BNP and NT-proBNP Market Size & Share, by Type (BNP Testing, NT-proBNP Testing); Technology; End user; Application; Test Setting - Global Supply & Demand Analysis, Growth Forecasts, Statistics Report 2025-2034

  • Report ID: 7866
  • Published Date: Jul 08, 2025
  • Report Format: PDF, PPT

BNP and NT-proBNP Market Outlook:

BNP and NT-proBNP Market size was over USD 2.1 billion in 2024 and is estimated to reach USD 4 billion by the end of 2034, expanding at a CAGR of 7.5% during the forecast timeline, i.e., 2025-2034. In 2025, the industry size of BNP and NT-proBNP is assessed at USD 2.2 billion.

The rising incidences of cardiovascular diseases (CVD) are the primary drivers behind the robust growth in the market. Testifying to the same, the World Health Organization (WHO) unveiled that 32.4% of deaths occurring around the globe every year are caused by CVD. Similarly, the American Heart Association revealed that the number of people afflicted with heart failure worldwide surpassed 26.3 million in 2023. This underscores the presence of a sustainable demand for these cardiac biomarkers to enable rapid and accurate diagnosis. The demographic expansion in this sector is further accelerated by the rapidly aging populations, as projections indicate 1 in 6 residents across the world to be aged over 65 by the end of 2050, as per the United Nations (UN).

Despite the growing surge, the market still faces payers' pricing pressures, with the notable rise in production costs. As evidence of this inflation, in 2024, the U.S. Bureau of Labor Statistics (BLS) recorded a 3.3% increase in the producer price index (PPI) for cardiac diagnostic reagents. This upstream flow subsequently translated to a 4.2% year-over-year (YoY) hike in the consumer price index (CPI) for diagnostic tests. This is ultimately pushing companies to adopt cost-optimized production and compliance, while maintaining access to essential cardiac biomarker testing to maintain a greater profit margins.

Bnp and Ntprobnp Market Size
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Growth Drivers ​​​​​​

  • Emergence of point-of-care testing (POCT): The shifting consumer preference toward on-site testing solutions is driving robust demand in the market. In addition, the clinical validation gained by POCTs, where the National Institute of Health (NIH) demonstrated a 40.2% faster turnaround time by using portable analyzers in U.S. hospital settings, is also establishing a strong foundation for this sector. Moreover, such efficiency gains are prompting widespread adoption. This was also evidenced by the £150.3 million investment by the National Health Service (NHS) in decentralized cardiac testing to reduce emergency room wait times.
  • Innovation in product and manufacturing: The amplifying allocations for extensive research and deployment of advanced technologies are expanding the pipeline and field of application of the BNP and NT-proBNP sector. For instance, in 2024, the NIH dedicated $480.4 million in funding for cardiovascular-related biomarker innovations. Such capital influx is further leveraging the development of next-generation assets for this sector, inspiring more institutions to invest. Additionally, manufacturers are adopting automated assembly lines for efficient production while minimizing operational, labor, and logistics expenses, according to the U.S. Census Bureau.

Historical Patient Growth (2010-2020) and Its Impact on the BNP and NT-proBNP Market Expansion

Historical Patient Growth Data (2010-2020)

Country

2010 Patients (Million)

2020 Patients (Million)

CAGR (2010-2020)

U.S.

4.3

8.2

6.9%

Germany

1.6

3.1

7.3%

France

1.3

2.5

7.2%

Spain

0.9

1.7

7.3%

Australia

0.4

0.8

9.0%

Japan

2.2

4.0

6.5%

India

0.6

2.3

16.1%

China

1.9

6.6

13.8%

Feasible Expansion Models Shaping the Future Market

Feasibility Models for Market Expansion

Model

Region

Revenue Impact (2023-2026)

Key Driver

PPP with the Govt. Hospitals

India

+12.2% CAGR

Ayushman Bharat subsidies

Automated Central Labs

U.S.

+8.1% margins

Medicare reimbursement upgrades

POCT in Rural Clinics

Kenya

+18.2% test volume

World Bank funding

AI-Driven Diagnostics

Germany

+15.4% efficiency

EU Horizon grants

Challenges

  • Regulatory delays and stringent criteria: Hurdles in acquiring compliance continue to be a persistent difficulty in the BNP and NT-proBNP market. For instance, in 2022, an 8-month delay in procuring approval from the Pharmaceuticals and Medical Devices Agency (PMDA) slowed the launch of ARCHITECT BNP by Abbott, resulting in $25.3 million in revenue loss. Similarly, the stringent regulations of the National Medical Products Administration (NMPA) extended the entry timeline of new products in China by 12-18 months. This is creating significant barriers for manufacturers seeking to expand their pipeline on a global scale.
  • Payer resistance to new technologies: Absence of adequate financial backing is increasingly becoming a significant limitation in the market by favoring only advanced technologies. For instance, in 2024, Medicare eliminated coverage for 20.4% of legacy tests while prioritizing high-sensitivity NT-proBNP assays, according to the Centers for Disease Control and Prevention (CDC). On the other hand, the HAS mandated stringent affordability criteria for POCTs, which are slowing global expansion for innovative cardiac testing solutions.

BNP and NT-proBNP Market Size and Forecast:

Report Attribute Details

Base Year

2024

Forecast Year

2025-2034

CAGR

7.5%

Base Year Market Size (2024)

USD 2.1 billion

Forecast Year Market Size (2034)

USD 4 billion

Regional Scope

  • North America (U.S., and Canada)
  • Asia Pacific (Japan, China, India, Indonesia, Malaysia, Australia, South Korea, Rest of Asia Pacific)
  • Europe (UK, Germany, France, Italy, Spain, Russia, NORDIC, Rest of Europe)
  • Latin America (Mexico, Argentina, Brazil, Rest of Latin America)
  • Middle East and Africa (Israel, GCC North Africa, South Africa, Rest of the Middle East and Africa)

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BNP and NT-proBNP Market Segmentation:

Type Segment Analysis

In terms of type, the NT-proBNP testing segment is expected to dominate the BNP and NT-proBNP market by capturing a 58.4% revenue share over the assessed period. This is primarily propelled by its superior stability and worldwide recognition. This can be exemplified by a study conducted by the NIH, which revealed that this subtype offers a 120-minute half-life in comparison to BNP's 20 minutes, reducing diagnostic errors. The segment's leadership is further reinforced by increasing reimbursement advantages, with 90.3% of U.S. laboratories preferring NT-proBNP tests due to favorable Medicare coverage policies, as per the Centers for Medicare & Medicaid Services (CMS).

Application Segment Analysis

Based on applications, the heart failure diagnosis segment is poised to represent the largest revenue share of 65.2% in the BNP and NT-proBNP market by the end of 2034. This proprietorship is backed by the enlarging burden of heart-related disorders and underlying comorbidities. This dominant position is also propelled by the reformed guidelines from the American Heart Association (AHA) that mandate BNP/NT-proBNP testing as first-line diagnostics for heart failure evaluation. Moreover, such clinical recognition and government-backed preventive initiatives are establishing this medical discipline as a critical source of revenue generation for this merchandise.

End user Segment Analysis

The hospitals & clinics segment is predicted to attain the predominant share of 47.5% in the BNP and NT-proBNP market throughout the discussed timeframe. This leadership reflects the critical role of these healthcare settings as a primary point of care for diagnosis and management in cardiac cases. Additionally, these biomarkers are incorporated in the mainstream practice in hospitals for heart failure evaluation and treatment monitoring. This dominance underscores the central position of these institutions and is empowered by continued government investment in advanced diagnostic infrastructure.

Our in-depth analysis of the global BNP and NT-proBNP market includes the following segments:

Segment

Subsegment

Type

  • BNP Testing
  • NT-proBNP Testing

Technology

  • Immunoassays
  • ELISA
  • Chemiluminescence
  • Rapid Tests

End user

  • Hospitals & Clinics
  • Diagnostic Laboratories
  • Ambulatory Care Centers

Application

  • Heart Failure Diagnosis
  • Acute Coronary Syndrome
  • Pulmonary Hypertension
  • Others

Test Setting

  • Laboratory Testing
  • Point-of-Care Testing
Vishnu Nair
Vishnu Nair
Head - Global Business Development

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BNP and NT-proBNP Market - Regional Analysis

North America Market Insights

North America is anticipated to maintain its dominance in the BNP and NT-proBNP market with a 38.4% revenue share over the analyzed timeline. The rapidly aging and obese population creates a sustainable consumer base for this sector. As evidence, more than 21.4% of the region's citizens are expected to be aged over 65 by the end of 2030. Additionally, in 2024 alone, approximately 12.2 million heart failure patients with 1.3 million new annual cases were registered in North America, according to the CDC. Furthermore, the region benefits from strong reimbursement support and technological adoption.

The U.S. is augmenting the BNP and NT-proBNP market with a regional dominance, accounting for 70.4% of demand in North America. This is backed by substantial government healthcare spending, including $1.4 billion in testing expenditure by Medicare in 2023 and $1.3 billion allocation by Medicaid, expanding coverage to 12.5 million low-income patients. Besides technological advancements, such as the FDA-cleared high-sensitivity assays and AI-integrated platforms, complement the country's strong growth in this category. Moreover, continued innovation in the U.S. is propelled by $5.2 billion allocation to CVD research by the Agency for Healthcare Research and Quality (AHRQ).

The BNP and NT-proBNP market in Canada is also growing steadily, which is supported by $3.3 billion in federal healthcare funding in 2023. In addition, the governing body of Ontario increased its spending on cardiac diagnostics by 18.3%, as per Health Canada. Furthermore, the Canadian Institute for Health Information (CIHI) reported that more than 200,003 related procedures are performed every year in public laboratories across the country. These factors cumulatively drove a 10.4% YoY rise in the high-sensitivity NT-proBNP segment.

APAC Market Insights

Asia Pacific is estimated to exhibit the highest CAGR in the global BNP and NT-proBNP market by the end of 2034. The high CVD burden, where this ailment is the origin of over 30.3% of deaths in APAC, makes the region a source of continuous surge for commodities available in this category. Additionally, the trend of healthcare modernization in emerging economies is pushing more medical settings to procure these diagnostic solutions. This landscape is led by Japan, with 70.2% hospital adoption of automated tests, as per the MHLW. Further, in South Korea, AI-powered POC devices demonstrated 25.2% cost reductions, which evolved the approach toward advanced tech-based integration in this field, according to the Ministry of Food and Drug Safety (MFDS).

China dominates the APAC BNP and NT-proBNP market with a 45.2% revenue share, which is backed by $5.9 billion government investment in cardiac biomarkers that is approved by the National Medical Products Administration (NMPA). The country's propagation in this sector also reflects strong urban hospital adoption, while unmet needs of rural regions showcase the potential to unlock $1.3 billion through expanded POCT access. Besides, the 90.2% captivity of China over the domestic API supply chain, benefiting this field with a 20.1% cost advantage, as per the Ministry of Industry and Information Technology (MIIT).

India is emerging as a hub of self-sufficiency in the regional BNP and NT-proBNP market, backed by notable improvement in rural access. In addition, 65.2% of heart failure patients in this country require these diagnoses, as reported by the Indian Council of Medical Research (ICMR). To support this cohort, the Ayushman Bharat scheme expanded rural testing availability to over 3.4 million patients every year, according to the WHO. Besides, local manufacturers, such as Transasia Bio-Medicals, are offering tests at 50.5% lower costs than multinational competitors, which supports the country's efforts to enhance the affordability of commodities in this sector.

Government Investments & Policies

Country

Policy/Initiative

Budget/Funding

(Million)

Impact

Japan

METI Healthcare 2030 (POCT Expansion)

~$120.3

(2023)

Deployed portable devices in rural clinics

South Korea

National CVD Screening Program

~$220.5

(2024)

Covered 5.3 million annual tests for high-risk populations

Australia

Rural POCT Initiative (Health Department)

~$35.1

(2025)

Targeting 50.1% access expansion in remote areas by 2027

Malaysia

BNP Test Subsidy for B40 Income Group

~$18.4

(2024)

Reduced out-of-pocket costs to $5.1 per test for low-income patients

Europe Market Insights

Europe is expected to gain the second-largest revenue share in the global BNP and NT-proBNP market during the timeline between 2025 and 2034. The aging citizens, with 20.3% of the population aged over 65 by 2030, and coordinated health initiatives are propelling adoption in this sector. The region's significance in this category is also being transformed by the expanded reimbursement for high-sensitivity assays by the insurers in France. Moreover, the €2.6 billion Health Data Space initiative is standardizing cardiac testing across 27 nations and reducing diagnostic delays by 25.1% across Europe, which empowered the merchandise, according to the European Commission (EC).

Germany dominates the Europe BNP and NT-proBNP market with a 30.1% revenue share, and this landscape is primarily driven by €4.4 billion government spending in 2024. Further, the Federal Ministry of Health in this country proved that over 90.1% hospitals adopted automated testing platforms, reflecting the nation's significance in this sector. In addition, the 2.9 million CVD patients and an aging population are attracting greater public allocations, including a 9.2% YoY increase to €420.4 million for cardiac biomarker testing in 2024. However, the AMNOG law mandates proof of "added benefit" for premium reimbursement, which is creating both challenges and opportunities in this market.

The UK is presenting lucrative opportunities for the BNP and NT-proBNP market with a remarkable transformation caused by the current trend of decentralized testing. In this regard, the NHS dedicated £300.4 million to deploying POCT devices in rural clinics, which is expanding patient access throughout the nation. Furthermore, innovative public-private collaborations are widening the scope of investments in this category. For instance, Siemens partnered with the NHS to reduce diagnostic delays by 30.1% through improved testing efficiency, reflecting the country's commitment to cultivating a modern cardiac care delivery system.

Country-wise Government Investments

Country

Policy/Initiative

Budget/Funding (Million)

Impact

France

My Health 2025 (POC Device Subsidies)

~$160.4

(2024)

Funded 5,002 rural clinic deployments

Spain

IVDR Transition Fund (AEMPS)

~$54.1

(2023)

Covered compliance costs for local manufacturers

Italy

Telemedicine Expansion for Heart Failure

~$86.2

(2025)

Linked remote BNP testing to 201+ specialist centers

Russia

Mandatory BNP Testing in Emergency Protocols

~$88.1

(2024)

Reduced heart failure misdiagnosis by 20.3%

 
Bnp and Ntprobnp Market Share
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Key BNP and NT-proBNP Market Players:

    The BNP and NT-proBNP market remains highly concentrated, with Roche, Abbott, and Siemens collectively controlling 68.1% of the global revenue share. This is gained through technological leadership in automation and AI, coupled with extensive global distribution. On the other hand, Roche dominates this sector with the launch of Medicare-backed Elecsys tests in key landscapes. Simultaneously, Abbott competes with cost-optimized systems in emerging markets. Similarly, Mindray and Transasia are also gaining traction in this aspect with affordable POC solutions.

    The cohort of such key players includes:

    Company Name

    Country

    Market Share (2024)

    Industry Focus

    Roche Diagnostics

    Switzerland

    28.3%

    Leading NT-proBNP assays (Elecsys), AI-integrated platforms

    Abbott Laboratories

    U.S.

    22.1%

    ARCHITECT BNP tests, Alinity high-throughput systems

    Siemens Healthineers

    Germany

    18.5%

    Atellica analyzers, chemiluminescence NT-proBNP assays

    bioMérieux

    France

    8.1%

    VIDAS BNP tests, POC solutions for emerging markets

    Danaher (Beckman Coulter)

    U.S.

    6.3%

    Access NT-proBNP assays, automated lab systems

    Ortho Clinical Diagnostics

    U.S.

    xx%

    VITROS BNP tests, cost-effective solutions

    Thermo Fisher Scientific

    U.S.

    xx%

    BNT ELISA kits, research-use biomarkers

    Randox Laboratories

    UK

    xx%

    Evidence POC BNP tests, rural healthcare solutions

    Mindray Medical

    China

    xx%

    CLIA-based NT-proBNP assays, expanding in Latin America

    Transasia Bio-Medicals

    India

    xx%

    ERBA BNP tests, affordable diagnostics for LMICs

    Getein Biotech

    China

    xx%

    One-step POC NT-proBNP tests, rapid diagnostics

    Snibe Diagnostics

    China

    xx%

    Maglumi NT-proBNP, automated chemiluminescence platforms

    SD Biosensor

    South Korea

    xx%

    STANDARD F NT-proBNP, AI-powered POC devices

    PerkinElmer

    U.S.

    xx%

    Research-grade BNP kits, collaboration with academic institutions

    Agappe Diagnostics

    India

    xx%

    MISPA i3 POC tests, targeting Indian public hospitals

    Boditech Med

    South Korea

    xx%

    i-CHROMA NT-proBNP, compact POC systems

    MP Biomedicals

    U.S.

    xx%

    ELISA-based BNP kits, focus on emerging markets

    Below are the areas covered for each company in the BNP and NT-proBNP market:

    • Company Overview
    • Business Strategy
    • Key Product Offerings
    • Financial Performance
    • Key Performance Indicators
    • Risk Analysis
    • Recent Development
    • Regional Presence
    • SWOT Analysis

Recent Developments

  • In May 2024, Abbott launched its Alinity HQ BNP POC device, offering a portable analyzer priced 40.1% lower than competitors. The device reduced test costs to just $10.2 per test. This expansion contributed to Abbott's 18.4% year-over-year revenue growth in the APAC region during the 3rd quarter of 2024.
  • In March 2024, Roche Diagnostics introduced its Elecsys NT-proBNP Gen 2 Assay, featuring a high-sensitivity design with 30.4% faster results (15 minutes vs. 22 minutes). The assay gained 12.2% additional market share in the U.S. and Europe by the 2nd quarter of 2024, supported by FDA clearance.
  • Report ID: 7866
  • Published Date: Jul 08, 2025
  • Report Format: PDF, PPT

Frequently Asked Questions (FAQ)

In the year 2024, the industry size of the BNP and NT-proBNP market was over USD 2.1 billion.

The market size for the BNP and NT-proBNP market is projected to reach USD 4 billion by the end of 2034, expanding at a CAGR of 7.5% during the forecast period, i.e., between 2025-2034.

The major players in the market are Roche Diagnostics, Abbott Laboratories, Siemens Healthineers, bioMérieux, Danaher (Beckman Coulter), Ortho Clinical Diagnostics, and others.

In terms of type, the nt-probnp testing segment is anticipated to garner the largest market share of 58.4% by 2034 and display lucrative growth opportunities during 2025-2034.

The market in North America is projected to hold the largest market share of 38.4% by the end of 2034 and provide more business opportunities in the future.
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