DNA Library Preparation Market Size & Share, by Technique (Single-Molecule Real-Time Method, Ion Semiconductor Sequencing Method, Nanopore Sequencing Method, Sequencing by Synthesis Method), Application (Diagnostics, Drug Discovery, Forensic Testing, Animal Research), End-User (Biopharmaceutical Companies, Academic & Research Institutes, Contract Research Organizations, Clinical Laboratories) - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2024-2036

  • Report ID: 5319
  • Published Date: Oct 17, 2023
  • Report Format: PDF, PPT

Global Market Size, Forecast, and Trend Highlights Over 2024-2036

DNA Library Preparation Market size is anticipated to cross USD 156 billion by the end of 2036, expanding around 14% CAGR during the forecast period i.e., 2024-2036. In the year 2023, the industry size of DNA library preparation was over USD 16 billion. DNA library preparation plays a significant role in reducing the number of genetic disorders.  According to a report published by the World Health Organization (WHO), there are approximately 5,000 to 8,000 rare diseases worldwide, most of which include genetic disorders that affect 400 million citizens. Due to changes in the focus of COVID-19 vaccine development, the transmission of the Coronavirus has led to delays in research and development activities of biopharmaceutical companies in the market preparing letters DNA Institute. In some countries, COVID-19 has led to lockdowns, delaying production in the DNA library preparation kits market.

Additionally, the growth of the DNA library preparation market can also be driven by the increasing incidence of genetic diseases all across the globe. Advances in genetic engineering technology will lead to increased demand for the DNA library preparation industry. In the field of drug discovery and clinical diagnostics, the growing demand for genomics will strengthen the market in the assessment period. Furthermore, rising healthcare expenditure and advancement in healthcare infrastructure all across the globe is estimated to positively influence the market expansion in the review period.

DNA Library Preparation Market Overview
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DNA Library Preparation Sector: Growth Drivers and Challenges

Growth Drivers

  • Growing Complex Necessity from Researcher for Life Sciences Industry - The growing and complex needs of life science researchers are the main factor behind the increase in demand for DNA library preparation kits. Furthermore, the growing demand for customized analyzes will drive the growth of the DNA library preparation kits market. Manufacturers of DNA library preparation kits are mainly focused on producing more innovative products. To increase sales of DNA library preparation kits, manufacturers also emphasize collaboration and cooperation with leading research institutions. This further is driving the expansion of the market in the forecast period.
  • Increasing Prevalence of Infectious Diseases and Chronic Diseases – Growing prevalence of infectious as well as chronic diseases such as heart disease, cancer, diabetes, and others are major healthcare burdens globally. These are expected to raise the demand for DNA library preparation in the upcoming period. NGS is increasingly being used to diagnose and monitor these diseases, as well as to develop new treatments. This is leading to increased demand for DNA library preparation in clinical laboratories and research institutions.
  • Surging Awareness Related to Genomics- Another factor behind the growth of the DNA library preparation market is increasing awareness of genomics among professionals. Genomics are study of the genome, which is the complete set of genetic instructions for an organism. Increasing awareness about genomics leads to education about this among more people which makes them interested in their genetic makeup and its relation with their health and well-being. Significantly, awareness among healthcare professionals helps them to understand the genetics of an individual more closely and precisely.
  • Rising Use of DNA Sequencing – Increasing DNA sequencing techniques to identify the mutation is expected to influence the market growth rapidly and raise the market expansion of DNA library preparation in the predicted time period. Therefore, a rise in DNA sequencing is expected to drive the market growth of DNA library preparation in the forecast timeframe.


  • Lack of Standardization – There is a lack of standardization in DNA library preparation protocols, which can make it difficult to compare results from different laboratories. Additionally, a lack of standardization can lead to errors in library preparation as well which can impact the quality of data. There are a number of factors contributing to the lack of standardization in DNA library preparation. One such factor is the diversity of DNA samples. They vary in size, complexity, and purity. This makes it difficult to develop a single library preparation method that is optimal for all types of DNA samples.
  • Ethical and Privacy Concerns Associated is other Significant Factors  Restricting the Market Growth in the Forecast Period.
  • High Cost of DNA Library Preparation is Expected to Pose Limitations on the Market Expansion in the Future Time Period.

DNA Library Preparation Market: Key Insights

Base Year


Forecast Year

2024 – 2036



Base Year Market Size

~USD 16 billion

Forecast Year Market Size

~USD 156 billion

Regional Scope

  • North America (U.S., and Canada)
  • Latin America (Mexico, Argentina, Rest of Latin America)
  • Asia-Pacific (Japan, China, India, Indonesia, Malaysia, Australia, Rest of Asia-Pacific)
  • Europe (U.K., Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)
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DNA Library Preparation Segmentation

Application (Diagnostics, Drug Discovery, Forensic Testing, Animal Research)

In terms of application, the diagnostic segment is set to account for 40% share of the global DNA library preparation market during the by 2036. The growth of this market can be primarily attributed to the escalating manufacturing of new drugs along with increasing and expanding drug discovery. Besides this, growing cases of cancer globally and the increasing focus of key market players towards innovating new medications to deal with the deadly disease of cancer a better way is also significant factor driving the growth of this market in the upcoming future. Cancer is a significant reason behind death nowadays, leading to around 10 million death in the year 2020, reported as by the World Health Organization.   To accurately identify the cause or effect of a disease condition, NGS reliably sequences every gene related to a particular phenotype. Additionally, NGS performs concurrent analysis of several genes, which may save time, money, and tissue if numerous potential disease markers need to be examined.

End-User (Biopharmaceutical Companies, Academic & Research Institutes, Contract Research Organizations, Clinical Laboratories)

Academic & research Institutes segment in end-user are estimated to dominate the market revenue in the forecast period. A surge in the number of collaborations and partnerships among the academic and research institutes along with increasing investment towards the development of genomics and advancement in economic NGS products and facilities for research are anticipated to raise the demand for DNA library preparation market in the projected period.   For example, scientists at the University of California entered into a partnership with Miroculus, Inc., and Purigen Biosystems in March 2021 to develop a ground-breaking tool for personal lab automation for the improvement of an automated PCR-free genome sequencing library preparation the process with micro-input human samples.

Our in-depth analysis of the global market includes the following segments:




  • Single-molecule Real-Time Method
  • Ion Semiconductor Sequencing Method
  • Nanopore Sequencing method
  • Sequencing by Synthesis Method



  • Diagnostics
  • Drug Discovery
  •  Forensic testing
  • Animal Research




  • Biopharmaceutical Companies
  • Academic & Research Institutes
  • Contract Research Organizations
  • Clinical Laboratories

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DNA Library Preparation Industry - Regional Synopsis

North America Market Forecasts

The DNA library preparation market in the North America is estimated to hold the highest CAGR of 32% by the end of 2036. The growth of this market can be attributed to the increasing presence of market players in the region along with growing investment in the drug development industry. The region's market expansion is mostly linked to in-depth disease-based research investigations that have been funded by pharmaceutical oligopolies and academic research centers. For instance, in March 2021, Swift Biosciences and SPT Labtech agreed to work together to improve the company's library preparation kits for use with the mosquito genomics and dragonfly discovery platforms. This will enable Swift Biosciences to offer more library preparation options for degraded DNA, low input RNA, and customized amplicon panels.

Asia Pacific Market Statistics

The Asia Pacific DNA library preparation market is estimated to hold a significant revenue share during the forecast period. The market's expansion can be attributed to an increase in pharmaceutical research and development, a sizable patient base, uniform data, lower costs, and a skilled workforce. In the next years, China is projected to be the preparation of NGS library that generates profits. The expansion of this nation in APAC is predicated on a rise in the NGS market, which is driven by rising life science funds, rising CRO, and an expanding global pharmaceutical market.

Research Nester
DNA Library Preparation Market Region
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Companies Dominating the DNA Library Preparation Landscape

    • Thermo Fisher Scientific Inc.
      • Company Overview
      • Business Strategy
      • Key Product Offerings
      • Financial Performance
      • Key Performance Indicators
      • Risk Analysis
      • Recent Development
      • Regional Presence
      • SWOT Analysis
    • Agilent Technologies
    • PerkinElmer, Inc.
    • Swift Biosciences Inc.
    • Merck KGaA
    • New England Biolabs, Inc.
    • Hamilton Company
    • Eppendorf AG
    • Beckman Coulter Inc.
    • Promega Corporation

In the News

  • Agilent Technologies unveiled a new framework for next-generation sequencing (NGS) library preparation in February 2019 with the aim of efficiently running challenging DNA sequencing assays. The completely automated Magnis NGS preparation system has reagents and protocols that enable quick analyses of several genetic and structural abnormalities, even in samples with deteriorated quality like formalin-fixed paraffin-embedded (FFPE). The company has increased product exposure and attracted more market attention thanks to the announcement.
  •  To develop a quick NGS-based diagnostics technique for the detection of COVID-19, Beckman Coulter Inc., Fry Laboratories LLC, and BioID Genomics Inc. entered into a collaboration agreement in August 2020.

Author Credits:  Radhika Gupta, Shivam Bhutani

  • Report ID: 5319
  • Published Date: Oct 17, 2023
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

The growing prevalence of cancer & infectious diseases and growing drug development are some of the major factors anticipated to drive the growth of the DNA library preparation market.

The market is anticipated to attain a CAGR of ~14% over the forecast period, i.e., 2024-2036.

The major players in the market are of Swift Biosciences Inc., Merck KGaA, New England Biolabs, Inc., Hamilton Company, Eppendorf AG, Beckman Coulter Inc., Promega Corporation., and others.

The diagnostic segment is anticipated to garner the largest market size by the end of 2036 and display significant growth opportunities.

The market in North America is projected to hold the largest market share by the end of 2036 and provide more business opportunities in the future.
DNA Library Preparation Market Report Scope

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