Introduction to Nucleic Acid Isolation and Purification Process
The nucleic acid isolation and purification process is referred to the molecular biology techniques in genetic engineering that includes several processes, such as sequencing, cloning, and polymerase chain reaction processes amongst others. The process of nucleic acid isolation and purification is widely used in various healthcare verticals such as life science research, genetic engineering, molecular diagnostics, and forensics. The process of isolation involves mechanical and chemical disruption of biological cells via enzymatic digestion. The process is broadly accepted in areas of biological science where a large number of nucleic acid samples need to be processed in less time. The benefit of nucleic acid isolation and purification process is that it minimizes nucleic acid loss and degradation of the cell, and further increases laboratory efficiency & effectiveness. The nucleic acid isolation and purification process includes a combination of extraction/precipitation, chromatography, centrifugation, electrophoresis, and affinity separation methods and is widely used in recombinant technology methods for targeted purposes in research. Various sources such as hair, blood, bones, sperm, saliva, nails, and urine can be considered for the isolation and the purification of the nucleic acid.
Market Size and Forecast
The global nucleic acid isolation and purification market is estimated to observe a notable growth over the forecast period owing to the growing developments in genetic engineering techniques, increasing applications of genetic engineering techniques for cell isolation processes and the growing use of nucleic acid-based tests in diagnosis. Additionally, RNA extraction processes, which is also known to form a wide, untapped class of biomolecules, that plays an important role during disease progression, is raising the need for the study of different RNA extraction techniques that are applicable for different biological processes, which is also anticipated to promote towards the growth of the global nucleic acid isolation and purification market. Further, rising applications of these techniques in various fields such as genetic engineering, molecular diagnostics, life science research, and forensics, along with the government funding in R&Ds are anticipated to support the development of the global nucleic acid isolation and purification market. This technique is also widely used in diagnosing sexually transmitted diseases. According to the statistics by the US Department of Health & Human Services, as of 2016, there were approximately 36.7 million people living with HIV/AIDS around the globe. Further, in other statistics by the World Health Organization, more than 1 million sexually transmitted infections are acquired every day worldwide. The statistics also stated that 500 million people were estimated to have genital infection with herpes simplex virus (HSV) and 290 million women with human papillomavirus (HPV) infection.CLICK TO DOWNLOAD SAMPLE REPORT
The global nucleic acid isolation and purification market is anticipated to record a notable CAGR over the forecast period i.e. 2020-2028. The market is segmented by type, product, method and by application, out of which, the kit segment of product is anticipated to hold leading shares in the nucleic acid isolation and market owing to the low cost and easy usage of kits in applications such as gene sequencing, molecular diagnostics, and gene cloning. On the contrary, the column-based isolation and purification segment of method sector accounted for the largest share of the global market on account of more cost-effective, simpler, and faster than organic extraction, and can also be automated. Conversely, the medical segment of the end-user sector accounted for the largest share of the market owing to the increasing research activities and the use of nucleic acid tests in molecular diagnostics.
Growing Concern for the Prevalence of Several Infectious Diseases
Globally, throughout the years, several infectious diseases, such as cancer, several genetic disorders and other neglected tropical diseases have spread rapidly and infected people. As a result, there is an increasing concern for the study of these diseases to reduce the spread, which in turn is raising the need for the isolation of the genetic information, i.e. DNA and RNA, for processing nucleic acid-based diagnostics. Nucleic acid-based isolation techniques is one of the most advanced form of genetic engineering analysis which has significantly helped to advance in the healthcare sector. Further, with advancements in the search for several next-generation sequencing (NGS) technologies and for advanced research in genetic engineering study are some of the factors anticipated to drive the growth of the market.
High Costs Involved in Isolation and Purification Processes
The high prices of the instruments associated with these procedures raises the overall isolation and purification costs are one of the key restraints anticipated for the growth of the market.
Our in-depth analysis of the nucleic acid isolation and purification market includes the following segments:
Based on geographically, the nucleic acid isolation and purification market is segmented into five major regions including North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa region.
North America is holding and anticipated to hold the largest share of the global market owing to the increasing application of nucleic acid isolation in food processing, agriculture, and environmental testing. The presence of food safety regulatory bodies for surveillance of processed food products in the U.S., such as the Food and Drug Administration (FDA) and the Food Safety and Inspection Service (FSIS), stipulates the DNA isolation procedures for each type of food product. On the contrary, the Asia Pacific region is expected to witness an escalating growth rate in the near future owing due to growth in DNA and RNA library preparation for next-generation sequencing in countries such as India and China.
The global nucleic acid isolation and purification market is further classified based on region as follows:
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