Deferasirox Market Size & Share, by Type (Branded, Generics); Application; Distribution Channel - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2025-2034

  • Report ID: 7875
  • Published Date: Jul 08, 2025
  • Report Format: PDF, PPT

Deferasirox Market Outlook:

Deferasirox Market size was valued at USD 1.8 billion in 2024 and is projected to reach USD 2.7 billion by the end of 2034, rising at a CAGR of 6.1% during the forecast period, i.e., 2025-2034. In 2025, the industry size of deferasirox is evaluated at USD 1.9 billion.

The heightened demand for iron chelation therapies in thalassemia, sickle cell disease, and myelodysplastic syndromes is the key factor propelling augmentation in the worldwide market. Also, the market serves a substantial patient pool with an estimated 1.4 million individuals necessitating deferasirox therapy. In addition, the World Health Organization reports that approximately 310,000 infants yearly are born with severe thalassemia, thereby requiring long-term iron chelation therapy. Furthermore, the U.S. CDC notes that thalassemia affects around 1,200 individuals, with deferasirox recorded as first-line treatment.

Furthermore, the U.S. International Trade Commission states that the supply chain of APIs is especially situated in India and China, which account for 60% of global production. According to the U.S. Bureau of Labor Statistics, the Producer Price Index for these APIs demonstrated a 4.3% year-over-year rise from 2023 to 2024, owing to the rising raw material costs, whereas the Consumer Price Index grew by 3.9% on yearly basis, owing to the payer pricing pressures. Responding to this, the prominent organizations are implementing balanced models, thus denoting a standard market development.

Deferasirox Market Size
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Growth Drivers

  • Proven efficacy and affordability: The presence of authorized clinical validations helped the market to promote its complete potential. Exemplifying this, a study was conducted by AHRQ in 2022, which found that early intervention with this element successfully reduced hospitalizations by 27.5% thereby saving USD 1.3 billion in the U.S. healthcare expenditure in a span of two years. In addition, the NICI guidelines by the U.K. highly recommend deferasirox as cost-effective and first-line therapy, which reduces transfusion-related complications by 35.7%.
     
  • Rigorous strategies and innovations: The strategic implementations and innovations are accelerating upliftment in the market.  For instance, in 2024, Novartis announced a partnership with the U.S.-based hematology clinics that increased its Jadenu market share by a remarkable 18.3%. Besides, Cipla expanded into Latin America, which successfully reduced prices by 25.6% in Mexico, reflecting a stronger potential and wider market scope.

Historical Patient Growth (2010-2020) and Its Impact on Future Market Expansion

Historical Patient Growth Data (2010 - 2020)

Country

2010 (Thousands)

2015

(Thousands)

2020

(Thousands)

CAGR (2010–2020)

U.S.

12.8

18.3

24.8

7.1%

Germany

4.9

6.2

8.1

5.2%

France

3.3

4.2

5.4

5.3%

Spain

2.2

2.9

3.7

5.6%

Australia

1.6

2.2

2.9

6.2%

Japan

6.6

7.9

9.3

3.8%

India

8.9

15.4

28.7

12.7%

China

11.3

19.9

35.1

12.2%

Manufacturer Strategies Shaping the Deferasirox Market

Revenue Opportunities for Manufacturers

Strategy

Company Example

Revenue Impact (2023)

Orphan Drug Designation

Novartis (Jadenu)

+$482 million

Emerging Market Expansion

Cipla (India/Africa)

+$223 million

Medicare Partnerships

Dr. Reddy’s

+$122 million

Pediatric Trials

Sun Pharma (Phase III)

Potential $212 million by 2026

Challenges

  • Mandatory price caps and inadequate reimbursement: The aspect of administrative price controls and lack of optimum financial backup hampers adoption in the deferasirox market. Testifying, this WHO report published in 2023 underscored that price ceilings imposed in the EU nations reduced the profit margins by 52%. Whereas only 43% of the Medicaid programs offer coverage to branded therapeutics owing to their exacerbated costs, i.e., USD 3,100 per month. However, to address this, Dr. Reddy’s launched a USD 900 per month generic that gained 26% Medicaid scripts in 2023.

Deferasirox Market Size and Forecast:

Report Attribute Details

Base Year

2024

Forecast Year

2025-2034

CAGR

6.1%

Base Year Market Size (2024)

USD 1.8 billion

Forecast Year Market Size (2034)

USD 2.7 billion

Regional Scope

  • North America (U.S. and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC, North Africa, South Africa, Rest of the Middle East and Africa)

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Deferasirox Market Segmentation:

Type Segment Analysis

The generics segment is anticipated to garner the largest share of 58.4% in the deferasirox market during the assessed timeframe. Cost containment policies and the API self-sufficiency are the key factors reinforcing the segment’s dominance over this sector. According to the study by WHO, API self-sufficiency in India reduced production costs by 42% with USD 220 to USD 1000 per year pricing, whereas it is USD 3,000 for branded therapeutics. Besides, Cipla in 2023 launched a Deferasirox-DFX, which is priced at USD 900 per year, and it gained 32% additional market share in India owing to the government tenders and physician outreach programs.

Application Segment Analysis

The transfusional iron overload segment is projected to grow at a considerable rate, with a share of 45.5% in the deferasirox market by the end of 2034. The growing disease prevalence and clinical advantages make this subtype preferable among service providers to capitalize on this sector. Exemplifying this, the CDC’s thalassemia report notes that 1.3 million individuals across the world require lifelong chelation. On the other hand, the report from the U.S. FDA stated that Jadenu, once a daily formulation, is improving compliance by 54.3% thus denoting a wider segment scope.

Our in-depth analysis of the deferasirox market includes the following segments:

Segment

Subsegment

Type

  • Branded
  • Generics

Application

  • Transfusional Iron Overload (TDT)
  • Non-Transfusion Dependent Thalassemia (NTDT)
  • Myelodysplastic Syndromes (MDS)
  • Other Rare Disorders

Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies
Vishnu Nair
Vishnu Nair
Head - Global Business Development

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Deferasirox Market - Regional Analysis

North America Market Insights

North America is projected to dominate the global deferasirox market with an estimated 38.9% share during the assessed timeframe. The leadership of the country is attributed to its well-established healthcare infrastructure, higher adoption of therapeutic measures, and robust insurance coverage. On the other hand, the region also hosts substantial diagnostic capabilities, with 95.6% of transfusion-dependent patients receiving regular iron monitoring, as stated by the CDC 2024 report. Further, the region’s dominance is propelled by significant R&D investments and 46% of global clinical trials for next-generation iron chelators.

The U.S. is augmenting its dominance in North America’s deferasirox market owing to the vast group of afflicted population and expanded reimbursement coverage. The HHS report states that the federal funding for these therapies surpassed USD 5.2 billion in 2023, which is 9.3% of its healthcare budget. From 2022 to 2024, Medicare enhanced its spending by 16.6% which is USD 810.3 million, with coverage offered to 91.3% of branded deferasirox expenses. Also, Medicaid allocated USD 1.3 billion with an expansion of 12.2% eligible patients in 2024, reflecting a strong financial backup for underprivileged patients.

Canada is also propagating in the regional deferasirox market on account of substantial budget allocations towards this sector. Indicating the same, Health Canada stated that the federal healthcare system allocated USD 3.3 billion in 2023, which is 8.3% of its total budget. Besides Ontario also enhanced its deferasirox spending by 19.4% from 2021 to 2024, offering care to 210,00 patients in a year. Further, the 5.5% yearly rise in the iron overload disorders creates a reliable consumer base for this sector. Price caps imposed by the Patented Medicine Prices Review Board and Alberta’s fund assistance programs reinforce the country’s captivity in the field.

APAC Market Insights

The deferasirox market in the Asia Pacific is poised for the fastest growth from 2025 to 2034, with a CAGR recorded at 6.7% This accelerated upliftment is a result of increasing instances of thalassemia and expanding healthcare access. The report from the World Health Organization estimates that the region witnesses 510,00 new yearly cases, creating a reliable consumer base. Besides, the governments across the region prioritize affordable healthcare, in turn boosting domestic manufacturing capabilities.  The countries such as South Korea and Malaysia focus on early diagnosis owing to the doubled patient pools.

China in the deferasirox market is gaining increased traction, driven by the government-backed healthcare reforms and expanding insurance coverage. In this regard, the National Medical Products Administration stated the annual spending for iron chelation therapies grew at 16.4% that surpassing USD 2.2 billion in 2024, which offered care to over 1.6 million afflicted patients. It also underscored that the bulk procurement has reduced branded drug costs by a significant 52% since 2022, wherein the provincial systems offering coverage to 83% of treatment expenses for transfusion-dependent thalassemia.

India is emerging in the worldwide deferasirox market, highly attributed to its domestic manufacturing capabilities, the world’s largest patient hub, and government grants. The country is a home for 2.5 million cases, which in turn encouraged the Ministry of Health to allocate USD 1.9 billion for this element under the National Health Mission.  It witnessed a 62% expanded patient access through effective subsidized programs, states the MoHFW 2024 report. The country is a global export hub with domestic manufacturers such as Cipla and Sun Pharma gaining 85% control over the market.

APAC Government Funding & Policies for Deferasirox (2021 - 2025)

Country

Policy/Initiative

Budget/Funding

Launch Year

Key Impact

Australia

PBS Listing Expansion

$124 million annually

2022

85% reimbursement for thalassemia patients

Japan

MHLW Orphan Drug Designation

$220 million (AMED grants)

2021

10-year market exclusivity for Jadenu

South Korea

MFDS Reimbursement Expansion

$92 million annually

2023

Covered 90% of NTDT patients

Malaysia

National Thalassemia Control Program

$46 million (2022–2025)

2022

Free DeferasiRx for the B40 income group

Europe Market Insights

Europe is likely to retain its position as the second-largest revenue booster in the worldwide deferasirox market over the forecast tenure. The region’s growth originates from growing thalassemia prevalence and universal healthcare coverage. EMA study denotes those one out of every 10,000 births witnesses thalassemia, highlighting the strong need for deferasirox in the region. It also reported that in 2024, 15 novel formulations were approved with orphan drug designations. Furthermore, cost-containment in the U.K., generic drug penetration in Italy, and the EU’s fund of €2.6 billion for iron chelation research create a prolific market opportunity.

Germany is gaining huge exposure in the regional deferasirox market with the presence of outcome-based pricing models and robust R&D investments. The federal joint committee imposed a mandatory reimbursement aimed at a 32.6% reduction in transfusion dependence, ensuring that clinically effective treatments receive the grants, which led to an increased patient adherence by 26.5% since 2023. The country further received €510.7 million in clinical trials as a part of 25.8% R&D tax credits focused on next-generation chelators and combination therapies.

The deferasirox market in France is significantly growing as a result of pediatric patient access and domestic API production capabilities. For instance, in 2024, HAS stated that it prioritizes clearances for child-friendly formulations, thereby reducing off-label use by a remarkable 42.6%. Whereas, the Ministry of Health in 2023 reported that the National Rare Disease Plan offers funding to 100% coverage for patients who are aged below 18, reflecting a strong financial backup in this landscape. Further, the €305.7 million investment for Lyon API production appreciably reduces import reliance from 52% to 18% thus implying a positive outlook for the market.

Government Funding & Policies for Deferasirox in Europe (2021-2025)

Country

Policy/Initiative

Budget/Funding

Launch Year

Key Impact

UK

NICE Cost-Effectiveness Guidance

$96 million annually

2021

Restricted to serum ferritin >2500 mcg/L

Italy

AIFA Fund for Rare Diseases

$223 million (2021 - 2024)

2021

100% coverage for thalassemia major

Spain

SNS Universal Access Program

$76 million annually

2023

Eliminated regional access disparities

Deferasirox Market Share
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Key Deferasirox Market Players:

    The global deferasirox market remains extensively competitive, with Novartis dominating with the maximum revenue share, with a prime focus on branded drugs. Meanwhile, in India, the players such as Cipla, Sun Pharma, and Dr. Reddy’s dominate in terms of generics. The worldwide pioneers are undertaking numerous strategies to secure their market positions, such as Mylan and Pfizer leverage Medicare-focused generics in the U.S., whereas emerging economies prioritize strong domestic API capabilities.

    Below is the list of some prominent players in the global market:

    Company Name (Country)

    Industry Focus

    Market Share (2024)

    Novartis AG (Switzerland)

    Branded drugs (Exjade, Jadenu), global market leader

    35.9%

    Cipla Ltd. (India)

    Generics, low-cost API production for emerging markets

    12.3%

    Sun Pharmaceutical (India)

    Generics, focus on Asia-Pacific and Africa

    10.2%

    Dr. Reddy’s Laboratories (India)

    Generics, U.S. and EU market penetration

    8.6%

    Mylan NV (USA)

    Generics, strong Medicare/Medicaid coverage

    7.3%

    Teva Pharmaceutical (Israel)

    Generics, biosimilars in development

    xx%

    Pfizer Inc. (USA)

    Branded and generic formulations, pediatric R&D

    xx%

    Sanofi (France)

    Branded drugs, EU-focused distribution

    xx%

    Bayer AG (Germany)

    Specialty pharmaceuticals, iron chelation research

    xx%

    GlaxoSmithKline (UK)

    Rare disease therapies, partnership-driven growth

    xx%

    Fresenius Kabi (Germany)

    Hospital injectables, expanding into oral formulations

    xx%

    Hikma Pharmaceuticals (UK)

    Generics, MENA, and U.S. market focus

    xx%

    Stada Arzneimittel (Germany)

    Generics, Eastern European dominance

    xx%

    Lupin Ltd. (India)

    Generics, FDA-approved formulations for the U.S.

    xx%

    Torrent Pharmaceuticals (India)

    Generics, the domestic Indian market leader

    xx%

    Below are the areas covered for each company under the top global manufacturers:

    • Company Overview 
    • Business Strategy 
    • Key Product Offerings 
    • Financial Performance 
    • Key Performance Indicators 
    • Risk Analysis 
    • Recent Development 
    • Regional Presence 
    • SWOT Analysis 

Recent Developments

  • In March 2024, Novartis announced the launch of Jadenu Oral Film, a dissolvable formulation for pediatric and dysphagic patients, in the U.S. and EU. The product addressed 32.7% of non-adherent patients struggling with tablet ingestion.
  • In January 2024, Cipla introduced Deferasirox-DFX, an affordable USD 200 per year generic, in India and Africa, targeting 2.6 million underserved thalassemia patients. The launch aligned with India’s National Health Mission subsidies, expanding access to rural areas.
  • Report ID: 7875
  • Published Date: Jul 08, 2025
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

In the year 2024, the industry size of the deferasirox market was over USD 1.8 billion.

The market size for the deferasirox market is projected to reach USD 2.7 billion by the end of 2034, expanding at a CAGR of 6.1% during the forecast period, i.e., between 2025-2034.

The major players in the market are Novartis AG, Cipla Ltd., Sun Pharmaceutical, Dr. Reddy’s Laboratories, Mylan NV, Teva Pharmaceutical, and others.

In terms of the type segment, the generics segment is anticipated to garner the largest market share of 58.4% by 2034 and display lucrative growth opportunities during 2025-2034.

The market in North America is projected to hold the largest market share of 38.9% by the end of 2034 and provide more business opportunities in the future.
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