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Leucovorin Calcium Market Segmentation by Route of Administration (Oral, Injectable, and Others); by End-User (Hospital, Retail Pharmacies, Specialty Clinics, and Others) – Global Demand Analysis & Opportunity Outlook 2031

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Inflation And Looming Recession to Haunt Businesses:

In 2022 & 2023, market players expected to sail in rough waters; might incur losses due to huge gap in currency translation followed by contracting revenues, shrinking profit margins & cost pressure on logistics and supply chain. Further, U.S. economy is expected to grow merely by 3% in 2022.

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Purchasing power in the couPurchasing power in the country is expected to fell nearly by 2.5%. On the other hand, European countries to see the worst coming in the form of energy crisis especially in upcoming winters!! Right after COVID-19, inflation has started gripping the economies across the globe. Higher than anticipated inflation, especially in western world had raised concerns for national banks and financial institutions to control the economic loss and safeguard the interest of the businesses. Increased interest rates, strong USD inflated oil prices, looming prices for gas and energy resources due to Ukraine-Russia conflict, China economic slowdown (~4% in 2022) disrupting the production and global supply chain and other factors would impact each industry negatively.                                                         Request Insights

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  • January 22, 2022: Exelixis Inc. announced the successful results for Cabozantinib in combination with immunotherapies in patients with advanced colorectal cancer.

  • January 28, 2021: PromoCell GmbH to lead a research on immunotherapies through all human primary cells and blood & stem cells, including MHC class I genes HLA-A, -B, and -C.

Global Leucovorin Calcium Market Highlights over 2022 – 2031

The global leucovorin calcium market is estimated to grow at a robust CAGR over the forecast period, i.e., 2022 – 2031. Leucovorin is also known as folinic acid, which is generally used to treat folate deficiency that results in anemia. With calcium, leucovorin is used to treat colorectal and pancreatic cancer. The growth of the market can be attributed to the growing prevalence of colon-rectal cancer, amongst other cancers. According to the data by the World Health Organization (WHO) over 10 million people died due to cancer in 2020, up from 9.6 million in 2018. Moreover, there were 1.93 million new cases of colorectal cancers in 2020 globally. Additionally, colon and rectum cancer caused 916,000 deaths in 2020 itself. Furthermore, the increasing demand for new drugs and treatment methods to treat cancer is also anticipated to boost the market growth. Moreover, government initiatives to provide efficient healthcare to the people, along with increasing individual disposable income are anticipated to boost the market growth. 

Leucovorin Calcium Market

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The market is segmented by end-user into hospital, retail pharmacies, specialty clinics, and others, out of which, the hospital segment is anticipated to hold a substantial share in the global leucovorin calcium market over the forecast period on account of increasing cancer patient pool in the hospitals, backed by the increasing exposure to carcinogens. Moreover, the growing availability of hospitals is also estimated to boost the market growth. 

Major Macro-Economic Indicators Impacting the Market Growth

Healthcare Expenditure per Capita, (USD), 2015-2018

According to the statistics by the World Health Organization, the global per capita healthcare expenditure amounted to USD 1,064.741 in the year 2017. The worldwide healthcare expenditure per person grew from USD 864.313 in 2008 to USD 1,110.841 in 2018, where the U.S. is the top country that amounted to healthcare expenditure of USD 10, 623.85 per capita in 2018. As of 2018, the domestic general government healthcare spending in the U.S. was USD 5355.79, which grew from USD 3515.82 in 2008. These are some of the factors responsible for market growth over the past few years. Moreover, as per the projections by the Centers for Medicare & Medicaid Services (CMS), the estimated average annual percent change related to National Health Expenditures (NHE) in the U.S. was 5.2% in 2020 as compared to 2019 (4.5%). Furthermore, the National Health Expenditures are projected to reach USD 6,192.5 Billion in 2028, where the per capita expenditure is estimated to touch USD 17,611 in the same year. These are notable indicators that are anticipated to create lucrative business opportunities in upcoming years.

Global Leucovorin Calcium Market Regional Synopsis

On the basis of geographical analysis, the global leucovorin calcium market is segmented into five major regions including North America, Europe, Asia Pacific, Latin America and Middle East & Africa region. The market in Europe region is estimated to witness noteworthy growth over the forecast period on the back of growing prevalence of cancer, along with the efficient healthcare system in the region. The market in the North America region is also estimated to gain notable growth over the forecast period, owing to the presence of major pharmaceutical companies in the region, backed by the high healthcare expenditure in the developed countries. As per the data by the U.S. Centers for Medicare & Medicaid Services, the national healthcare expenditure grew by 9.7% to USD 4.1 trillion in 2020.

Leucovorin Calcium Market Share

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The global leucovorin calcium market is further classified on the basis of region as follows:

  • North America (U.S. & Canada) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook

  • Latin America (Brazil, Mexico, Argentina, Rest of Latin America) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook

  • Europe (U.K., Germany, France, Italy, Spain, Hungary, Belgium, Netherlands & Luxembourg, NORDIC (Finland, Sweden, Norway, Denmark), Ireland, Switzerland, Austria, Poland, Turkey, Russia, Rest of Europe), Poland, Turkey, Russia, Rest of Europe) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook

  • Asia-Pacific (China, India, Japan, South Korea, Singapore, Indonesia, Malaysia, Australia, New Zealand, Rest of Asia-Pacific) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook

  • Middle East and Africa (Israel, GCC (Saudi Arabia, UAE, Bahrain, Kuwait, Qatar, Oman), North Africa, South Africa, Rest of Middle East and Africa) Market size, Y-O-Y growth, Market Players Analysis & Opportunity Outlook

Market Segmentation

Our in-depth analysis of the global leucovorin calcium market includes the following segments:

By Route of Administration

  • Oral
  • Injectable
  • Others

By End-User

  • Hospital
  • Retail Pharmacies
  • Specialty Clinics
  • Others

Growth Drivers

  • Increasing Prevalence of Colon-Rectal Cancer
  • Growing Cancer Awareness amongst People


  • High Cost Associated with Cancer Treatment
  • Side Effects of Cancer Treatment Drugs

Top Featured Companies Dominating the Market

  • Exelixis Inc.
    • Company Overview
    • Business Strategy
    • Key Product Offerings
    • Financial Performance
    • Key Performance Indicators
    • Risk Analysis
    • Recent Development
    • Regional Presence
    • SWOT Analysis 
  • PromoCell GmbH
  • Thermo Fisher Scientific Inc.
  • Boehringer Ingelheim GmbH
  • Bayer AG
  • Abbott Laboratories
  • Merck & Co., Inc.
  • Mylan N.V.
  • Novartis International AG
  • Pfizer Inc.


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