation

Type (Physiochemical Fractionation, Class-Specific Affinity, Antigen-Specific Affinity)

The antigen-specific affinity segment is expected to hold around 47% share of the global antibody purification services market by 2036.because of the rising demand for antigen-specific affinity in various applications. Based on the interaction between particular immobilized ligands and target antibodies, antigens, and so forth, affinity chromatography is an effective approach for separating antibodies, antigens, and proteins. Antibodies or their Fab fragments can be separated using populations of available ligands. Immunoaffinity chromatography (IAC) on low-affinity immobilized antibodies can also be used to isolate antigens. The natural affinity proteins of bacteria, like pA and pG, were the most often utilized when IgG affinity proteins were first created for use in antibody purification. Macromolecules and antibodies have a molecular weight of about 150 kDa. Antigen-binding fragment (Fab) and crystallizable fragment (Fc) combine to produce an antibody molecule, which has a "Y" shape.

Antibody Type (Monoclonal Antibodies, Polyclonal Antibodies, Recombinant Antibodies)

The monoclonal antibodies segment is expected to hold around 74% share of the global antibody purification services market by 2036 owing to the increasing financing on the research on monoclonal antibodies to create new therapeutics across the world. 2019 saw mAbs for inflammatory and cancerous conditions account for seven of the ten best-selling new medications. The US, Europe, and Canada account for 80% of the global market for mAb sales. 85% of the world's population lives in the rest of the world, while just 20% of mAbs are sold. Products containing monoclonal antibodies have emerged from relative obscurity in the 1990s to a position where they increasingly control patient impact and revenue creation. The past 20 years have seen a significant portion of this accomplishment, and we have pinpointed elements linked to the astounding developments that have aided in the identification, creation, and acceptance of monoclonal antibodies.

Our in-depth analysis of the global antibody purification services market includes the following segments:


  • Physiochemical Fractionation
  • Class-Specific Affinity
  • Antigen-Specific Affinity

          Antibody Type

  • Monoclonal Antibodies
  • Polyclonal Antibodies
  • Recombinant Antibodies

          End-Use Industry

  • Pharmaceutical and Biotechnology Companies
  • Academic and Research Companies
  • Contract Research Organizations

          Service Type

  • Antibody Development
  • Antibody Production
  • Downstream Antibody Services
  • Antibody Purification Services
  • Antibody Fragmentation
  • Conjugation


  • Rabbit
  • Chicken
  • Guinea pig
  • Goat
  • Mouse
  • Rat


  • Oncology
  • Infectious diseases
  • Immunology
  • Neurobiology
  • Stem cells
  • Cardiovascular Disease

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Antibody Purification Services Industry - Regional Synopsis

North American Market Analysis

The antibody purification services market in the North America region will have the biggest growth during the forecast period with a revenue share of around 38%. This growth will be noticed owing to the increasing prevalence of cardiovascular diseases in this region. A study released recently in the Journal of the American College of Cardiology projects a considerable increase in the prevalence of cardiovascular risk factors and disease in the United States by the year 2060. Significant rises in cardiovascular trends underscore the need for fair access to preventive education and therapies now to avoid future disease and may put an increasing strain on the American healthcare system.

European Market Forecast

The antibody purification services market in the Europe region will also encounter huge growth during the forecast period, and hold the second position owing to the advancement in healthcare infrastructure in this region. Furthermore, care will be organized around the person by 2040 as opposed to the organizations that run the current healthcare systems. All stakeholders' businesses and operational models will be impacted by these changes, including newly established non-traditional healthcare companies. Since every European country oversees its healthcare system, the consequence is a patchwork of unique systems that are shaped by the unique political, economic, and cultural contexts of each country. Three main sources provide funding for healthcare: government programs, social health insurance (SHI), and private health insurance (PHI).

Research Nester
Antibody Purification Services Market size
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Companies Dominating the Antibody Purification Services Market

    • Antibody Research Corporation
    • Company Overview
    • Business Planning
    • Main Product Offerings
    • Financial Execution
    • Main Performance Indicators
    • Risk Analysis
    • Recent Development
    • Regional Presence
    • SWOT Analysis
    • Thermo fisher
    • Detai Bio-tech Co.
    • Genscript
    • KMD Bioscience
    • Southern Biotech
    • GE Healthcare
    • Creative Biolabs
    • Abcam
    • Chugai Pharmaceutical Co., Ltd.
    • Medicinal Chemistry Pharmaceutical Co., Ltd.
    • Mitsubishi Chemical Group Corp.


In The News

  • Bayer AG and Thermo Fisher Scientific Inc. declared to growth of next-generation sequencing (NGS) --based partner diagnostic assays (CDx) together. These will assist in recognizing patients who may profit from Bayer’s increasing portfolio of accurate cancer treatments by presenting decentralized genomic testing and quick turnaround time.
  • Thermo Fisher Scientific Inc., the world leader in serving science, declared the launch of a fresh CorEvitas-associated clinical registry in generalized pustular psoriasis (GPP). This registry, which is open to registration, is CorEvitas’ 10th syndicated disease registry and appeals to an unmet need for real-world evidence (RWE) associated with the clinical and patient-reported results of patients with GPP.

Author Credits:  Radhika Gupta, Shivam Bhutani

  • Report ID: 5923
  • Published Date: Mar 27, 2024
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

The increasing number of cases of chronic diseases across the world will majorly drive the market growth of the antibody purification services market.

The market size of the antibody purification services market is expected to get a CAGR of approximately 12% over the forecast period, i.e., 2024-2036.

The major players in the market are Antibody Research Corporation, Thermo Fisher, Detai Bio-tech Co., Genscript, KMD Bioscience, Southern Biotech, GE Healthcare, COVALAB, Creative Biolabs, Abcam, Chugai Pharmaceutical Co., Ltd., Medicinal Chemistry Pharmaceutical Co., Ltd., Mitsubishi Chemical Group Corp.

The monoclonal antibodies segment is anticipated to reap the largest market size with almost 74% by the end of 2036 and demonstrate substantial growth scopes.

The market in the North American region is expected to have the largest market share by the end of 2036 and provide more business opportunities in the future.
Antibody Purification Services Market Report Scope

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